万民熙 收藏
( 任职于 生物工程学院)
1981年9月生，湖南衡阳人，中美联合培养博士，生物工程专业硕士生导师。入选2015年度华东理工大学青年英才引进与培育计划。 近十年来，一直从事微生物选育、生理生化和分子生物学相关基础研究。针对微藻代谢产物的合成与基因遗传改造进行了大量研究工作，涉及生理生化、细胞生物学、分子生物学、代谢调控以及功能基因组学等方面的相关工作。通过全转录组测序、细胞代谢过程的碳流向解析、环境刺激与细胞互作机制研究等多种手段找到了能源微藻基因工程改造的关键基因。目前正在从事雨生红球藻高产虾青素的工艺开发和基因工程改造等研究工作。作为项目负责人承担国家高技术研究发展计划（863）课题、国家自然科学基金、中国博... 详细>>
- Lipid accumulation and biosynthesis genes response of the oleaginous Chlorella pyrenoidosa under three nutrition stressors被引量：274收藏
- 作者：Fan, Jianhua Cui, Yanbin Wan, Minxi Wang, Weiliang Li, Yuanguang
- 机构：E China Univ Sci & Technol
- 来源：BIOTECHNOLOGY FOR BIOFUELS 2014
- 关键词：Nitrogen Phosphorus and iron deficiency Lipid accumulation Physiological response Gene expression Chlorella
- 质疑
- Genomic Foundation of Starch-to-Lipid Switch in Oleaginous Chlorella spp.被引量：110收藏
- 作者：Fan, Jianhua Ning, Kang Zeng, Xiaowei Luo, Yuanchan Wang, Dongmei Hu, Jianqiang Li, Jing Xu, Hui Huang, Jianke Wan, Minxi Wang, Weiliang Zhang, Daojing Shen, Guomin Run, Conglin Liao, Junjie Fang, Lei Huang, Shi Jing, Xiaoyan Su, Xiaoquan Wang, Anhui Bai, Lili Hu, Zanmin Xu, Jian Li, Yuanguang
- 机构：E China Univ Sci & Technol;Chinese Acad Sci;Chinese Acad Sci;Chinese Acad Sci
- 来源：PLANT PHYSIOLOGY 2015
- 质疑
- Novel flat-plate photobioreactors for microalgae cultivation with special mixers to promote mixing along the light gradient被引量：106收藏
- 作者：Huang, Jianke Li, Yuanguang Wan, Minxi Yan, Yi Feng, Fei Qu, Xiaoxing Wang, Jun Shen, Guomin Li, Wei Fan, Jianhua Wang, Weiliang
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：Novel flat-plate photobioreactor Mixer Computational fluid dynamics Light/dark cycles Microalgae cultivation
- 质疑
- The effect of temperature on cell growth and astaxanthin accumulation of Haematococcus pluvialis during a light-dark cyclic cultivation被引量：87收藏
- 作者：Wan, Minxi Zhang, Jingkui Hou, Dongmei Fan, Jianhua Li, Yuanguang Huang, Jianke Wang, Jun
- 机构：E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：Haematococcus pluvialis Astaxanthin Temperature Light-dark cyclic cultivation
- 质疑
- Sequential Heterotrophy-Dilution-Photoinduction Cultivation of Haematococcus pluvialis for efficient production of astaxanthin被引量：85收藏
- 作者：Wan, Minxi Zhang, Zhen Wang, Jun Huang, Jianke Fan, Jianhua Yu, Anquan Wang, Weiliang Li, Yuanguang
- 机构：E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Ltd Co
- 来源：BIORESOURCE TECHNOLOGY 2015
- 关键词：Haematococcus pluvialis Heterotrophy Dilution Photoinduction Astaxanthin
- 质疑
- Improving performance of flat-plate photobioreactors by installation of novel internal mixers optimized with computational fluid dynamics被引量：82收藏
- 作者：Huang, Jianke Feng, Fei Wan, Minxi Ying, Jiangguo Li, Yuanguang Qu, Xiaoxing Pan, Ronghua Shen, Guomin Li, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;JiaxingZeyuan Bioprod Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2015
- 关键词：Flat-plate photobioreactors Mixer Computational fluid dynamics Light/dark cycles Photosynthetic efficiency
- 质疑
- Enhanced lipid productivity of Chlorella pyrenoidosa through the culture strategy of semi-continuous cultivation with nitrogen limitation and pH control by CO2被引量：80收藏
- 作者：Han, Feifei Huang, Jianke Li, Yuanguang Wang, Weiliang Wan, Minxi Shen, Guomin Wang, Jun
- 机构：E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Ltd Co
- 来源：BIORESOURCE TECHNOLOGY 2013
- 关键词：Chlorella pH control Nitrogen limitation Semi-continuous culture Lipid productivity
- 质疑
- The effective photoinduction of Haematococcus pluvialis for accumulating astaxanthin with attached cultivation被引量：71收藏
- 作者：Wan, Minxi Hou, Dongmei Li, Yuanguang Fan, Jianhua Huang, Jianke Liang, Songtao Wang, Weiliang Pan, Ronghua Wang, Jun Li, Shulan
- 机构：E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd;Shanghai Zeyuan Marine Bioprod Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：Haematococcus pluvialis Astaxanthin Biomass Attached cultivation Photoinduction
- 质疑
- The effect of iron on growth, lipid accumulation, and gene expression profile of the freshwater microalga Chlorella sorokiniana被引量：70收藏
- 作者：Wan, Minxi Jin, Xuejie Xia, Jinlan Rosenberg, Julian N. Yu, Geng Nie, Zhenyuan Oyler, George A. Betenbaugh, Michael J.
- 机构：E China Univ Sci & Technol;Cent S Univ;Johns Hopkins Univ;Univ Nebraska
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2014
- 关键词：Chlorella sorokiniana Fe Lipid biosynthesis qPCR Genefishing
- 质疑
- Changes of biomass, lipid content and fatty acids composition under a light-dark cyclic culture of Chlorella pyrenoidosa in response to different temperature被引量：54收藏
- 作者：Han, Feifei Wang, Weiliang Li, Yuanguang Shen, Guomin Wan, Minxi Wang, Jun
- 机构：E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Ltd Co
- 来源：BIORESOURCE TECHNOLOGY 2013
- 关键词：Lipid content Fatty acids composition Temperature Microalgae
- 质疑
- Dynamic modelling of Haematococcus pluvialis photoinduction for astaxanthin production in both attached and suspended photobioreactors被引量：51收藏
- 作者：Zhang, Dongda Wan, Minxi del Rio-Chanona, Ehecatl A. Huang, Jianke Wang, Weiliang Li, Yuanguang Vassiliadis, Vassilios S.
- 机构：Univ Cambridge;E China Univ Sci & Technol
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2016
- 关键词：Astaxanthin Dynamic simulation Light attenuation Temperature Suspended photobioreactor Attached photobioreactor
- 质疑
- Investigation on the performance of raceway ponds with internal structures by the means of CFD simulations and experiments被引量：48收藏
- 作者：Huang, Jianke Qu, Xiaoxing Wan, Minxi Ying, Jiangguo Li, Yuanguang Zhu, Faochao Wang, Jun Shen, Guomin Chen, Jianpei Li, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2015
- 关键词：Raceway pond Computational fluid dynamics Particle Image Velocimetry Mixing Microalgae cultivation
- 质疑
- A novel paradigm for the high-efficient production of phycocyanin from Galdieria sulphuraria被引量：45收藏
- 作者：Wan, Minxi Wang, Zhenyang Zhang, Zhen Wang, Jun Li, Shulan Yu, Anquan Li, Yuanguang
- 机构：East China Univ Sci & Technol;Yunnan Shangrila Zeyuan Ltd Co Algal Hlth Technol;Jiaxing Zeyuan Bioprod Co Ltd
- 来源：BIORESOURCE TECHNOLOGY 2016
- 关键词：Sequential Heterotrophy-Dilution-Photoinduction Galdieria sulphuraria Phycocyanin
- 质疑
- Comparison of C-phycocyanin from extremophilic Galdieria sulphuraria and Spirulina platensis on stability and antioxidant capacity被引量：43收藏
- 作者：Wan, Minxi Zhao, Haoyu Guo, Jiacai Yan, Lulu Zhang, Daojing Bai, Wenmin Li, Yuanguang
- 机构：East China Univ Sci & Technol;Baoshan Zeyuan Algae Hlth Technol Co Ltd
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2021
- 关键词：Phycocyanin Thermostability Galdieria sulphuraria
- 质疑
- Efficient heterotrophic cultivation of Chlamydomonas reinhardtii被引量：41收藏
- 作者：Zhang, Zhen Tan, Yingying Wang, Weiliang Bai, Wenmin Fan, Jianhua Huang, Jianke Wan, Minxi Li, Yuanguang
- 机构：East China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd
- 来源：JOURNAL OF APPLIED PHYCOLOGY 2019
- 关键词：Chlamydomonas reinhardtii Chlorophyceae Heterotrophy Scale-up Cultivation
- 质疑
- Impacts of CO2 concentration on growth, lipid accumulation, and carbon-concentrating-mechanism-related gene expression in oleaginous Chlorella被引量：38收藏
- 作者：Fan, Jianhua Xu, Hui Luo, Yuanchan Wan, Minxi Huang, Jianke Wang, Weiliang Li, Yuanguang
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2015
- 关键词：Chlorella CO2 Growth Lipid Carbon-concentrating mechanism Gene expression
- 质疑
- Numerical and experimental study on the performance of flat-plate photobioreactors with different inner structures for microalgae cultivation被引量：34收藏
- 作者：Huang, Jianke Kang, Shaofeng Wan, Minxi Li, Yuanguang Qu, Xiaoxing Feng, Fei Wang, Jun Wang, Weiliang Shen, Guomin Li, Wei
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd
- 来源：JOURNAL OF APPLIED PHYCOLOGY 2015
- 关键词：Flat-plate photobioreactor Computational fluid dynamics Mixing Light regime characteristics Microalgae cultivation
- 质疑
- Repeated mutagenic effects of 60Co-γ irradiation coupled with high-throughput screening improves lipid accumulation in mutant strains of the microalgae Chlorella pyrenoidosa as a feedstock for bioenergy被引量：26收藏
- 作者：Wang, Weiliang Wei, Tingting Fan, Jianhua Yi, Jun Li, Yuanguang Wan, Minxi Wang, Jun Bai, Wenmin
- 机构：East China Univ Sci & Technol;JiaxingZeyuan Bioprod Ltd Co
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2018
- 关键词：Chlorella pyrenoidosa Co-60-gamma irradiation mutagenesis Lipid Bioenergy
- 质疑
- The effect of nutrition pattern alteration on Chlorella pyrenoidosa growth, lipid biosynthesis-related gene transcription被引量：24收藏
- 作者：Fan, Jianhua Cui, Yanbin Zhou, Yang Wan, Minxi Wang, Weiliang Xie, Jingli Li, Yuanguang
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：Chlorella Lipid Gene expression Heterotrophy Photoautotrophy
- 质疑
- Investigation on models for light distribution of Haematococcus pluvialis during astaxanthin accumulation stage with an application case被引量：21收藏
- 作者：Sheng, Bin Fan, Fei Huang, Jianke Bai, Wenmin Wang, Jun Li, Sulan Li, Wei Wan, Minxi Li, Yuanguang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shangri La Zeyuan Algae Hlth Technol Co Ltd;Baoshan Zeyuan Algae Hlth Technol Co Ltd;Shanghai Zeyuan Marine Biotechnol Co Ltd
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2018
- 关键词：Light attenuation model Haematococcus pluvialis CFD Induction experiment
- 质疑
- Evaluating the effects of geometry and arrangement parameter of flat panel photobioreactor on microalgae biomass production and economic performance in China被引量：21收藏
- 作者：Huang, Jianke Wan, Minxi Jiang, Jingshun Zhang, Aihua Zhang, Daofeng
- 机构：Hohai Univ;East China Univ Sci & Technol
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2021
- 关键词：Microalgae Biomass productivity Techno-economic analysis Flat panel PBR Design scenarios
- 质疑
- Modeling of astaxanthin production in the two-stage cultivation of Haematococcus pluvialis and its application on the optimization of vertical multi-column airlift photobioreactor被引量：20收藏
- 作者：Fan, Fei Wan, Minxi Huang, Jianke Wang, Weiliang Bai, Wenmin He, Maolei Li, Yuanguang
- 机构：East China Univ Sci & Technol;Hohai Univ;Baoshan Zeyuan Algae Hlth Technol Co Ltd
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2021
- 关键词：H pluvialis Astaxanthin production Modeling Vertical multi-column airlift photobioreactor
- 质疑
- High-yield cultivation of Botryococcus braunii for biomass and hydrocarbons被引量：18收藏
- 作者：Wan, Minxi Zhang, Zhen Wang, Ruixuan Bai, Wenmin Huang, Jianke Wang, Weiliang Shen, Guomin Yu, Anquan Li, Yuanguang
- 机构：East China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd;Yunnan Baoshan Zeyuan Microalgae Hlth Technol Co
- 来源：BIOMASS & BIOENERGY 2019
- 关键词：Botryococcus braunii Hydrocarbon Heterotrophy Photoautotrophy
- 质疑
- A new PMA-qPCR method for rapid and accurate detection of viable bacteria and spores of marine-derived Bacillus velezensis B-9987被引量：18收藏
- 作者：Guo, Jiacai Wang, Weiliang Zhao, Haoyu Luo, Yuanchan Wan, Minxi Li, Yuanguang
- 机构：East China Univ Sci & Technol;Mail Box 301
- 来源：JOURNAL OF MICROBIOLOGICAL METHODS 2022
- 关键词：BacillusvelezensisB-9987 Propidiummonoazide qPCR SporegenomicDNA Viablebacterianumber
- 质疑
- Astaxanthin accumulation difference between non-motile cells and akinetes of Haematococcus pluvialis was affected by pyruvate metabolism被引量：16收藏
- 作者：Fang, Lei Zhang, Jingkui Fei, Zhongnan Wan, Minxi
- 机构：East China Univ Sci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2020
- 关键词：Astaxanthin Haematococcus pluvialis Pyruvate Transcriptome
- 质疑
- Chlorophyll as key indicator to evaluate astaxanthin accumulation ability of Haematococcus pluvialis被引量：15收藏
- 作者：Fang, Lei Zhang, Jingkui Fei, Zhongnan Wan, Minxi
- 机构：East China Univ Sci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2019
- 关键词：Astaxanthin Chlorophyll Haematococcus pluvialis Metabolic network Transcriptome analysis
- 质疑
- Comparative transcriptome analysis of astaxanthin accumulation difference between non-motile cells and akinetes of Haematococcus pluvialis被引量：15收藏
- 作者：Fang, Lei Zhang, Jingkui Fei, Zhongnan Wan, Minxi
- 机构： State Key Laboratory of Bioreactor Engineering; Mail box 301
- 来源：Research Square 2020
- 关键词：Biochemistry - Biosynthesis - Carboxylation - Cytology - Genes - Metabolism
- 质疑
- Improving astaxanthin production of Haematococcus pluvialis on the outdoor large scale cultivation by optimizing the disinfection strategy of photobioreactor被引量：15收藏
- 作者：Fei, Zhongnan Fan, Fei Liao, Junjie Wan, Minxi Bai, Wenmin Wang, Weiliang He, Maolei Li, Yuanguang
- 机构：East China Univ Sci & Technol;Baoshan Zeyuan Algae Hlth Technol Co Ltd
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2022
- 关键词：Sodium hypochlorite Haematococcus pluvialis Biological contaminants Degradation model Astaxanthin production
- 质疑
- Design and optimization of a novel airlift-driven sloping raceway pond with numerical and practical experiments被引量：14收藏
- 作者：Huang, Jianke Yang, Qijian Chen, Jianpei Wan, Minxi Ying, Jiangguo Fan, Fei Wang, Jun Li, Wei Li, Yuanguang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Jiaxing Zeyuan Bioprod Co Ltd
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2016
- 关键词：Airlift-driven sloping raceway pond Computational fluid dynamics Mixing Microalgae cultivation
- 质疑
- A novel method for extraction of paramylon from Euglena gracilis for industrial production被引量：12收藏
- 作者：Zhang, Kaikai Wan, Minxi Bai, Wenmin He, Maolei Wang, Weiliang Fan, Fei Guo, Jiacai Yu, Tao Li, Yuanguang
- 机构：East China Univ Sci & Technol;Baoshan Zeyuan Algae Hlth Technol Co Ltd;Mai Box 301
- 来源：ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 2023
- 关键词：Paramylon Disc stack centrifuge E gracilis concentrate SDS Response surface methodology Pilot-scale extraction
- 质疑
