成果/Result
- Production of Succinate from Acetate by Metabolically Engineered Escherichia coli被引量：90收藏
- 作者：Li, Yunjie Huang, Bing Wu, Hui Li, Zhimin Ye, Qin Zhang, Y-H Percival
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Virginia Tech;Chinese Acad Sci
- 来源：ACS SYNTHETIC BIOLOGY 2016
- 关键词：acetate succinate metabolic engineering Escherichia coli malic enzyme citrate synthase
- Improved succinic acid production in the anaerobic culture of an Escherichia coli PflB ldhA double mutant as a result of enhanced anaplerotic activities in the preceding aerobic culture被引量：89收藏
- 作者：Wu, Hui Li, Zhi-Min Zhou, Li Ye, Qin
- 机构：E China Univ Chem Technol
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2007
- Systematic manipulation of glutathione metabolism in Escherichia coli for improved glutathione production被引量：85收藏
- 作者：Zhang, Jing Quan, Cong Wang, Cheng Wu, Hui Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：MICROBIAL CELL FACTORIES 2016
- 关键词：Escherichia coli Glutathione Systematic manipulation Bifunctional glutathione synthetase Fed-batch fermentation
- Simultaneous production of 3-hydroxypropionic acid and 1,3-propanediol from glycerol by a recombinant strain of Klebsiella pneumoniae被引量：84收藏
- 作者：Huang, Yanna Li, Zhimin Shimizu, Kazuyuki Ye, Qin
- 机构：E China Univ Sci & Technol;Kyushu Inst Technol
- 来源：BIORESOURCE TECHNOLOGY 2012
- 关键词：3-Hydroxypropionic acid 1,3-Propanediol Klebsiella pneumoniae Aldehyde dehydrogenase
- Co-production of 3-hydroxypropionic acid and 1,3-propanediol by Klebseilla pneumoniae expressing aldH under microaerobic conditions被引量：67收藏
- 作者：Huang, Yanna Li, Zhimin Shimizu, Kazuyuki Ye, Qin
- 机构：E China Univ Sci & Technol;Kyushu Inst Technol
- 来源：BIORESOURCE TECHNOLOGY 2013
- 关键词：3-Hydroxypropionic acid 1,3-Propanediol Klebsiella pneumoniae Aldehyde dehydrogenase Aeration
- Central pathway engineering for enhanced succinate biosynthesis from acetate in Escherichia coli被引量：62收藏
- 作者：Huang, Bing Yang, Hao Fang, Guochen Zhang, Xing Wu, Hui Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2018
- 关键词：acetate cofactor engineering Escherichia coli metabolic engineering succinate
- Development of succinic acid production from corncob hydrolysate by Actinobacillus succinogenes被引量：54收藏
- 作者：Yu, Jie Li, Zhimin Ye, Qin Yang, Yong Chen, Shulin
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2010
- 关键词：Actinobacillus succinogenes Succinic acid Corncob hydrolysate Xylose Optimization
- Catabolic regulation analysis of Escherichia coli and its crp, mlc, mgsA, pgi and ptsG mutants被引量：52收藏
- 作者：Yao, Ruilian Hirose, Yuki Sarkar, Dayanidhi Nakahigashi, Kenji Ye, Qin Shimizu, Kazuyuki
- 机构：Kyushu Inst Technol;E China Univ Sci & Technol;Keio Univ
- 来源：MICROBIAL CELL FACTORIES 2011
- Enhanced succinate production from glycerol by engineered Escherichia coli strains被引量：47收藏
- 作者：Li, Qing Wu, Hui Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCE TECHNOLOGY 2016
- 关键词：Succinate Escherichia coli Glycerol Phosphoenolpyruvate carboxykinase Two-stage fermentation
- Simultaneous saccharification and fermentation of cassava to succinic acid by Escherichia coli NZN111被引量：46收藏
- 作者：Chen, Cuixia Ding, Shaopeng Wang, Dezheng Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：Succinic acid Simultaneous saccharification and fermentation Cassava Escherichia coli NZN111
- Enhanced production of 3-hydroxypropionic acid from glucose via malonyl-CoA pathway by engineered Escherichia coli被引量：45收藏
- 作者：Cheng, Zhuan Jiang, Jiaqi Wu, Hui Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCE TECHNOLOGY 2016
- 关键词：3-Hydroxypropionate Acetyl-CoA carboxylase Malonyl-CoA reductase Corynebacterium glutamicum Escherichia coli
- L-Cysteine Production in Escherichia coli Based on Rational Metabolic Engineering and Modular Strategy被引量：43收藏
- 作者：Liu, Han Fang, Guochen Wu, Hui Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council
- 来源：BIOTECHNOLOGY JOURNAL 2018
- 关键词：Escherichia coli L-cysteine modular strategy rational metabolic engineering
- One-pot synthesis of glutathione by a two-enzyme cascade using a thermophilic ATP regeneration system被引量：43收藏
- 作者：Zhang, Xing Wu, Hui Huang, Bing Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2017
- 关键词：Glutathione Bifunctional glutathione synthetase ATP regeneration Polyphosphate Polyphosphate kinase
- Heterologous expression and characterization of a novel thermo-halotolerant endoglucanase Cel5H from Dictyoglomus thermophilum被引量：41收藏
- 作者：Shi, Runrun Li, Zhimin Ye, Qin Xu, Jianhe Liu, Yan
- 机构：E China Univ Sci & Technol;Michigan State Univ
- 来源：BIORESOURCE TECHNOLOGY 2013
- 关键词：Endoglucanase Thermostability Halo-tolerance Cellulose binding module Homology modeling
- Biosynthesis of trans-4-hydroxyproline by recombinant strains of Corynebacterium glutamicum and Escherichia coli被引量：40收藏
- 作者：Yi, Yulan Sheng, Huakai Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomanufacturing
- 来源：BMC BIOTECHNOLOGY 2014
- 关键词：Trans-4-hydroxy-L-proline Recombinant Corynebacterium glutamicum Recombinant Escherichia coli Proline 4-hydroxylases
- Enhanced 1,3-propanediol production by supply of organic acids and repeated fed-batch culture被引量：39收藏
- 作者：Xue, Xuedong Li, Wei Li, Zhimin Xia, Yuelan Ye, Qin
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2010
- 关键词：1,3-Propanediol Organic acid mixture Repeated fed-batch culture Klebsiella pneumoniae
- Production of glutathione using a bifunctional enzyme encoded by gshF from Streptococcus thermophilus expressed in Escherichia coli被引量：37收藏
- 作者：Li, Wei Li, Zhimin Yang, Jianhua Ye, Qin
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2011
- 关键词：Glutathione Bifunctional glutathione synthetase Feedback inhibition ATP regeneration system
- Serum-Free Suspension Culture of MDCK Cells for Production of Influenza H1N1 Vaccines被引量：36收藏
- 作者：Huang, Ding Peng, Wen-Juan Ye, Qian Liu, Xu-Ping Zhao, Liang Fan, Li Xia-Hou, Kang Jia, Han-Jing Luo, Jian Zhou, Lin-Ting Li, Bei-Bei Wang, Shi-Lei Xu, Wen-Ting Chen, Ze Tan, Wen-Song
- 机构：E China Univ Sci & Technol;Shanghai Inst Biol Prod Co Ltd
- 来源：PLOS ONE 2015
- Crosslinking of enzyme coaggregate with polyethyleneimine: A simple and promising method for preparing stable biocatalyst of Serratia marcescens lipase被引量：35收藏
- 作者：Pan, Jiang Kong, Xu-Dong Li, Chun-Xiu Ye, Qin Xu, Jian-He Imanaka, Tadayuki
- 机构：E China Univ Sci & Technol;Ritsumeikan Univ
- 来源：JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 2011
- 关键词：Crosslinked enzyme coaggregate Serratia marcescens lipase Polyethyleneimine Coaggregation of enzyme trans-3-(4 '-Methoxyphenyl)glycidic acid methyl ester (MPGM)
- Effects of geometrical design on hydrodynamic and mass transfer characteristics of a rectangular-column airlift bioreactor被引量：32收藏
- 作者：Kilonzo, Peter M. Margaritis, Argyrios Bergougnou, M.A. Yu, Juntang Ye, Qin
- 机构：Univ Western Ontario;E China Univ Sci & Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2007
- 关键词：airlift bioreactor clearance gas holdup liquid velocity pressure drop mass transfer
- Metabolic engineering of Escherichia coli carrying the hybrid acetone-biosynthesis pathway for efficient acetone biosynthesis from acetate被引量：32收藏
- 作者：Yang, Hao Huang, Bing Lai, Ningyu Gu, Yang Li, Zhimin Ye, Qin Wu, Hui
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council;Chinese Acad Sci
- 来源：MICROBIAL CELL FACTORIES 2019
- 关键词：Acetate Acetone Metabolic engineering Escherichia coli Gas-stripping Resting cell
- Production of succinate from simply purified crude glycerol by engineered Escherichia coli using two-stage fermentation被引量：31收藏
- 作者：Li, Qing Huang, Bing He, Qiaofei Lu, Jingxian Li, Xun Li, Zhimin Wu, Hui Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council;Nanjing Forestry Univ
- 来源：BIORESOURCES AND BIOPROCESSING 2018
- 关键词：Escherichia coli Succinate Crude glycerol Activated carbon Two-stage fermentation
- Succinic acid production and CO2 fixation using a metabolically engineered Escherichia coli in a bioreactor equipped with a self-inducing agitator被引量：28收藏
- 作者：Wu, Hui Li, Qing Li, Zhi-min Ye, Qin
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2012
- 关键词：Escherichia coli Succinic acid CO2 fixation Self-induction agitator Bioreactor
- Glutathione production by recombinant Escherichia coli expressing bifunctional glutathione synthetase被引量：27收藏
- 作者：Wang, Dezheng Wang, Cheng Wu, Hui Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2016
- 关键词：Glutathione Escherichia coli Bifunctional glutathione synthetase One-strain system Energy regeneration
- Heterologous gshF gene expression in various vector systems in Escherichia coli for enhanced glutathione production被引量：25收藏
- 作者：Wang, Cheng Zhang, Jing Wu, Hui Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2015
- 关键词：Antioxidant Glutathione Escherichia coil Bifunctional glutathione synthetase Fed-batch fermentation
- Production of succinate by a pflB ldhA double mutant of Escherichia coli overexpressing malate dehydrogenase被引量：25收藏
- 作者：Wang, Wei Li, Zhimin Xie, Jingli Ye, Qin
- 机构：E China Univ Sci & Technol
- 来源：BIOPROCESS AND BIOSYSTEMS ENGINEERING 2009
- 关键词：Escherichia coli Malate dehydrogenase Bicarbonate Succinic acid Two-stage culture
- Optimization and Scale-up of a Bioreduction Process for Preparation of Ethyl (S)-4-Chloro-3-hydroxybutanoate被引量：23收藏
- 作者：Pan, Jiang Zheng, Gao-Wei Ye, Qin Xu, Jian-He
- 机构：E China Univ Sci & Technol
- 来源：ORGANIC PROCESS RESEARCH & DEVELOPMENT 2014
- 关键词：Coenzymes
- Enhanced anaerobic succinic acid production by Escherichia coli NZN111 aerobically grown on gluconeogenic carbon sources被引量：19收藏
- 作者：Wu, Hui Li, Zhi-Min Zhou, Li Xie, Jingli Ye, Qin
- 机构：E China Univ Sci & Technol
- 来源：ENZYME AND MICROBIAL TECHNOLOGY 2009
- 关键词：Succinic acid Escherichia coli Glyconeogenic carbon source Metabolic regulation
- Transcriptomic Characterization Reveals Attributes of High Influenza Virus Productivity in MDCK Cells被引量：16收藏
- 作者：Ye, Qian Phan, Thu Hu, Wei-Shou Liu, Xuping Fan, Li Tan, Wen-Song Zhao, Liang
- 机构：East China Univ Sci & Technol;Univ Minnesota;Shanghai BioEngine Sci Tech Co Ltd
- 来源：VIRUSES-BASEL 2021
- 关键词：influenza virus MDCK cells transcriptome host shutoff anti-viral responses
- Characterization of bifunctional L-glutathione synthetases from Actinobacillus pleuropneumoniae and Actinobacillus succinogenes for efficient glutathione biosynthesis被引量：15收藏
- 作者：Yang, Jianhua Li, Wei Wang, Dezheng Wu, Hui Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Rhein Westfal TH Aachen
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2016
- 关键词：Glutathione Bifunctional glutathione synthetase Actinobacillus pleuropneumoniae Actinobacillus succinogenes Escherichia coli One-strain system
