魏东芝 收藏
( 任职于 生物工程学院鲁华生物技术研究所)
魏东芝：教授，博士生导师，鲁华生物技术研究所所长。 鲁华所的创始人和领导者。 国家重点学科—生物化工学科带头人。上海市重点学科-生物工程学科带头人。 中国能源学会副理事长，中国酶工程专业委员会副主任委员, 中国生物工程学会理事，工业和环境生物技术专业委员会委员,国家教育指导委员会委员，中科院“百人计划”入选者，上海科技发展重点领域技术预见专家，上海生物工程学会常务理事，上海生物化学与分子生物学学会常务理事，上海生物医药行业协会理事，中－韩生物技术指导委员会委... 详细>>
被引量：16,556H指数：51SCI-EXPANDED： 587 EI： 425 北大核心： 182 CSCD： 219
- Antioxidant activity of a flavonoid-rich extract of Hypericum perforatum L. in vitro被引量：546收藏
- 作者：Zou, YP Lu, YH Wei, DZ
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2004
- 关键词：Hypericum perforatum L. antioxidant activity flavonoid free radicals reducing power lipid peroxidation liposome deoxyribose degradation
- 质疑
- Relationship between the structure, physicochemical properties and in vitro digestibility of rice starches with different amylose contents被引量：434收藏
- 作者：Chung, Hyun-Jung Liu, Qiang Lee, Laurence Wei, Dongzhi
- 机构：Agr & Agri Food Canada;Heilongjiang Beidahuang Potato Ind Co Ltd;E China Univ Sci & Technol
- 来源：FOOD HYDROCOLLOIDS 2011
- 关键词：Rice starch Amylose content Amylopectin chain length distribution Crystalline structure In vitro digestibility
- 质疑
- The yeast peroxisome: A dynamic storage depot and subcellular factory for squalene overproduction被引量：194收藏
- 作者：Liu, Guo-Song Li, Tian Zhou, Wei Jiang, Min Tao, Xin-Yi Liu, Min Zhao, Ming Ren, Yu-Hong Gao, Bei Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2020
- 关键词：Synthetic biology Saccharomyces cerevisiae Peroxisome Storage depot Subcellular factory Terpene
- 质疑
- An improved 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) reduction assay for evaluating the viability of Escherichia coli cells被引量：181收藏
- 作者：Wang, Hengwei Cheng, Hairong Wang, Fengqing Wei, Dongzhi Wang, Xuedong
- 机构：E China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：JOURNAL OF MICROBIOLOGICAL METHODS 2010
- 关键词：MTT reduction Formazan E. coli Viability
- 质疑
- Phytochemical Profiles of Different Mulberry (Morus sp.) Species from China被引量：142收藏
- 作者：Song, Wei Wang, Han-Jing Bucheli, Peter Zhang, Pei-Fang Wei, Dong-Zhi Lu, Yan-Hua
- 机构：E China Univ Sci & Technol;Nestle R&D Ctr Beijing Ltd
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2009
- 关键词：Mulberry (Morus sp.) DNJ (1-deoxynojirimycin) resveratrol oxyresveratrol anthocyanin flavonoid
- 质疑
- Microbial production of 2,3-butanediol by a mutagenized strain of Serratia marcescens H30被引量：125收藏
- 作者：Zhang, Liaoyuan Yang, Yunlong Sun, Jian'an Shen, Yaling Wei, Dongzhi Zhu, Jiawen Chu, Ju
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2010
- 关键词：2,3-Butanediol Serratia marcescens H30 Respiratory quotient Medium optimization Fed-batch
- 质疑
- Metabolic compartmentalization in yeast mitochondria: Burden and solution for squalene overproduction被引量：115收藏
- 作者：Zhu, Zhan-Tao Du, Meng-Meng Gao, Bei Tao, Xin-Yi Zhao, Ming Ren, Yu-Hong Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2021
- 关键词：Saccharomyces cerevisiae Mitochondrial engineering Metabolic burden Squalene Dual engineering
- 质疑
- Characterization and engineering of 3-ketosteroid-Δ1-dehydrogenase and 3-ketosteroid-9α-hydroxylase in Mycobacterium neoaurum ATCC 25795 to produce 9α-hydroxy-4-androstene-3,17-dione through the catabolism of sterols被引量：99收藏
- 作者：Yao, Kang Xu, Li-Qin Wang, Feng-Qing Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2014
- 关键词：3-Ketosteroid-Delta(1)-dehydrogenase Mycobacteria Sterols 9 alpha-Hydroxy-4-androstene-3,17-dione
- 质疑
- Protective effects of hyperoside (quercetin-3-o-galactoside) to PC12 cells against cytotoxicity induced by hydrogen peroxide and tert-butyl hydroperoxide被引量：99收藏
- 作者：Liu, ZY Tao, XY Zhang, CW Lu, YH Wei, DZ
- 机构：E China Univ Sci & Technol
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2005
- 关键词：hyperoside hydrogen peroxide tert-butyl hydroperoxide PC12 cells
- 质疑
- Enhanced acetoin production by Serratia marcescens H32 with expression of a water-forming NADH oxidase被引量：96收藏
- 作者：Sun, Jian-An Zhang, Liao-Yuan Rao, Ben Shen, Ya-Ling Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol;Fujian Agr & Forestry Univ
- 来源：BIORESOURCE TECHNOLOGY 2012
- 关键词：Acetoin 2,3-Butanediol Serratia marcescens Cofactor engineering Fermentation
- 质疑
- Identification and engineering of cholesterol oxidases involved in the initial step of sterols catabolism in Mycobacterium neoaurum被引量：93收藏
- 作者：Yao, Kang Wang, Feng-Qing Zhang, Huai-Cheng Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2013
- 关键词：Cholesterol oxidase Mycobacteria Sterols Androst-4-ene-3,17-dione Androst-1,4-diene-3,17-dione
- 质疑
- Antimetastatic effect of prodigiosin through inhibition of tumor invasion被引量：90收藏
- 作者：Zhang, J Shen, YL Liu, JW Wei, DZ
- 机构：E China Univ Sci & Technol
- 来源：BIOCHEMICAL PHARMACOLOGY 2005
- 关键词：prodigiosin metastasis invasion MMPs RhoA
- 质疑
- Lipase-catalyzed irreversible transesterification of vegetable oils for fatty acid methyl esters production with dimethyl carbonate as the acyl acceptor被引量：89收藏
- 作者：Su, Er-Zheng Zhang, Min-Jie Zhang, Jian-Guo Gao, Jian-Feng Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol;Shihezi Univ
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2007
- 关键词：dimethyl carbonate (DMC) acyl acceptor fatty acid methyl esters (FAMES) novozym435 transesterification cottonseed oil
- 质疑
- Microbial production of 2,3-butanediol by a surfactant (serrawettin)-deficient mutant of Serratia marcescens H30被引量：87收藏
- 作者：Zhang, Liaoyuan Sun, Jian'an Hao, Yingli Zhu, Jiawen Chu, Ju Wei, Dongzhi Shen, Yaling
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2010
- 关键词：2,3-Butanediol Serrawettin W1 synthase Inactivation Serratia marcescens Fed-batch
- 质疑
- Antihypertensive Effects, Molecular Docking Study, and Isothermal Titration Calorimetry Assay of Angiotensin I-Converting Enzyme Inhibitory Peptides from Chlorella vulgaris被引量：87收藏
- 作者：Xie, Jingli Chen, Xujun Wu, Junjie Zhang, Yanyan Zhou, Yan Zhang, Lujia Tang, Ya-Jie Wei, Dongzhi
- 机构：East China Univ Sci & Technol;Hubei Univ Technol;Shanghai Business Sch;SCICB
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2018
- 关键词：Chlorella vulgaris ACE inhibitory peptides anti hypertensive activity molecular docking isothermal titration calorimetry
- 质疑
- Purification of L(+)-lactic acid from fermentation broth with paper sludge as a cellulosic feedstock using weak anion exchanger Amberlite IRA-92被引量：84收藏
- 作者：Tong, Wang-Yu Fu, Xiang-Yang Lee, Sang-Mok Yu, Jie Liu, Jian-Wen Wei, Dong-Zhi Koo, Yoon-Mo
- 机构：E China Univ Sci & Technol;Inha Univ;Zhejiang Univ
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2004
- 关键词：fermentation ion exchange lactic acid optimization paper sludge purification
- 质疑
- Modulation of P-glycoprotein function and reversal of multidrug resistance by (-)-epigallocatechin gallate in human cancer cells被引量：82收藏
- 作者：Qian, F Wei, DZ Zhang, Q Yang, SL
- 机构：E China Univ Chem Technol
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2005
- 关键词：(-)-epigallocatechin gallate multidrug resistance P-glycoprotein
- 质疑
- Fe3+-induced oxidation and coordination cross-linking in catechol-chitosan hydrogels under acidic pH conditions被引量：82收藏
- 作者：Guo, Zhongwei Ni, Kefeng Wei, Dongzhi Ren, Yuhong
- 机构：E China Univ Sci & Technol
- 来源：RSC ADVANCES 2015
- 关键词：pH - Self assembly - Phenols - Chitosan - Hydrogels - Gelation
- 质疑
- Unraveling and engineering the production of 23,24-bisnorcholenic steroids in sterol metabolism被引量：80收藏
- 作者：Xu, Li-Qin Liu, Yong-Jun Yao, Kang Liu, Hao-Hao Tao, Xin-Yi Wang, Feng-Qing Wei, Dong-Zhi
- 机构：E China Univ Sci & Technol
- 来源：SCIENTIFIC REPORTS 2016
- 质疑
- The Important Role of Halogen Bond in Substrate Selectivity of Enzymatic Catalysis被引量：78收藏
- 作者：Jiang, Shuiqin Zhang, Lujia Cui, Dongbin Yao, Zhiqiang Gao, Bei Lin, Jinping Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：SCIENTIFIC REPORTS 2016
- 质疑
- In vitro and in vivo ACE inhibitory of pistachio hydrolysates and in silico mechanism of identified peptide binding with ACE被引量：77收藏
- 作者：Li, Peng Jia, Jia Fang, Ming Zhang, Lujia Guo, Mingrong Xie, Jingli Xia, Yuelan Zhou, Li Wei, Dongzhi
- 机构：E China Univ Sci & Technol;Shandong Silk Text Vocat Coll
- 来源：PROCESS BIOCHEMISTRY 2014
- 关键词：ACE inhibitory peptide Molecular docking Pistacia vera L. Purification Spontaneously hypertensive rats (SHRs)
- 质疑
- Chemical fingerprint and quantitative analysis of Salvia plebeia R.Br. by high-performance liquid chromatography被引量：74收藏
- 作者：Jin, Xiao-feng Lu, Yan-hua Wei, Dong-zhi Wang, Zheng-tao
- 机构：E China Univ Sci & Technol;Shanghai Univ TCM
- 来源：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 2008
- 关键词：Salvia plebeia R.Br. HPLC quality control fingerprint
- 质疑
- Mutant library construction in directed molecular evolution: Casting a wider net被引量：74收藏
- 作者：Wang, Tian-Wen Zhu, Hu Ma, Xing-Yuan Zhang, Ting Ma, Yu-Shu Wei, Dong-Zhi
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Molecular Biotechnology 2006
- 关键词：Cells - DNA - Enzymes - Molecular biology - Mutagenesis - Mutagens
- 质疑
- The transcription factor ACE3 controls cellulase activities and lactose metabolism via two additional regulators in the fungus Trichoderma reesei被引量：71收藏
- 作者：Zhang, Jiajia Chen, Yumeng Wu, Chuan Liu, Pei Wang, Wei Wei, Dongzhi
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOLOGICAL CHEMISTRY 2019
- 关键词：Trichoderma reesei transcription factor protein-protein interaction cellulase DNA binding protein protein-DNA interaction gene expression fungi Hypocrea jecorina gene knockout ace3 protein-protein interaction transcription factor Trichoderma reesei (Hypocrea jecorina) Zn(II)2Cys6 protein renewables gene regulation hydrolase transcriptomics
- 质疑
- Metabolic Engineering of Saccharomyces cerevisiae To Overproduce Squalene被引量：71收藏
- 作者：Li, Tian Liu, Guo-Song Zhou, Wei Jiang, Min Ren, Yu-Hong Tao, Xin-Yi Liu, Min Zhao, Ming Wang, Feng-Qing Gao, Bei Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2020
- 关键词：Saccharomyces cerevisiae metabolic engineering squalene overproduction ethanol carbon source utilization
- 质疑
- In situ lipase-catalyzed reactive extraction of oilseeds with short-chained dialkyl carbonates for biodiesel production被引量：69收藏
- 作者：Su, Erzheng You, Pengyong Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2009
- 关键词：In situ Reactive extraction Short-chained dialkyl carbonates Biodiesel
- 质疑
- Artificial Multienzyme Supramolecular Device: Highly Ordered Self-Assembly of Oligomeric Enzymes In Vitro and In Vivo被引量：68收藏
- 作者：Gao, Xin Yang, Shuai Zhao, Chengcheng Ren, Yuhong Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2014
- 关键词：biocatalysis enzyme catalysis oligomerization self-assembly supramolecular chemistry
- 质疑
- A novel psychrophilic lipase from Pseudomonas fluorescens with unique property in chiral resolution and biodiesel production via transesterification被引量：66收藏
- 作者：Luo, Yu Zheng, Yitao Jiang, Zhengbing Ma, Yushu Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2006
- 质疑
- In vitro and in vivo antioxidant activities of a flavonoid isolated from celery (Apium graveolens L. var. dulce)被引量：66收藏
- 作者：Li, Peng Jia, Jia Zhang, Daihui Xie, Jingli Xu, Xueshu Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：FOOD & FUNCTION 2014
- 关键词：Assays - Brain - Plants (botany) - Free radicals - Column chromatography - Antioxidants
- 质疑
