成果/Result
- Ivermectin induces cell cycle arrest and apoptosis of HeLa cells via mitochondrial pathway被引量：72收藏
- 作者：Zhang, Ping Zhang, Yang Liu, Kuikui Liu, Bin Xu, Wenping Gao, Jufang Ding, Lei Tao, Liming
- 机构：East China Univ Sci & Technol;Shandong Acad Pharmaceut Sci;Vegetable Tech Extens Stn Qingpu Dist Shanghai;Shanghai Normal Univ
- 来源：CELL PROLIFERATION 2019
- 关键词：antimigratory effects apoptosis cell cycle arrest cervical cancer ivermectin mitochondrial pathway
- Effects of Glyphosate on Zebrafish (Danio rerio) Developmental Toxicity被引量：63收藏
- 作者：Zhou, Ning Li, Ruirui Lu, Jin Cheng, Jiagao Xu, Wenping Tao, Liming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Frog Prince Baby & Child Care Product Co. Ltd.
- 来源：Environmental Toxicology 2025
- 关键词：Aquatic organisms - Herbicides - Weed control
- Characterization of hepatotoxic effects induced by pyraclostrobin in human HepG2 cells and zebrafish larvae被引量：60收藏
- 作者：Wu, Mengqi Bian, Jinhao Han, Shuang Zhang, Cheng Xu, Wenping Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology; State Key Laboratory of Bioreactor Engineering
- 来源：Chemosphere 2023
- 关键词：Activation analysis - Disease control - Mitochondria
- Developmental toxicity and estrogenicity of glyphosate in zebrafish in vivo and in silico studies被引量：58收藏
- 作者：Lu, Jian Zhang, Cheng Xu, Wenping Chen, Weidong Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：Chemosphere 2023
- 关键词：Animals - Deep learning - Endocrine disrupters - Herbicides
- Surface Morphology and the Action Mechanism of Macrophage Immuno-Stimulating Activity of Rosa Setate X Rosa Rugosa Polysaccharide Wsrp-1b被引量：57收藏
- 作者：Wu, Mengqi Xu, Jingying Li, Wei Han, Qifeng Xia, Wei Li, Zhong Zhang, Yang Zhang, Wenqing
- 机构： Shanghai Key Laboratory of Chemical Biology; Shanghai Key Laboratory of Functional Materials Chemistry; State Key Laboratory of Dairy Biotechnology
- 来源：SSRN 2023
- 关键词：Antigen-antibody reactions - Azo dyes - Disease control - Electrophoresis - Morphology - Nitric oxide - Scanning electron microscopy - Surface morphology
- Avermectin Confers Its Cytotoxic Effects by Inducing DNA Damage and Mitochondria-Associated Apoptosis被引量：56收藏
- 作者：Zhang, Yang Luo, Mingming Xu, Wenping Yang, Mingjun Wang, Bo Gao, Jufang Li, Yaxiao Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ;Univ Bath
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2016
- 关键词：avermectin cytotoxic effects DNA damage apoptosis mitochondrial pathway
- Characterization of glyphosate-induced cardiovascular toxicity and apoptosis in zebrafish被引量：55收藏
- 作者：Lu, Jian Wang, Weiguo Zhang, Cheng Xu, Wenping Chen, Weidong Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构：East China Univ Sci & Technol;UT southwestern Med Ctr
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词：Glyphosate Developmental toxicity Heart Vascular Apoptosis Zebra fish
- Spinosad induces programmed cell death involves mitochondrial dysfunction and cytochrome C release in Spodoptera frugiperda Sf9 cells被引量：51收藏
- 作者：Yang, Mingjun Wang, Bo Gao, Jufang Zhang, Yang Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：CHEMOSPHERE 2017
- 关键词：Spinosad Programmed cell death Mitochondrial dysfunction Cytochrome C release
- Cytotoxic effects of Avermectin on human HepG2 cells in vitro bioassays被引量：51收藏
- 作者：Zhang, Yang Wu, Jigang Xu, Wenping Gao, Jufang Cao, Haijing Yang, Mingjun Wang, Bo Hao, Youwu Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2017
- 关键词：Environmental toxicity Pesticide Avermectin HepG2 cells Cytotoxic effects Mitochondrial-mediated apoptosis
- Characterization of Glyphosate-Induced Cardiovascular Toxicity and Apoptosis in Zebrafish Embryos被引量：49收藏
- 作者：Lu, Jian Wang, Weiguo Zhang, Cheng Xu, Wenping Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：SSRN 2022
- 关键词：Cell death - Health hazards - Herbicides
- Natural pyrethrins induces apoptosis in human hepatocyte cells via Bax- and Bcl-2-mediated mitochondrial pathway被引量：48收藏
- 作者：Yang, Yun Zong, Mimi Xu, Wenping Zhang, Yang Wang, Bo Yang, Mingjun Tao, Liming
- 机构：East China Univ Sci & Technol
- 来源：CHEMICO-BIOLOGICAL INTERACTIONS 2017
- 关键词：Natural pyrethrins Cytotoxic effects Human hepatocyte cells Apoptosis The mitochondrial pathway
- Distinct immunosuppressive effect by Isodon serra extracts被引量：47收藏
- 作者：Zhang, Y Liu, JW Jia, W Zhao, AH Li, T
- 机构：E China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：INTERNATIONAL IMMUNOPHARMACOLOGY 2005
- 关键词：immunosuppression Concanavalin A flow cytometry analyses interleukin-2
- Induction of developmental toxicity and cardiotoxicity in zebrafish embryos by Emamectin benzoate through oxidative stress被引量：46收藏
- 作者：Lu, Jian Wang, Weiguo Xu, Wenping Zhang, Chenggong Zhang, Cheng Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;Shanghai Municipal Bur Publ Secur;UT Southwestern Med Ctr
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词：Emamectin benzoate Developmental toxicity Oxidative stress Cardiotoxicity Zebrafish
- Cardiotoxicity risk induced by sanitary insecticide Dimefluthrin被引量：45收藏
- 作者：Li, Ruirui Zhou, Ning Zhang, Cheng Wu, Mengqi Xu, Wenping Cheng, Jiagao Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：Chemosphere 2024
- 关键词：Cell death - Health risks - Heart - Insecticides - Polymerase chain reaction - Risk management
- Design and synthesis of small molecular dual inhibitor of falcipain-2 and dihydrofolate reductase as antimalarial agent被引量：43收藏
- 作者：Huang, Huang Lu, Weiqiang Li, Xi Cong, Xiaoli Ma, Hongmei Liu, Xiaofeng Zhang, Yu Che, Peng Ma, Ruoqun Li, Honglin Shen, Xu Jiang, Hualiang Huang, Jin Zhu, Jin
- 机构：E China Univ Sci & Technol;Minsheng Pharma;Chinese Acad Sci
- 来源：BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2012
- 关键词：Falcipain-2 Dihydrofolate reductase Dual inhibitor Antimalarial drug SAR Molecular docking
- Difenoconazole induces oxidative DNA damage and mitochondria mediated apoptosis in SH-SY5Y cells被引量：42收藏
- 作者：Wang, Xin Ni, Hongfei Xu, Wenping Wu, Bing Xie, Te Zhang, Cheng Cheng, Jiagao Li, Zhong Tao, Liming Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：CHEMOSPHERE 2021
- 关键词：Difenoconazole Cytotoxicity DNA damage Apoptosis Human neuroblastoma SH-SY5Y cells
- Effects of Glyphosate on Zebrafish(Danio Rerio)Neural Development被引量：41收藏
- 作者：Zhou, Ning Li, Ruirui Wu, Mengqi Xu, Wenping Tao, Liming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology
- 来源：SSRN 2024
- 关键词：Animals - Gene expression - Herbicides - Pathology
- A Study on the Sex Pheromone Dispenser Application for Spodoptera Frugiperda Management on Maize被引量：39收藏
- 作者：Xu, Zhiping Wang, Xinqian Liu, Bin Zhang, Yang Xu, Wenping
- 机构： Shanghai Key Lab of Chemical Biology
- 来源：SSRN 2023
- 关键词：Bacteriology - Pest control - Water treatment
- Dimefluthrin induces female-specific reproductive toxicity in zebrafish (Danio rerio) after long-term exposure to low concentrations被引量：39收藏
- 作者：Wang, Wei-Guo Li, Rui-Rui Yang, Ming-Jun Hu, Jing-Ying Xu, Wen-Ping Tao, Li-Ming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; State Key Laboratory of Bioreactor Engineering; NHC Key Lab of Reproduction Regulation
- 来源：SSRN 2026
- 关键词：Endocrine disrupters - Endocrinology - Insecticides - Physiology - Public health - Toxicity
- Natural pyrethrins induce autophagy of HepG2 cells through the activation of AMPK/mTOR pathway被引量：38收藏
- 作者：Yang, Yun Gao, Jufang Zhang, Yang Xu, Wenping Hao, Youwu Xu, Zhiping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2018
- 关键词：Natural pyrethrins Autophagy HepG2 cells Oxidative stress AMPK/mTOR pathway
- Evaluation of the cytotoxic effects of glyphosate herbicides in human liver, lung, and nerve被引量：37收藏
- 作者：Hao, Youwu Zhang, Yang Ni, Hongfei Gao, Jufang Yang, Yun Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 2019
- 关键词：Cytotoxicity ethoxylated formulant glyphosate herbicide human health pesticide
- The effects of Spinosad on zebrafish larvae and THP-1 cells: Associated with immune cell damage and NF-kappa B signaling pathway activation被引量：37收藏
- 作者：Wang, Wei-Guo Xiong, Shou-Qian Lu, Jin Zhu, Lian-Hua Zhang, Cheng Cheng, Jia-Gao Li, Zhong Xu, Wen-Ping Tao, Li-Ming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology; Frog Prince Baby&Child Care Product Co.
- 来源：Chemosphere 2023
- 关键词：Antigen-antibody reactions - Cell signaling - Cytology - Macrophages - Signaling
- Induction of Developmental Toxicity and Cardiotoxicity in Zebrafish Embryos by Emamectin Be Nzoatethrough Oxidative Stress被引量：37收藏
- 作者：Lu, Jian Xu, Wenping Wang, Weiguo Zhang, Chenggong Zhang, Cheng Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Institute of forensic science shanghai municipal public security bureau; Department of Pathology
- 来源：SSRN 2021
- 关键词：Blood - Cell death - Toxicity - Transcription
- Roundup? confers cytotoxicity through DNA damage and Mitochondria-Associated apoptosis induction被引量：32收藏
- 作者：Hao, Youwu Chen, Hui Xu, Wenping Gao, Jufang Yang, Yun Zhang, Yang Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2019
- 关键词：Glyphosate-based herbicide Cytotoxicity DNA damage Mitochondria-associated apoptosis Human health risk
- Reversible Regulation of Succinate Dehydrogenase by Tools of Photopharmacology被引量：28收藏
- 作者：Fu, Wen Shao, Zhongli Sun, Xujuan Zhou, Cong Xu, Zhiping Zhang, Yang Cheng, Jiagao Li, Zhong Shao, Xusheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2022
- 关键词：regulation SDH photochromic ligands azobenzene optical control
- Azo-incorporating Increases Inhibitory Activity of Succinate Dehydrogenase被引量：26收藏
- 作者：Fu, Wen Hu, Xinyue Yuan, Qinglong Sun, Xujuan Xu, Zhiping Zhang, Yang Cheng, Jiagao Ye, Yonghao Li, Zhong Shao, Xusheng
- 机构：East China Univ Sci & Technol;Nanjing Agr Univ;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2021
- 关键词：azobenzene activity fungicide succinate dehydrogenase
- Discovery of a Novel CCR5 Antagonist Lead Compound Through Fragment Assembly被引量：26收藏
- 作者：Liu, Yanqing Zhou, Enkun Yu, Kunqian Zhu, Jin Zhang, Yu Xie, Xin Li, Jian Jiang, Hualiang
- 机构：Chinese Acad Sci;E China Univ Sci & Technol;Southwest Univ;Chinese Acad Sci
- 来源：MOLECULES 2008
- 关键词：CCR5 antagonist fragment assembly HIV-1 molecular modeling
- Synthesis of CF3-Containing Linear Nitriles from α-(Trifluoromethyl)styrenes被引量：26收藏
- 作者：Xu, Sixue Deng, Yupian He, Jingjing Zeng, Qanding Liu, Chuan Zhang, Yi Zhu, Bin Cao, Song
- 机构：East China Univ Sci & Technol ECUST
- 来源：ORGANIC LETTERS 2021
- DBN-Mediated Addition Reaction of α-(Trifluoromethyl)styrenes with Diazoles, Triazoles, Tetrazoles, and Primary, Secondary, and Secondary Cyclic Amines被引量：26收藏
- 作者：He, Jingjing Liu, Chuan Deng, Yupian Zeng, Qianding Zhang, Yi Liu, Ying Zheng, Pai Cao, Song
- 机构：East China Univ Sci & Technol ECUST
- 来源：ORGANIC LETTERS 2022
- Avermectin induced DNA damage to the apoptosis and autophagy in human lung epithelial A549 cells被引量：26收藏
- 作者：Diao, Lin Tang, Ning Zhang, Cheng Cheng, Jiagao Zhang, Zhenhai Wang, Siyu Wu, Can Zhang, Lutong Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2021
- 关键词：Avermectin Cytotoxicity DNA damage Programmed cell death Human A549 cells
