成果/Result
- Reproductive Effects of Two Neonicotinoid Insecticides on Mouse Sperm Function and Early Embryonic Development In Vitro被引量:88收藏
- 作者:Gu, Yi-hua Li, Yan Huang, Xue-feng Zheng, Ju-fen Yang, Jun Diao, Hua Yuan, Yao Xu, Yan Liu, Miao Shi, Hui-juan Xu, Wen-ping
- 机构:Fudan Univ;Fudan Univ;Wenzhou Med Univ;E China Univ Sci & Technol
- 来源:PLOS ONE 2013
- Ivermectin induces cell cycle arrest and apoptosis of HeLa cells via mitochondrial pathway被引量:72收藏
- 作者:Zhang, Ping Zhang, Yang Liu, Kuikui Liu, Bin Xu, Wenping Gao, Jufang Ding, Lei Tao, Liming
- 机构:East China Univ Sci & Technol;Shandong Acad Pharmaceut Sci;Vegetable Tech Extens Stn Qingpu Dist Shanghai;Shanghai Normal Univ
- 来源:CELL PROLIFERATION 2019
- 关键词:antimigratory effects apoptosis cell cycle arrest cervical cancer ivermectin mitochondrial pathway
- In Vivo Visualization of γ-Glutamyl Transpeptidase Activity with an Activatable Self-Immobilizing Near-Infrared Probe被引量:56收藏
- 作者:Li, Yuyao Xue, Chenghong Fang, Zhijun Xu, Weipan Xie, Hexin
- 机构:East China Univ Sci & Technol
- 来源:ANALYTICAL CHEMISTRY 2020
- 关键词:Mammals - Quinone - Enzyme activity - Probes - Cytology - Infrared devices
- Avermectin Confers Its Cytotoxic Effects by Inducing DNA Damage and Mitochondria-Associated Apoptosis被引量:56收藏
- 作者:Zhang, Yang Luo, Mingming Xu, Wenping Yang, Mingjun Wang, Bo Gao, Jufang Li, Yaxiao Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ;Univ Bath
- 来源:JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2016
- 关键词:avermectin cytotoxic effects DNA damage apoptosis mitochondrial pathway
- Characterization of glyphosate-induced cardiovascular toxicity and apoptosis in zebrafish被引量:55收藏
- 作者:Lu, Jian Wang, Weiguo Zhang, Cheng Xu, Wenping Chen, Weidong Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构:East China Univ Sci & Technol;UT southwestern Med Ctr
- 来源:SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词:Glyphosate Developmental toxicity Heart Vascular Apoptosis Zebra fish
- Cytotoxic effects of Avermectin on human HepG2 cells in vitro bioassays被引量:51收藏
- 作者:Zhang, Yang Wu, Jigang Xu, Wenping Gao, Jufang Cao, Haijing Yang, Mingjun Wang, Bo Hao, Youwu Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ
- 来源:ENVIRONMENTAL POLLUTION 2017
- 关键词:Environmental toxicity Pesticide Avermectin HepG2 cells Cytotoxic effects Mitochondrial-mediated apoptosis
- Spinosad induces programmed cell death involves mitochondrial dysfunction and cytochrome C release in Spodoptera frugiperda Sf9 cells被引量:51收藏
- 作者:Yang, Mingjun Wang, Bo Gao, Jufang Zhang, Yang Xu, Wenping Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ
- 来源:CHEMOSPHERE 2017
- 关键词:Spinosad Programmed cell death Mitochondrial dysfunction Cytochrome C release
- Natural pyrethrins induces apoptosis in human hepatocyte cells via Bax- and Bcl-2-mediated mitochondrial pathway被引量:48收藏
- 作者:Yang, Yun Zong, Mimi Xu, Wenping Zhang, Yang Wang, Bo Yang, Mingjun Tao, Liming
- 机构:East China Univ Sci & Technol
- 来源:CHEMICO-BIOLOGICAL INTERACTIONS 2017
- 关键词:Natural pyrethrins Cytotoxic effects Human hepatocyte cells Apoptosis The mitochondrial pathway
- Induction of developmental toxicity and cardiotoxicity in zebrafish embryos by Emamectin benzoate through oxidative stress被引量:46收藏
- 作者:Lu, Jian Wang, Weiguo Xu, Wenping Zhang, Chenggong Zhang, Cheng Tao, Liming Li, Zhong Zhang, Yang
- 机构:East China Univ Sci & Technol;Shanghai Municipal Bur Publ Secur;UT Southwestern Med Ctr
- 来源:SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词:Emamectin benzoate Developmental toxicity Oxidative stress Cardiotoxicity Zebrafish
- Difenoconazole induces oxidative DNA damage and mitochondria mediated apoptosis in SH-SY5Y cells被引量:42收藏
- 作者:Wang, Xin Ni, Hongfei Xu, Wenping Wu, Bing Xie, Te Zhang, Cheng Cheng, Jiagao Li, Zhong Tao, Liming Zhang, Yang
- 机构:East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源:CHEMOSPHERE 2021
- 关键词:Difenoconazole Cytotoxicity DNA damage Apoptosis Human neuroblastoma SH-SY5Y cells
- Natural pyrethrins induce autophagy of HepG2 cells through the activation of AMPK/mTOR pathway被引量:38收藏
- 作者:Yang, Yun Gao, Jufang Zhang, Yang Xu, Wenping Hao, Youwu Xu, Zhiping Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ
- 来源:ENVIRONMENTAL POLLUTION 2018
- 关键词:Natural pyrethrins Autophagy HepG2 cells Oxidative stress AMPK/mTOR pathway
- Evaluation of the cytotoxic effects of glyphosate herbicides in human liver, lung, and nerve被引量:37收藏
- 作者:Hao, Youwu Zhang, Yang Ni, Hongfei Gao, Jufang Yang, Yun Xu, Wenping Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ
- 来源:JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 2019
- 关键词:Cytotoxicity ethoxylated formulant glyphosate herbicide human health pesticide
- Roundup? confers cytotoxicity through DNA damage and Mitochondria-Associated apoptosis induction被引量:32收藏
- 作者:Hao, Youwu Chen, Hui Xu, Wenping Gao, Jufang Yang, Yun Zhang, Yang Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ
- 来源:ENVIRONMENTAL POLLUTION 2019
- 关键词:Glyphosate-based herbicide Cytotoxicity DNA damage Mitochondria-associated apoptosis Human health risk
- The Association between Exposure to Environmental Bisphenol A and Gonadotropic Hormone Levels among Men被引量:26收藏
- 作者:Liang, Hong Xu, Wenping Chen, Jianping Shi, Huijuan Zhu, Jiang Liu, Xiaoqin Wang, Jian Miao, Maohua Yuan, Wei
- 机构:Fudan Univ;East China Univ Sci & Technol;Fudan Univ;Populat & Family Planning Inst Guizhou Prov;Aarhus Univ
- 来源:PLOS ONE 2017
- Exposure to environmental concentrations of natural pyrethrins induces hepatotoxicity: Assessment in HepG2 cell lines and zebrafish models被引量:25收藏
- 作者:Lu, Jian Yang, Yun Zhu, Lianhua Li, Meng Xu, Wenping Zhang, Cheng Cheng, Jiagao Tao, Liming Li, Zhong Zhang, Yang
- 机构:East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源:CHEMOSPHERE 2022
- 关键词:Natural pyrethrins Hepatotoxicity Oxidative stress DNA damage Repair HepG2 cells Zebrafish
- Pyrethrum-extract induced autophagy in insect cells: A new target?被引量:21收藏
- 作者:Xu, Zhiping Lu, Miaoqing Yang, Mingjun Xu, Wenping Gao, Jufang Zhang, Yang Yang, Yun Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ
- 来源:PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 2017
- 关键词:Insecticide Pyrethrum-extract Sf9 cells Cytotoxicity Autophagy
- Staurosporine shows insecticidal activity against Mythimna separata Walker (Lepidoptera: Noctuidae) potentially via induction of apoptosis被引量:21收藏
- 作者:Zhang, Yang Liu, Songlin Yang, Xing Yang, Mingjun Xu, Wenping Li, Yaxiao Tao, Liming
- 机构:E China Univ Sci & Technol;Shanghai Pesticide Res Inst;Univ Bath
- 来源:PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 2016
- 关键词:Insecticidal activity Staurosporine Mythimna separata Walker Apoptosis Sf9 cells The mitochondrial pathway
- Spinosad induces autophagy of Spodoptera frugiperda Sf9 cells and the activation of AMPK/mTOR signaling pathway被引量:21收藏
- 作者:Yang, Mingjun Hao, Youwu Gao, Jufang Zhang, Yang Xu, Wenping Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ
- 来源:COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY 2017
- 关键词:Spinosad Sf9 cells Autophagy AMPK mTOR
- The insecticide spinosad induces DNA damage and apoptosis in HEK293 and HepG2 cells被引量:21收藏
- 作者:Yang, Mingjun Xiang, Guanggang Li, Diqiu Zhang, Yang Xu, Wenping Tao, Liming
- 机构:East China Univ Sci & Technol
- 来源:MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 2016
- 关键词:Spinosad DNA damage Comet assay H2AX foci Apoptosis Cytotoxic
- Spinetoram confers its cytotoxic effects by inducing AMPK/mTOR-mediated autophagy and oxidative DNA damage被引量:21收藏
- 作者:Zhang, Yang Guo, Wei Chen, Hui Gao, Jufang Xu, Zhiping Tao, Liming Li, Zhong Xu, Wenping
- 机构:East China Univ Sci & Technol;China Crop Protect Ind Assoc;Shanghai Normal Univ
- 来源:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2019
- 关键词:Spinetoram Cytotoxic effects Mitochondrial dysfunction AMPK/mTOR-mediated autophagy Oxidative DNA damage
- Ivermectin confers its cytotoxic effects by inducing AMPK/mTOR-mediated autophagy and DNA damage被引量:20收藏
- 作者:Zhang, Ping Ni, Hongfei Zhang, Yang Xu, Wenping Gao, Jufang Cheng, Jiagao Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ
- 来源:CHEMOSPHERE 2020
- 关键词:Ivermectin Accumulated toxicity Cytotoxicity DNA damage Autophagy
- Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells被引量:20收藏
- 作者:Xu, Wenping Wang, Bo Yang, Mingjun Zhang, Yang Xu, Zhiping Yang, Yun Cao, Haijing Tao, Liming
- 机构:East China Univ Sci & Technol
- 来源:ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 2017
- 关键词:Pesticide Tebufenozide Cytotoxic effects DNA damage Cell cycle arrest Apoptosis
- Oxidative stress and DNA damage induced by spinosad exposure in Spodoptera frugiperda Sf9 cells被引量:19收藏
- 作者:Xu, Wenping Yang, Mingjun Gao, Jufang Zhang, Yang Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Inst Planned Parenthood Res;Shanghai Normal Univ
- 来源:FOOD AND AGRICULTURAL IMMUNOLOGY 2018
- 关键词:Oxidative stress DNA damage spinosad sf9 cells
- Potential threat of Chlorpyrifos to human liver cells via the caspase-dependent mitochondrial pathways被引量:19收藏
- 作者:Zhang, Yang Chang, Yuansen Cao, Haijing Xu, Wenping Li, Zhong Tao, Liming
- 机构:East China Univ Sci & Technol
- 来源:FOOD AND AGRICULTURAL IMMUNOLOGY 2018
- 关键词:Pesticide Chlorpyrifos human liver cells cytotoxic effects the mitochondrial apoptosis pathway
- Adjuvant contributes Roundup's unexpected effects on A549 cells被引量:18收藏
- 作者:Hao, Youwu Zhang, Yang Cheng, Jiagao Xu, Wenping Xu, Zhiping Gao, Jufang Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ
- 来源:ENVIRONMENTAL RESEARCH 2020
- 关键词:Roundup Adjuvant Apoptosis DNA damage POEA
- Roundup-Induced AMPK/mTOR-Mediated Autophagy in Human A549 Cells被引量:18收藏
- 作者:Hao, Youwu Xu, Wenping Gao, Jufang Zhang, Yang Yang, Yun Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ
- 来源:JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词:Roundup adjuvant POEA glyphosate isopropylamine salt A549 cells autophagy
- Developmental and cardiovascular toxicities of acetochlor and its chiral isomers in zebrafish embryos through oxidative stress被引量:17收藏
- 作者:Wang, Xin Chen, Fan Lu, Jian Wu, Mengqi Cheng, Jiagao Xu, Wenping Li, Zhong Zhang, Yang
- 机构:East China Univ Sci & Technol
- 来源:SCIENCE OF THE TOTAL ENVIRONMENT 2023
- 关键词:Acetochlor Zebrafish Chiral isomers Developmental toxicity Cardiovascular toxicity
- The enantioselective study of the toxicity effects of chiral acetochlor in HepG2 cells被引量:17收藏
- 作者:Wang, Susu Zhang, Yang Gao, Jufang Zhang, Jingdi Tao, Liming Xu, Wenping
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ;Kao Chem Corp Shanghai
- 来源:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2021
- 关键词:Acetochlor Enantiomers Cytotoxicity Apoptosis HepG2 cells
- Cytotoxic effects of bio-pesticide spinosad on human lung A549 cells被引量:17收藏
- 作者:Zhang, Yang Chen, Hui Fan, Yangyang Yang, Yun Gao, Jufang Xu, Wenping Xu, Zhiping Li, Zhong Tao, Liming
- 机构:East China Univ Sci & Technol;Shanghai Normal Univ
- 来源:CHEMOSPHERE 2019
- 关键词:Spinosad Cytotoxicity DNA damage Human epithelial A549 lung cells AMPK/mTOR-mediated autophagy
- Exposure to environmental concentrations of glyphosate induces cardiotoxicity through cellular senescence and reduced cell proliferation capacity被引量:16收藏
- 作者:Lu, Jian Zhang, Cheng Wang, Weiguo Xu, Wenping Chen, Weidong Tao, Liming Li, Zhong Zhang, Yang Cheng, Jiagao
- 机构:East China Univ Sci & Technol;UT southwestern Med Ctr
- 来源:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2023
- 关键词:Glyphosate AC16 Senescence Cardiomyocyte proliferation Endoplasmic reticulum
