范建华 收藏
( 任职于 生物工程学院)
生物工程专业：硕士生导师 微生物学专业：硕士生导师 生物化学与分子生物学专业：硕士生导师 1984年12月生，江苏海门人，中共党员，博士，副教授，硕士生导师。 2014年入选上海市“晨光计划”，2018年入选上海市“浦江人才”计划，美国斯坦福大学卡内基科学研究所访问学者。主要研究方向：以微藻及蓝细菌等光合微生物为研究对象，围绕生物活性物质（如PUFAs，多糖，功能蛋白等）开展基础和应用基础研究，包括功能基因组学、基因表达调控、代谢途径解析与组装、基于合成生物学及生物制造推动藻类资... 详细>>
- Lipid accumulation and biosynthesis genes response of the oleaginous Chlorella pyrenoidosa under three nutrition stressors被引量：274收藏
- 作者：Fan, Jianhua Cui, Yanbin Wan, Minxi Wang, Weiliang Li, Yuanguang
- 机构：E China Univ Sci & Technol
- 来源：BIOTECHNOLOGY FOR BIOFUELS 2014
- 关键词：Nitrogen Phosphorus and iron deficiency Lipid accumulation Physiological response Gene expression Chlorella
- 质疑
- The potential and challenge of microalgae as promising future food sources被引量：139收藏
- 作者：Chen, Cheng Tang, Tao Shi, Qianwen Zhou, Zuodong Fan, Jianhua
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;East China Univ Sci & Technol;Shihezi Univ
- 来源：TRENDS IN FOOD SCIENCE & TECHNOLOGY 2022
- 关键词：Microalgae Biomass Food Safety Production
- 质疑
- Genomic Foundation of Starch-to-Lipid Switch in Oleaginous Chlorella spp.被引量：110收藏
- 作者：Fan, Jianhua Ning, Kang Zeng, Xiaowei Luo, Yuanchan Wang, Dongmei Hu, Jianqiang Li, Jing Xu, Hui Huang, Jianke Wan, Minxi Wang, Weiliang Zhang, Daojing Shen, Guomin Run, Conglin Liao, Junjie Fang, Lei Huang, Shi Jing, Xiaoyan Su, Xiaoquan Wang, Anhui Bai, Lili Hu, Zanmin Xu, Jian Li, Yuanguang
- 机构：E China Univ Sci & Technol;Chinese Acad Sci;Chinese Acad Sci;Chinese Acad Sci
- 来源：PLANT PHYSIOLOGY 2015
- 质疑
- Novel flat-plate photobioreactors for microalgae cultivation with special mixers to promote mixing along the light gradient被引量：106收藏
- 作者：Huang, Jianke Li, Yuanguang Wan, Minxi Yan, Yi Feng, Fei Qu, Xiaoxing Wang, Jun Shen, Guomin Li, Wei Fan, Jianhua Wang, Weiliang
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：Novel flat-plate photobioreactor Mixer Computational fluid dynamics Light/dark cycles Microalgae cultivation
- 质疑
- Sequential heterotrophy-dilution-photoinduction cultivation for efficient microalgal biomass and lipid production被引量：95收藏
- 作者：Fan, Jianhua Huang, Jianke Li, Yuanguang Han, Feifei Wang, Jun Li, Xinwu Wang, Weiliang Li, Shulan
- 机构：E China Univ Sci & Technol;Shanghai Zeyuan Marine Biotechnol Ltd Co
- 来源：BIORESOURCE TECHNOLOGY 2012
- 关键词：Microalgae Heterotrophy-Dilution-Photoinduction Chlorella Biomass Lipid
- 质疑
- Efficient accumulation of high-value bioactive substances by carbon to nitrogen ratio regulation in marine microalgae Porphyridium purpureum被引量：89收藏
- 作者：Li, Shaohua Ji, Liang Chen, Cheng Zhao, Shuxin Sun, Meng Gao, Zhengquan Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shandong Univ Technol
- 来源：BIORESOURCE TECHNOLOGY 2020
- 关键词：Porphyridium purpureum C/N ratio Phycoerythrin Exopolysaccharides Fatty acids
- 质疑
- The effect of temperature on cell growth and astaxanthin accumulation of Haematococcus pluvialis during a light-dark cyclic cultivation被引量：87收藏
- 作者：Wan, Minxi Zhang, Jingkui Hou, Dongmei Fan, Jianhua Li, Yuanguang Huang, Jianke Wang, Jun
- 机构：E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：Haematococcus pluvialis Astaxanthin Temperature Light-dark cyclic cultivation
- 质疑
- Sequential Heterotrophy-Dilution-Photoinduction Cultivation of Haematococcus pluvialis for efficient production of astaxanthin被引量：85收藏
- 作者：Wan, Minxi Zhang, Zhen Wang, Jun Huang, Jianke Fan, Jianhua Yu, Anquan Wang, Weiliang Li, Yuanguang
- 机构：E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Ltd Co
- 来源：BIORESOURCE TECHNOLOGY 2015
- 关键词：Haematococcus pluvialis Heterotrophy Dilution Photoinduction Astaxanthin
- 质疑
- Metabolic engineering and synthetic biology strategies for producing high-value natural pigments in Microalgae被引量：80收藏
- 作者：Cao, Kai Cui, Yulin Sun, Fengjie Zhang, Hao Fan, Jianhua Ge, Baosheng Cao, Yujiao Wang, Xiaodong Zhu, Xiangyu Wei, Zuoxi Yao, Qingshou Ma, Jinju Wang, Yu Meng, Chunxiao Gao, Zhengquan
- 机构：Binzhou Med Univ;Shandong Univ Technol;Georgia Gwinnett Coll;East China Univ Sci & Technol;China Univ Petr East China
- 来源：BIOTECHNOLOGY ADVANCES 2023
- 关键词：Microalgal pigments Synthetic pathways Metabolic modification Synthetic biology Omics technology
- 质疑
- Advances in the production of bioactive substances from marine unicellular microalgae Porphyridium spp.被引量：78收藏
- 作者：Li, Shaohua Ji, Liang Shi, Qianwen Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;Hainan Univ;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2019
- 关键词：Red algae Cultivation Metabolic regulation Application Bioactive compounds
- 质疑
- The effective photoinduction of Haematococcus pluvialis for accumulating astaxanthin with attached cultivation被引量：71收藏
- 作者：Wan, Minxi Hou, Dongmei Li, Yuanguang Fan, Jianhua Huang, Jianke Liang, Songtao Wang, Weiliang Pan, Ronghua Wang, Jun Li, Shulan
- 机构：E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd;Shanghai Zeyuan Marine Bioprod Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：Haematococcus pluvialis Astaxanthin Biomass Attached cultivation Photoinduction
- 质疑
- Bioremediation of phenolic pollutants by algae-current status and challenges被引量：60收藏
- 作者：Wu, Ping Zhang, Zhaofei Luo, Yeling Bai, Yunpeng Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2022
- 关键词：Algae Phenolic pollutants Removal mechanisms Industrial value
- 质疑
- Evaluation of Microalgae as Immunostimulants and Recombinant Vaccines for Diseases Prevention and Control in Aquaculture被引量：58收藏
- 作者：Ma, Ke Bao, Qiuwen Wu, Yue Chen, Siwei Zhao, Shuxin Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 2020
- 关键词：aquaculture industry microalgae immunostimulant oral vaccine polymicrobial infections
- 质疑
- Phycobiliproteins from algae: Current updates in sustainable production and applications in food and health被引量：58收藏
- 作者：Ji, Liang Qiu, Sheng Wang, Zhiheng Zhao, Chenni Tang, Bo Gao, Zhengquan Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shihezi Univ;Nantong Focusee Biotechnol Co Ltd;Binzhou Med Univ
- 来源：FOOD RESEARCH INTERNATIONAL 2023
- 关键词：Phycoerythrin Phycocyanin Allophycocyanin Algae Food Biomedicine
- 质疑
- Enhancement of microalgal biomass and lipid productivities by a model of photoautotrophic culture with heterotrophic cells as seed被引量：54收藏
- 作者：Han, Feifei Huang, Jianke Li, Yuanguang Wang, Weiliang Wang, Jun Fan, Jianhua Shen, Guomin
- 机构：E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Ltd Co
- 来源：BIORESOURCE TECHNOLOGY 2012
- 关键词：Biofuels Chlorella spp Heterotrophic seed Biomass and lipid productivities Neutral lipid
- 质疑
- Transcriptome-based global analysis of gene expression in response to carbon dioxide deprivation in the green algae Chlorella pyrenoidosa被引量：50收藏
- 作者：Fan, Jianhua Xu, Hui Li, Yuanguang
- 机构：E China Univ Sci & Technol
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2016
- 关键词：Chlorella CO2 Growth Carbon concentrating mechanism Gene expression
- 质疑
- Dietary supplementation with microalgae enhances the zebrafish growth performance by modulating immune status and gut microbiota被引量：50收藏
- 作者：Ma, Ke Chen, Siwei Wu, Yue Ma, Yiting Qiao, Haochen Fan, Jianhua Wu, Haizhen
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2022
- 关键词：Microalgae Zebrafish Growth performance Immune status Gut microbiota
- 质疑
- Comparative transcriptome analyses of oleaginous Botryococcus braunii race A reveal significant differences in gene expression upon cobalt enrichment 06 Biological Sciences 0601 Biochemistry and Cell Biology被引量：48收藏
- 作者：Cheng, Pengfei Zhou, Chengxu Wang, Yan Xu, Zhihui Xu, Jilin Zhou, Dongqing Zhang, Yinghui Wu, Haizhen Zhang, Xuezhi Liu, Tianzhong Tang, Ming Yang, Qiyong Yan, Xiaojun Fan, Jianhua
- 机构： College of Food and Pharmaceutical Sciences; State Key Laboratory of Bioreactor Engineering; Department of Applied Biology; Institute of Hydrobiology; Key Laboratory of Biofuels
- 来源：Biotechnology for Biofuels 2018
- 关键词：Physiology - Biochemistry - Hydrocarbons - Metabolism - Photosynthesis - Fatty acids - Gene expression - Carbon - Biosynthesis - Cytology - Physiological models
- 质疑
- 微藻能源技术开发和产业化的发展思路与策略被引量：44收藏
- 作者：黄英明 王伟良 李元广 谢静莉 范建华 陶黎明
- 机构：中国生物技术发展中心;华东理工大学生物反应器工程国家重点实验室
- 来源：《生物工程学报》 2010
- 关键词：微藻能源 技术开发 产业化 发展策略
- 摘要：随着石油资源的日益减少及实现低碳经济的迫切需要,微藻能源已成为世界各国重点研究与发展的战略方向。微藻能源关系国家能源重大战略储备,因此我国迫切需要自主开发微藻能源产业化技术。文中分析了我国发展微藻能源的优势,及目前微藻能...
- 下载全文在线阅读质疑
- Trihexyltetradecylphosphonium Chloride Based Ratiometric Fluorescent Nano-Optodes for Multiplex Anion Discrimination被引量：42收藏
- 作者：Liu, Yueling Fan, Jianhua Xu, Huiying Zhang, Ni Su, Wei Zhou, Jinfeng Qin, Yu Jiang, Dechen
- 机构： State Key Laboratory of Bioreactor Engineering; State Key Laboratory of Analytical Chemistry for Life science; Department of Applied Biology
- 来源：SSRN 2022
- 关键词：Beverages - Chlorine compounds - Colorimetry - Fluorescence - Medical applications - Negative ions - Nitrates
- 质疑
- Efficient heterotrophic cultivation of Chlamydomonas reinhardtii被引量：41收藏
- 作者：Zhang, Zhen Tan, Yingying Wang, Weiliang Bai, Wenmin Fan, Jianhua Huang, Jianke Wan, Minxi Li, Yuanguang
- 机构：East China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd
- 来源：JOURNAL OF APPLIED PHYCOLOGY 2019
- 关键词：Chlamydomonas reinhardtii Chlorophyceae Heterotrophy Scale-up Cultivation
- 质疑
- Acclimation to NaCl and light stress of heterotrophic Chlamydomonas reinhardtii for lipid accumulation被引量：40收藏
- 作者：Fan, Jianhua Zheng, Lvhong
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOSCIENCE AND BIOENGINEERING 2017
- 关键词：Chlamydomonas reinhardtii Salt and light stress Heterotrophy Lipid Physiological acclimation
- 质疑
- Impacts of CO2 concentration on growth, lipid accumulation, and carbon-concentrating-mechanism-related gene expression in oleaginous Chlorella被引量：38收藏
- 作者：Fan, Jianhua Xu, Hui Luo, Yuanchan Wan, Minxi Huang, Jianke Wang, Weiliang Li, Yuanguang
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2015
- 关键词：Chlorella CO2 Growth Lipid Carbon-concentrating mechanism Gene expression
- 质疑
- Stable nuclear transformation of the industrial alga Chlorella pyrenoidosa被引量：36收藏
- 作者：Run, Conglin Fang, Lei Fan, Jianhua Fan, Chengming Luo, Yuanchan Hu, Zanmin Li, Yuanguang
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2016
- 关键词：Genetic engineering Electroporation Chlorella pyrenoidosa Nuclear transformation eGFP
- 质疑
- Flocculation of Chlamydomonas reinhardtii with Different Phenotypic Traits by Metal Cations and High pH被引量：31收藏
- 作者：Fan, Jianhua Zheng, Lvhong Bai, Yunpeng Saroussi, Shai Grossman, Arthur R.
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Carnegie Inst Sci
- 来源：FRONTIERS IN PLANT SCIENCE 2017
- 关键词：flocculation cell wall deficient Chlamydomonas multivalent metal ions microalgae pH algal biotechnology
- 质疑
- Transgenic eukaryotic microalgae as green factories: providing new ideas for the production of biologically active substances被引量：27收藏
- 作者：Shi, Qianwen Chen, Cheng Zhang, Wei Wu, Ping Sun, Meng Wu, Hui Wu, Haizhen Fu, Pengcheng Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Hainan Univ
- 来源：JOURNAL OF APPLIED PHYCOLOGY 2021
- 关键词：Eukaryotic microalgae Genetic engineering Metabolism Biopharmaceuticals production Therapeutic proteins
- 质疑
- Physiological and transcriptome analysis elucidates the metabolic mechanism of versatile Porphyridium purpureum under nitrogen deprivation for exopolysaccharides accumulation被引量：26收藏
- 作者：Ji, Liang Li, Shaohua Chen, Cheng Jin, Haojie Wu, Haizhen Fan, Jianhua
- 机构：East China Univ Sci & Technol;Beijing Forestry Univ;East China Univ Sci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2021
- 关键词：Porphyridium purpureum Nitrogen deprivation Transcriptome analysis Exopolysaccharides Polyunsaturated fatty acids Phycoerythrin
- 质疑
- Repeated mutagenic effects of 60Co-γ irradiation coupled with high-throughput screening improves lipid accumulation in mutant strains of the microalgae Chlorella pyrenoidosa as a feedstock for bioenergy被引量：26收藏
- 作者：Wang, Weiliang Wei, Tingting Fan, Jianhua Yi, Jun Li, Yuanguang Wan, Minxi Wang, Jun Bai, Wenmin
- 机构：East China Univ Sci & Technol;JiaxingZeyuan Bioprod Ltd Co
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2018
- 关键词：Chlorella pyrenoidosa Co-60-gamma irradiation mutagenesis Lipid Bioenergy
- 质疑
- The effect of nutrition pattern alteration on Chlorella pyrenoidosa growth, lipid biosynthesis-related gene transcription被引量：24收藏
- 作者：Fan, Jianhua Cui, Yanbin Zhou, Yang Wan, Minxi Wang, Weiliang Xie, Jingli Li, Yuanguang
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：Chlorella Lipid Gene expression Heterotrophy Photoautotrophy
- 质疑
- Efficient degradation of sulfadiazine by photosynthetic cyanobacteria Synechocystis sp. PCC 6803 coupling with recombinant laccase strategy被引量：23收藏
- 作者：Wu, Ping Hu, Tianyouzi Sun, Liyun Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shihezi Univ;130 Meilong Rd
- 来源：CHEMICAL ENGINEERING JOURNAL 2023
- 关键词：Synechocystis Sulfadiazine Bioremediation Laccase Microalgae
- 质疑
