魏东芝 收藏
( 任职于 生物工程学院鲁华生物技术研究所)
魏东芝：教授，博士生导师，鲁华生物技术研究所所长。 鲁华所的创始人和领导者。 国家重点学科—生物化工学科带头人。上海市重点学科-生物工程学科带头人。 中国能源学会副理事长，中国酶工程专业委员会副主任委员, 中国生物工程学会理事，工业和环境生物技术专业委员会委员,国家教育指导委员会委员，中科院“百人计划”入选者，上海科技发展重点领域技术预见专家，上海生物工程学会常务理事，上海生物化学与分子生物学学会常务理事，上海生物医药行业协会理事，中－韩生物技术指导委员会委... 详细>>
被引量：16,556H指数：51SCI-EXPANDED： 587 EI： 425 北大核心： 182 CSCD： 219
- Antioxidant activity of a flavonoid-rich extract of Hypericum perforatum L. in vitro被引量：546收藏
- 作者：Zou, YP Lu, YH Wei, DZ
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2004
- 关键词：Hypericum perforatum L. antioxidant activity flavonoid free radicals reducing power lipid peroxidation liposome deoxyribose degradation
- 质疑
- Relationship between the structure, physicochemical properties and in vitro digestibility of rice starches with different amylose contents被引量：434收藏
- 作者：Chung, Hyun-Jung Liu, Qiang Lee, Laurence Wei, Dongzhi
- 机构：Agr & Agri Food Canada;Heilongjiang Beidahuang Potato Ind Co Ltd;E China Univ Sci & Technol
- 来源：FOOD HYDROCOLLOIDS 2011
- 关键词：Rice starch Amylose content Amylopectin chain length distribution Crystalline structure In vitro digestibility
- 质疑
- The yeast peroxisome: A dynamic storage depot and subcellular factory for squalene overproduction被引量：194收藏
- 作者：Liu, Guo-Song Li, Tian Zhou, Wei Jiang, Min Tao, Xin-Yi Liu, Min Zhao, Ming Ren, Yu-Hong Gao, Bei Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2020
- 关键词：Synthetic biology Saccharomyces cerevisiae Peroxisome Storage depot Subcellular factory Terpene
- 质疑
- Phytochemical Profiles of Different Mulberry (Morus sp.) Species from China被引量：142收藏
- 作者：Song, Wei Wang, Han-Jing Bucheli, Peter Zhang, Pei-Fang Wei, Dong-Zhi Lu, Yan-Hua
- 机构：E China Univ Sci & Technol;Nestle R&D Ctr Beijing Ltd
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2009
- 关键词：Mulberry (Morus sp.) DNJ (1-deoxynojirimycin) resveratrol oxyresveratrol anthocyanin flavonoid
- 质疑
- Microbial production of 2,3-butanediol by a mutagenized strain of Serratia marcescens H30被引量：125收藏
- 作者：Zhang, Liaoyuan Yang, Yunlong Sun, Jian'an Shen, Yaling Wei, Dongzhi Zhu, Jiawen Chu, Ju
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2010
- 关键词：2,3-Butanediol Serratia marcescens H30 Respiratory quotient Medium optimization Fed-batch
- 质疑
- Metabolic compartmentalization in yeast mitochondria: Burden and solution for squalene overproduction被引量：115收藏
- 作者：Zhu, Zhan-Tao Du, Meng-Meng Gao, Bei Tao, Xin-Yi Zhao, Ming Ren, Yu-Hong Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2021
- 关键词：Saccharomyces cerevisiae Mitochondrial engineering Metabolic burden Squalene Dual engineering
- 质疑
- Characterization and engineering of 3-ketosteroid-Δ1-dehydrogenase and 3-ketosteroid-9α-hydroxylase in Mycobacterium neoaurum ATCC 25795 to produce 9α-hydroxy-4-androstene-3,17-dione through the catabolism of sterols被引量：99收藏
- 作者：Yao, Kang Xu, Li-Qin Wang, Feng-Qing Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2014
- 关键词：3-Ketosteroid-Delta(1)-dehydrogenase Mycobacteria Sterols 9 alpha-Hydroxy-4-androstene-3,17-dione
- 质疑
- Enhanced acetoin production by Serratia marcescens H32 with expression of a water-forming NADH oxidase被引量：96收藏
- 作者：Sun, Jian-An Zhang, Liao-Yuan Rao, Ben Shen, Ya-Ling Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol;Fujian Agr & Forestry Univ
- 来源：BIORESOURCE TECHNOLOGY 2012
- 关键词：Acetoin 2,3-Butanediol Serratia marcescens Cofactor engineering Fermentation
- 质疑
- Identification and engineering of cholesterol oxidases involved in the initial step of sterols catabolism in Mycobacterium neoaurum被引量：93收藏
- 作者：Yao, Kang Wang, Feng-Qing Zhang, Huai-Cheng Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2013
- 关键词：Cholesterol oxidase Mycobacteria Sterols Androst-4-ene-3,17-dione Androst-1,4-diene-3,17-dione
- 质疑
- Lipase-catalyzed irreversible transesterification of vegetable oils for fatty acid methyl esters production with dimethyl carbonate as the acyl acceptor被引量：89收藏
- 作者：Su, Er-Zheng Zhang, Min-Jie Zhang, Jian-Guo Gao, Jian-Feng Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol;Shihezi Univ
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2007
- 关键词：dimethyl carbonate (DMC) acyl acceptor fatty acid methyl esters (FAMES) novozym435 transesterification cottonseed oil
- 质疑
- Microbial production of 2,3-butanediol by a surfactant (serrawettin)-deficient mutant of Serratia marcescens H30被引量：87收藏
- 作者：Zhang, Liaoyuan Sun, Jian'an Hao, Yingli Zhu, Jiawen Chu, Ju Wei, Dongzhi Shen, Yaling
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2010
- 关键词：2,3-Butanediol Serrawettin W1 synthase Inactivation Serratia marcescens Fed-batch
- 质疑
- Antihypertensive Effects, Molecular Docking Study, and Isothermal Titration Calorimetry Assay of Angiotensin I-Converting Enzyme Inhibitory Peptides from Chlorella vulgaris被引量：87收藏
- 作者：Xie, Jingli Chen, Xujun Wu, Junjie Zhang, Yanyan Zhou, Yan Zhang, Lujia Tang, Ya-Jie Wei, Dongzhi
- 机构：East China Univ Sci & Technol;Hubei Univ Technol;Shanghai Business Sch;SCICB
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2018
- 关键词：Chlorella vulgaris ACE inhibitory peptides anti hypertensive activity molecular docking isothermal titration calorimetry
- 质疑
- Purification of L(+)-lactic acid from fermentation broth with paper sludge as a cellulosic feedstock using weak anion exchanger Amberlite IRA-92被引量：84收藏
- 作者：Tong, Wang-Yu Fu, Xiang-Yang Lee, Sang-Mok Yu, Jie Liu, Jian-Wen Wei, Dong-Zhi Koo, Yoon-Mo
- 机构：E China Univ Sci & Technol;Inha Univ;Zhejiang Univ
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2004
- 关键词：fermentation ion exchange lactic acid optimization paper sludge purification
- 质疑
- In vitro and in vivo ACE inhibitory of pistachio hydrolysates and in silico mechanism of identified peptide binding with ACE被引量：77收藏
- 作者：Li, Peng Jia, Jia Fang, Ming Zhang, Lujia Guo, Mingrong Xie, Jingli Xia, Yuelan Zhou, Li Wei, Dongzhi
- 机构：E China Univ Sci & Technol;Shandong Silk Text Vocat Coll
- 来源：PROCESS BIOCHEMISTRY 2014
- 关键词：ACE inhibitory peptide Molecular docking Pistacia vera L. Purification Spontaneously hypertensive rats (SHRs)
- 质疑
- Metabolic Engineering of Saccharomyces cerevisiae To Overproduce Squalene被引量：71收藏
- 作者：Li, Tian Liu, Guo-Song Zhou, Wei Jiang, Min Ren, Yu-Hong Tao, Xin-Yi Liu, Min Zhao, Ming Wang, Feng-Qing Gao, Bei Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2020
- 关键词：Saccharomyces cerevisiae metabolic engineering squalene overproduction ethanol carbon source utilization
- 质疑
- In situ lipase-catalyzed reactive extraction of oilseeds with short-chained dialkyl carbonates for biodiesel production被引量：69收藏
- 作者：Su, Erzheng You, Pengyong Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2009
- 关键词：In situ Reactive extraction Short-chained dialkyl carbonates Biodiesel
- 质疑
- In vitro and in vivo antioxidant activities of a flavonoid isolated from celery (Apium graveolens L. var. dulce)被引量：66收藏
- 作者：Li, Peng Jia, Jia Zhang, Daihui Xie, Jingli Xu, Xueshu Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：FOOD & FUNCTION 2014
- 关键词：Assays - Brain - Plants (botany) - Free radicals - Column chromatography - Antioxidants
- 质疑
- A novel psychrophilic lipase from Pseudomonas fluorescens with unique property in chiral resolution and biodiesel production via transesterification被引量：66收藏
- 作者：Luo, Yu Zheng, Yitao Jiang, Zhengbing Ma, Yushu Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2006
- 质疑
- Inactivation and Augmentation of the Primary 3-Ketosteroid-Δ1-Dehydrogenase in Mycobacterium neoaurum NwIB-01: Biotransformation of Soybean Phytosterols to 4-Androstene-3,17-Dione or 1,4-Androstadiene-3,17-Dione被引量：63收藏
- 作者：Wei, Wei Wang, Feng-qing Fan, Shu-yue Wei, Dong-zhi
- 机构：E China Univ Sci & Technol
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2010
- 质疑
- Enhanced production of dihydroxyacetone from glycerol by overexpression of glycerol dehydrogenase in an alcohol dehydrogenase-deficient mutant of Gluconobacter oxydans被引量：62收藏
- 作者：Li, Ming-hua Wu, Jian Liu, Xu Lin, Jin-ping Wei, Dong-zhi Chen, Hao
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2010
- 关键词：Gluconobacter oxydans Glycerol dehydrogenase Dihydroxyacetone Biotransformation Glycerol
- 质疑
- Hypocholesterolemic effects of a flavonoid-rich extract of Hypericum perforatum L. in rats fed a cholesterol-rich diet被引量：62收藏
- 作者：Zou, YP Lu, YH Wei, DZ
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2005
- 关键词：Hypericum perforatum L. flavonoids hypocholesterolemic serum lipid levels malondialdehyde antioxidant enzymes
- 质疑
- 谷胱甘肽的简便测定法被引量：57收藏
- 作者：赵旭东 魏东芝 万群 俞俊棠
- 机构：华东理工大学生物反应器工程国家重点实验室
- 来源：《药物分析杂志》 2000
- 关键词：谷胱甘肽 甲醛 关胱氨酸 DTNB
- 摘要：目的： 建立一种快速简便测定谷胱甘肽的新方法。方法： 样品１ 式２ 份， ｐＨ８－０ 条件下分别和甲醛反应２ｍｉｎ 和６０ ｍｉｎ， 各取１ ｍＬ加入５ ｍＬＤＴＮＢ溶液， ２５ ℃反应５ ｍｉｎ 后分别测定在波长４１２...
- 下载全文在线阅读质疑
- A novel esterase from a marine mud metagenomic library for biocatalytic synthesis of short-chain flavor esters被引量：55收藏
- 作者：Gao, Wenyuan Wu, Kai Chen, Lifeng Fan, Haiyang Zhao, Zhiqiang Gao, Bei Wang, Hualei Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：MICROBIAL CELL FACTORIES 2016
- 关键词：Metagenomic library Functional screening Esterase Transesterification Short-chain flavor esters High substrate loading
- 质疑
- Significantly Enhanced Production of Patchoulol in Metabolically Engineered Saccharomyces cerevisiae被引量：53收藏
- 作者：Ma, Bin Liu, Min Li, Zhen-Hai Tao, Xinyi Wei, Dong-Zhi Wang, Feng-Qing
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：patchoulol sesquiterpene metabolic engineering Saccharomyces cerevisiae terpenoids
- 质疑
- Reversion of multidrug resistance by tumor targeted delivery of antisense oligodeoxynucleotides in hydroxypropyl-chitosan nanoparticles被引量：52收藏
- 作者：Wang, Jiaqi Tao, Xinyi Zhang, Yufei Wei, Dongzhi Ren, Yuhong
- 机构：E China Univ Sci & Technol
- 来源：BIOMATERIALS 2010
- 关键词：Hydroxypropyl-chitosan nanoparticles Tumor-targeted Antisense oligodeoxynucleotides Multidrug resistance
- 质疑
- Metabolic engineering of Pichia pastoris for the production of dammarenediol-II被引量：51收藏
- 作者：Liu, Xin-Bin Liu, Min Tao, Xin-Yi Zhang, Zhong-Xi Wang, Feng-Qing Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2015
- 关键词：Dammarenediol-II Metabolic engineering Pichia pastoris Ginsenosides 2,3-Oxidosqualene
- 质疑
- Engineering of Trichoderma reesei for enhanced degradation of lignocellulosic biomass by truncation of the cellulase activator ACE3被引量：50收藏
- 作者：Chen, Yumeng Wu, Chuan Fan, Xingjia Zhao, Xinqing Zhao, Xihua Shen, Tao Wei, Dongzhi Wang, Wei
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Jiangxi Normal Univ;Sunson Ind Grp Co Ltd
- 来源：BIOTECHNOLOGY FOR BIOFUELS 2020
- 关键词：Trichoderma reesei Genetic engineering Truncated ACE3 Cellulase production Lignocellulosic biomass
- 质疑
- Cofermentation of Bacillus licheniformis and Gluconobacter oxydans for chitin extraction from shrimp waste被引量：50收藏
- 作者：Liu, Pei Liu, Shanshan Guo, Na Mao, Xiangzhao Lin, Hong Xue, Changhu Wei, Dongzhi
- 机构：Ocean Univ China;E China Univ Sci & Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2014
- 关键词：Bacillus licheniformis Gluconobacter oxydans Waste treatment Fermentation Biodegradation Proteolysis
- 质疑
- Asymmetric oxidation by Gluconobacter oxydans被引量：48收藏
- 作者：Gao, KL Wei, DZ
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2006
- 质疑
- High cell density fermentation of Gluconobacter oxydans DSM 2003 for glycolic acid production被引量：48收藏
- 作者：Wei, Guodong Yang, Xuepeng Gan, Tula Zhou, Wenyu Lin, Jinping Wei, Dongzhi
- 机构：E China Univ Sci & Technol;Zhengzhou Univ Light Ind
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2009
- 关键词：Gluconobacter oxydans Uniform design Fed-batch High-density fermentation Bioconversion Ethylene glycol Glycolic acid
- 质疑
