成果/Result
- Reproductive Effects of Two Neonicotinoid Insecticides on Mouse Sperm Function and Early Embryonic Development In Vitro被引量：88收藏
- 作者：Gu, Yi-hua Li, Yan Huang, Xue-feng Zheng, Ju-fen Yang, Jun Diao, Hua Yuan, Yao Xu, Yan Liu, Miao Shi, Hui-juan Xu, Wen-ping
- 机构：Fudan Univ;Fudan Univ;Wenzhou Med Univ;E China Univ Sci & Technol
- 来源：PLOS ONE 2013
- Ivermectin induces cell cycle arrest and apoptosis of HeLa cells via mitochondrial pathway被引量：72收藏
- 作者：Zhang, Ping Zhang, Yang Liu, Kuikui Liu, Bin Xu, Wenping Gao, Jufang Ding, Lei Tao, Liming
- 机构：East China Univ Sci & Technol;Shandong Acad Pharmaceut Sci;Vegetable Tech Extens Stn Qingpu Dist Shanghai;Shanghai Normal Univ
- 来源：CELL PROLIFERATION 2019
- 关键词：antimigratory effects apoptosis cell cycle arrest cervical cancer ivermectin mitochondrial pathway
- Effects of Glyphosate on Zebrafish (Danio rerio) Developmental Toxicity被引量：63收藏
- 作者：Zhou, Ning Li, Ruirui Lu, Jin Cheng, Jiagao Xu, Wenping Tao, Liming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Frog Prince Baby & Child Care Product Co. Ltd.
- 来源：Environmental Toxicology 2025
- 关键词：Aquatic organisms - Herbicides - Weed control
- Characterization of hepatotoxic effects induced by pyraclostrobin in human HepG2 cells and zebrafish larvae被引量：60收藏
- 作者：Wu, Mengqi Bian, Jinhao Han, Shuang Zhang, Cheng Xu, Wenping Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology; State Key Laboratory of Bioreactor Engineering
- 来源：Chemosphere 2023
- 关键词：Activation analysis - Disease control - Mitochondria
- Developmental toxicity and estrogenicity of glyphosate in zebrafish in vivo and in silico studies被引量：58收藏
- 作者：Lu, Jian Zhang, Cheng Xu, Wenping Chen, Weidong Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：Chemosphere 2023
- 关键词：Animals - Deep learning - Endocrine disrupters - Herbicides
- Avermectin Confers Its Cytotoxic Effects by Inducing DNA Damage and Mitochondria-Associated Apoptosis被引量：56收藏
- 作者：Zhang, Yang Luo, Mingming Xu, Wenping Yang, Mingjun Wang, Bo Gao, Jufang Li, Yaxiao Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ;Univ Bath
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2016
- 关键词：avermectin cytotoxic effects DNA damage apoptosis mitochondrial pathway
- In Vivo Visualization of γ-Glutamyl Transpeptidase Activity with an Activatable Self-Immobilizing Near-Infrared Probe被引量：56收藏
- 作者：Li, Yuyao Xue, Chenghong Fang, Zhijun Xu, Weipan Xie, Hexin
- 机构：East China Univ Sci & Technol
- 来源：ANALYTICAL CHEMISTRY 2020
- 关键词：Mammals - Quinone - Enzyme activity - Probes - Cytology - Infrared devices
- Characterization of glyphosate-induced cardiovascular toxicity and apoptosis in zebrafish被引量：55收藏
- 作者：Lu, Jian Wang, Weiguo Zhang, Cheng Xu, Wenping Chen, Weidong Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构：East China Univ Sci & Technol;UT southwestern Med Ctr
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词：Glyphosate Developmental toxicity Heart Vascular Apoptosis Zebra fish
- Cytotoxic effects of Avermectin on human HepG2 cells in vitro bioassays被引量：51收藏
- 作者：Zhang, Yang Wu, Jigang Xu, Wenping Gao, Jufang Cao, Haijing Yang, Mingjun Wang, Bo Hao, Youwu Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2017
- 关键词：Environmental toxicity Pesticide Avermectin HepG2 cells Cytotoxic effects Mitochondrial-mediated apoptosis
- Spinosad induces programmed cell death involves mitochondrial dysfunction and cytochrome C release in Spodoptera frugiperda Sf9 cells被引量：51收藏
- 作者：Yang, Mingjun Wang, Bo Gao, Jufang Zhang, Yang Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：CHEMOSPHERE 2017
- 关键词：Spinosad Programmed cell death Mitochondrial dysfunction Cytochrome C release
- Characterization of Glyphosate-Induced Cardiovascular Toxicity and Apoptosis in Zebrafish Embryos被引量：49收藏
- 作者：Lu, Jian Wang, Weiguo Zhang, Cheng Xu, Wenping Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：SSRN 2022
- 关键词：Cell death - Health hazards - Herbicides
- Natural pyrethrins induces apoptosis in human hepatocyte cells via Bax- and Bcl-2-mediated mitochondrial pathway被引量：48收藏
- 作者：Yang, Yun Zong, Mimi Xu, Wenping Zhang, Yang Wang, Bo Yang, Mingjun Tao, Liming
- 机构：East China Univ Sci & Technol
- 来源：CHEMICO-BIOLOGICAL INTERACTIONS 2017
- 关键词：Natural pyrethrins Cytotoxic effects Human hepatocyte cells Apoptosis The mitochondrial pathway
- Induction of developmental toxicity and cardiotoxicity in zebrafish embryos by Emamectin benzoate through oxidative stress被引量：46收藏
- 作者：Lu, Jian Wang, Weiguo Xu, Wenping Zhang, Chenggong Zhang, Cheng Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;Shanghai Municipal Bur Publ Secur;UT Southwestern Med Ctr
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词：Emamectin benzoate Developmental toxicity Oxidative stress Cardiotoxicity Zebrafish
- Cardiotoxicity risk induced by sanitary insecticide Dimefluthrin被引量：45收藏
- 作者：Li, Ruirui Zhou, Ning Zhang, Cheng Wu, Mengqi Xu, Wenping Cheng, Jiagao Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：Chemosphere 2024
- 关键词：Cell death - Health risks - Heart - Insecticides - Polymerase chain reaction - Risk management
- Difenoconazole induces oxidative DNA damage and mitochondria mediated apoptosis in SH-SY5Y cells被引量：42收藏
- 作者：Wang, Xin Ni, Hongfei Xu, Wenping Wu, Bing Xie, Te Zhang, Cheng Cheng, Jiagao Li, Zhong Tao, Liming Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：CHEMOSPHERE 2021
- 关键词：Difenoconazole Cytotoxicity DNA damage Apoptosis Human neuroblastoma SH-SY5Y cells
- Effects of Glyphosate on Zebrafish(Danio Rerio)Neural Development被引量：41收藏
- 作者：Zhou, Ning Li, Ruirui Wu, Mengqi Xu, Wenping Tao, Liming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology
- 来源：SSRN 2024
- 关键词：Animals - Gene expression - Herbicides - Pathology
- A Study on the Sex Pheromone Dispenser Application for Spodoptera Frugiperda Management on Maize被引量：39收藏
- 作者：Xu, Zhiping Wang, Xinqian Liu, Bin Zhang, Yang Xu, Wenping
- 机构： Shanghai Key Lab of Chemical Biology
- 来源：SSRN 2023
- 关键词：Bacteriology - Pest control - Water treatment
- Dimefluthrin induces female-specific reproductive toxicity in zebrafish (Danio rerio) after long-term exposure to low concentrations被引量：39收藏
- 作者：Wang, Wei-Guo Li, Rui-Rui Yang, Ming-Jun Hu, Jing-Ying Xu, Wen-Ping Tao, Li-Ming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; State Key Laboratory of Bioreactor Engineering; NHC Key Lab of Reproduction Regulation
- 来源：SSRN 2026
- 关键词：Endocrine disrupters - Endocrinology - Insecticides - Physiology - Public health - Toxicity
- Natural pyrethrins induce autophagy of HepG2 cells through the activation of AMPK/mTOR pathway被引量：38收藏
- 作者：Yang, Yun Gao, Jufang Zhang, Yang Xu, Wenping Hao, Youwu Xu, Zhiping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2018
- 关键词：Natural pyrethrins Autophagy HepG2 cells Oxidative stress AMPK/mTOR pathway
- Evaluation of the cytotoxic effects of glyphosate herbicides in human liver, lung, and nerve被引量：37收藏
- 作者：Hao, Youwu Zhang, Yang Ni, Hongfei Gao, Jufang Yang, Yun Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 2019
- 关键词：Cytotoxicity ethoxylated formulant glyphosate herbicide human health pesticide
- The effects of Spinosad on zebrafish larvae and THP-1 cells: Associated with immune cell damage and NF-kappa B signaling pathway activation被引量：37收藏
- 作者：Wang, Wei-Guo Xiong, Shou-Qian Lu, Jin Zhu, Lian-Hua Zhang, Cheng Cheng, Jia-Gao Li, Zhong Xu, Wen-Ping Tao, Li-Ming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology; Frog Prince Baby&Child Care Product Co.
- 来源：Chemosphere 2023
- 关键词：Antigen-antibody reactions - Cell signaling - Cytology - Macrophages - Signaling
- Induction of Developmental Toxicity and Cardiotoxicity in Zebrafish Embryos by Emamectin Be Nzoatethrough Oxidative Stress被引量：37收藏
- 作者：Lu, Jian Xu, Wenping Wang, Weiguo Zhang, Chenggong Zhang, Cheng Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Institute of forensic science shanghai municipal public security bureau; Department of Pathology
- 来源：SSRN 2021
- 关键词：Blood - Cell death - Toxicity - Transcription
- Roundup? confers cytotoxicity through DNA damage and Mitochondria-Associated apoptosis induction被引量：32收藏
- 作者：Hao, Youwu Chen, Hui Xu, Wenping Gao, Jufang Yang, Yun Zhang, Yang Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2019
- 关键词：Glyphosate-based herbicide Cytotoxicity DNA damage Mitochondria-associated apoptosis Human health risk
- The Association between Exposure to Environmental Bisphenol A and Gonadotropic Hormone Levels among Men被引量：26收藏
- 作者：Liang, Hong Xu, Wenping Chen, Jianping Shi, Huijuan Zhu, Jiang Liu, Xiaoqin Wang, Jian Miao, Maohua Yuan, Wei
- 机构：Fudan Univ;East China Univ Sci & Technol;Fudan Univ;Populat & Family Planning Inst Guizhou Prov;Aarhus Univ
- 来源：PLOS ONE 2017
- Exposure to environmental concentrations of natural pyrethrins induces hepatotoxicity: Assessment in HepG2 cell lines and zebrafish models被引量：25收藏
- 作者：Lu, Jian Yang, Yun Zhu, Lianhua Li, Meng Xu, Wenping Zhang, Cheng Cheng, Jiagao Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：CHEMOSPHERE 2022
- 关键词：Natural pyrethrins Hepatotoxicity Oxidative stress DNA damage Repair HepG2 cells Zebrafish
- Pyrethrum-extract induced autophagy in insect cells: A new target?被引量：21收藏
- 作者：Xu, Zhiping Lu, Miaoqing Yang, Mingjun Xu, Wenping Gao, Jufang Zhang, Yang Yang, Yun Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 2017
- 关键词：Insecticide Pyrethrum-extract Sf9 cells Cytotoxicity Autophagy
- Staurosporine shows insecticidal activity against Mythimna separata Walker (Lepidoptera: Noctuidae) potentially via induction of apoptosis被引量：21收藏
- 作者：Zhang, Yang Liu, Songlin Yang, Xing Yang, Mingjun Xu, Wenping Li, Yaxiao Tao, Liming
- 机构：E China Univ Sci & Technol;Shanghai Pesticide Res Inst;Univ Bath
- 来源：PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 2016
- 关键词：Insecticidal activity Staurosporine Mythimna separata Walker Apoptosis Sf9 cells The mitochondrial pathway
- Spinosad induces autophagy of Spodoptera frugiperda Sf9 cells and the activation of AMPK/mTOR signaling pathway被引量：21收藏
- 作者：Yang, Mingjun Hao, Youwu Gao, Jufang Zhang, Yang Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY 2017
- 关键词：Spinosad Sf9 cells Autophagy AMPK mTOR
- The insecticide spinosad induces DNA damage and apoptosis in HEK293 and HepG2 cells被引量：21收藏
- 作者：Yang, Mingjun Xiang, Guanggang Li, Diqiu Zhang, Yang Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol
- 来源：MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 2016
- 关键词：Spinosad DNA damage Comet assay H2AX foci Apoptosis Cytotoxic
- Spinetoram confers its cytotoxic effects by inducing AMPK/mTOR-mediated autophagy and oxidative DNA damage被引量：21收藏
- 作者：Zhang, Yang Guo, Wei Chen, Hui Gao, Jufang Xu, Zhiping Tao, Liming Li, Zhong Xu, Wenping
- 机构：East China Univ Sci & Technol;China Crop Protect Ind Assoc;Shanghai Normal Univ
- 来源：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2019
- 关键词：Spinetoram Cytotoxic effects Mitochondrial dysfunction AMPK/mTOR-mediated autophagy Oxidative DNA damage
