- Spatiotemporal control of gene expression by a light-switchable transgene system被引量：406收藏
- 作者：Wang, Xue Chen, Xianjun Yang, Yi
- 机构：E China Univ Sci & Technol
- 来源：NATURE METHODS 2012
- 质疑
- SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents被引量：321收藏
- 作者：Zhao, Yuzheng Hu, Qingxun Cheng, Feixiong Su, Ni Wang, Aoxue Zou, Yejun Hu, Hanyang Chen, Xianjun Zhou, Hai-Meng Huang, Xinzhi Yang, Kai Zhu, Qian Wang, Xue Yi, Jing Zhu, Linyong Qian, Xuhong Chen, Lixin Tang, Yun Loscalzo, Joseph Yang, Yi
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Tsinghua Univ
- 来源：CELL METABOLISM 2015
- 质疑
- Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism被引量：269收藏
- 作者：Tao, Rongkun Zhao, Yuzheng Chu, Huanyu Wang, Aoxue Zhu, Jiahuan Chen, Xianjun Zou, Yejun Shi, Mei Liu, Renmei Su, Ni Du, Jiulin Zhou, Hai-Meng Zhu, Linyong Qian, Xuhong Liu, Haiyan Loscalzo, Joseph Yang, Yi
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;Univ Sci & Technol China;Tsinghua Univ
- 来源：NATURE METHODS 2017
- 质疑
- Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs被引量：249收藏
- 作者：Chen, Xianjun Zhang, Dasheng Su, Ni Bao, Bingkun Xie, Xin Zuo, Fangting Yang, Lipeng Wang, Hui Jiang, Li Lin, Qiuning Fang, Mengyue Li, Ningfeng Hua, Xin Chen, Zhengda Bao, Chunyan Xu, Jinjin Du, Wenli Zhang, Lixin Zhao, Yuzheng Zhu, Linyong Loscalzo, Joseph Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：NATURE BIOTECHNOLOGY 2019
- 关键词：Cells - Enzyme kinetics - Fluorescence - Mammals - Cytology
- 质疑
- Ultrasensitive sensors reveal the spatiotemporal landscape of lactate metabolism in physiology and disease被引量：106收藏
- 作者：Li, Xi Zhang, Yinan Xu, Lingya Wang, Aoxue Zou, Yejun Li, Ting Huang, Li Chen, Weicai Liu, Shuning Jiang, Kun Zhang, Xiuze Wang, Dongmei Zhang, Lijuan Zhang, Zhuo Zhang, Zeyi Chen, Xianjun Jia, Wei Zhao, Aihua Yan, Xinfeng Zhou, Haimeng Zhu, Linyong Ma, Xinran Ju, Zhenyu Jia, Weiping Wang, Congrong Loscalzo, Joseph Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;Chinese Acad Med Sci;Chinese Acad Sci;Shanghai Jiao Tong Univ Affiliated Peoples Hosp 6;East China Normal Univ
- 来源：CELL METABOLISM 2023
- 质疑
- Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor被引量：95收藏
- 作者：Zou, Yejun Wang, Aoxue Huang, Li Zhu, Xudong Hu, Qingxun Zhang, Yinan Chen, Xianjun Li, Fengwen Wang, Qiaohui Wang, Hu Liu, Renmei Zuo, Fangting Li, Ting Yao, Jing Qian, Yajin Shi, Mei Yue, Xiao Chen, Weicai Zhang, Zhuo Wang, Congrong Zhou, Yong Zhu, Linyong Ju, Zhenyu Loscalzo, Joseph Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;Hangzhou Normal Univ;Shanghai Jiao Tong Univ
- 来源：DEVELOPMENTAL CELL 2020
- 质疑
- Analysis of redox landscapes and dynamics in living cells and in vivo using genetically encoded fluorescent sensors被引量：83收藏
- 作者：Zou, Yejun Wang, Aoxue Shi, Mei Chen, Xianjun Liu, Renmei Li, Ting Zhang, Chenxia Zhang, Zhuo Zhu, Linyong Ju, Zhenyu Loscalzo, Joseph Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Jinan Univ;Harvard Med Sch
- 来源：NATURE PROTOCOLS 2018
- 质疑
- Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins被引量：60收藏
- 作者：Liu, Renmei Yang, Jing Yao, Jing Zhao, Zhou He, Wei Su, Ni Zhang, Zeyi Zhang, Chenxia Zhang, Zhuo Cai, Haibo Zhu, Linyong Zhao, Yuzheng Quan, Shu Chen, Xianjun Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：NATURE BIOTECHNOLOGY 2022
- 关键词：Proteins - Cell culture
- 质疑
- Large Stokes shift fluorescent RNAs for dual-emission fluorescence and bioluminescence imaging in live cells被引量：58收藏
- 作者：Jiang, Li Xie, Xin Su, Ni Zhang, Dasheng Chen, Xianjun Xu, Xiaochen Zhang, Bibi Huang, Kaiyi Yu, Jingwei Fang, Mengyue Bao, Bingkun Zuo, Fangting Yang, Lipeng Zhang, Rui Li, Huiwen Huang, Xinyi Chen, Zhengda Zeng, Qingmei Liu, Renmei Lin, Qiuning Zhao, Yuzheng Ren, Aiming Zhu, Linyong Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Fluorescence Diag Shanghai Biotech Co Ltd;Zhejiang Univ
- 来源：NATURE METHODS 2023
- 质疑
- A single-component light sensor system allows highly tunable and direct activation of gene expression in bacterial cells被引量：52收藏
- 作者：Li, Xie Zhang, Changcheng Xu, Xiaopei Miao, Jun Yao, Jing Liu, Renmei Zhao, Yuzheng Chen, Xianjun Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol
- 来源：NUCLEIC ACIDS RESEARCH 2020
- 质疑
- Imaging the dynamics of messenger RNA with a bright and stable green fluorescent RNA被引量：42收藏
- 作者：Zuo, Fangting Jiang, Li Su, Ni Zhang, Yaqiang Bao, Bingkun Wang, Limei Shi, Yajie Yang, Huimin Huang, Xinyi Li, Ruilong Zeng, Qingmei Chen, Zhengda Lin, Qiuning Zhuang, Yingping Zhao, Yuzheng Chen, Xianjun Zhu, Linyong Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;East China Univ Sci & Technol;Chinese Acad Med Sci
- 来源：NATURE CHEMICAL BIOLOGY 2024
- 质疑
- Synthetic dual-input mammalian genetic circuits enable tunable and stringent transcription control by chemical and light被引量：36收藏
- 作者：Chen, Xianjun Li, Ting Wang, Xue Du, Zengmin Liu, Renmei Yang, Yi
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：NUCLEIC ACIDS RESEARCH 2016
- 质疑
- Glucose monitoring in living cells with single fluorescent protein-based sensors被引量：36收藏
- 作者：Hu, Hanyang Wei, Yufeng Wang, Daocheng Su, Ni Chen, Xianjun Zhao, Yuzheng Liu, Guixia Yang, Yi
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol
- 来源：RSC ADVANCES 2018
- 关键词：Proteins - Escherichia coli - Cells - Cytology - Fluorescence - Metabolism - Glucose sensors
- 质疑
- A Single-Component Optogenetic System Allows Stringent Switch of Gene Expression in Yeast Cells被引量：35收藏
- 作者：Xu, Xiaopei Du, Zhaoxia Liu, Renmei Li, Ting Zhao, Yuzheng Chen, Xianjun Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：ACS SYNTHETIC BIOLOGY 2018
- 关键词：yeast optogenetic gene expression protein stability
- 质疑
- A synthetic BRET-based optogenetic device for pulsatile transgene expression enabling glucose homeostasis in mice被引量：34收藏
- 作者：Li, Ting Chen, Xianjun Qian, Yajie Shao, Jiawei Li, Xie Liu, Shuning Zhu, Linyong Zhao, Yuzheng Ye, Haifeng Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;East China Normal Univ;East China Normal Univ
- 来源：NATURE COMMUNICATIONS 2021
- 质疑
- Fine tuning the LightOn light-switchable transgene expression system被引量：33收藏
- 作者：Ma, Zhengcai Du, Zengmin Chen, Xianjun Wang, Xue Yang, Yi
- 机构：E China Univ Sci & Technol
- 来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2013
- 关键词：Gene expression Light Induction efficiency Background expression
- 质疑
- A genetically encoded toolkit for tracking live-cell histidine dynamics in space and time被引量：32收藏
- 作者：Hu, Hanyang Gu, Yanfang Xu, Lei Zou, Yejun Wang, Aoxue Tao, Rongkun Chen, Xianjun Zhao, Yuzheng Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：SCIENTIFIC REPORTS 2017
- 质疑
- Spatiotemporally controllable diphtheria toxin expression using a light-switchable transgene system combining multifunctional nanoparticle delivery system for targeted melanoma therapy被引量：28收藏
- 作者：He, Muye Wang, Yan Chen, Xianjun Zhao, Yuzheng Lou, Kaiyan Wang, Yujie Huang, Lei Hou, Xinyu Xu, Jiajun Cai, Xiaoran Cheng, Yi Lan, Minbo Yang, Yi Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF CONTROLLED RELEASE 2020
- 关键词：Light-switchable gene expression Diphtheria toxin Melanoma Nanoparticle delivery system
- 质疑
- Design of a palette of SNAP-tag mimics of fluorescent proteins and their use as cell reporters被引量：23收藏
- 作者：Zhang, Dasheng Chen, Zhengda Du, Zengmin Bao, Bingkun Su, Ni Chen, Xianjun Ge, Yihui Lin, Qiuning Yang, Lipeng Hua, Yujie Wang, Shuo Hua, Xin Zuo, Fangting Li, Ningfeng Liu, Renmei Jiang, Li Bao, Chunyan Zhao, Yuzheng Loscalzo, Joseph Yang, Yi Zhu, Linyong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Harvard Med Sch
- 来源：CELL DISCOVERY 2023
- 质疑
- Monitoring cellular redox state under hypoxia using a fluorescent sensor based on eel fluorescent protein被引量：22收藏
- 作者：Hu, Hanyang Wang, Aoxue Huang, Li Zou, Yejun Gu, Yanfang Chen, Xianjun Zhao, Yuzheng Yang, Yi
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol
- 来源：FREE RADICAL BIOLOGY AND MEDICINE 2018
- 关键词：Eel fluorescent protein UnaG Redox state Real-time monitoring RoUnaG Oxygen-independent Hypoxia
- 质疑
- Light-induced protein degradation in human-derived cells被引量：21收藏
- 作者：Sun, Wansheng Zhang, Wenyao Zhang, Chao Mao, Miaowei Zhao, Yuzheng Chen, Xianjun Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2017
- 关键词：Light Protein degradation Light-switchable degron
- 质疑
- Lighting up arginine metabolism reveals itsfunctional diversity in physiology and pathology被引量：21收藏
- 作者：Li, Rui Li, Yan Jiang, Kun Zhang, Lijuan Li, Ting Zhao, Aihua Zhang, Zhuo Xia, Yale Ge, Kun Chen, Yaqiong Wang, Chengnuo Tang, Weitao Liu, Shuning Lin, Xiaoxi Song, Yuqin Mei, Jie Xiao, Chun Wang, Aoxue Zou, Yejun Li, Xie Chen, Xianjun Ju, Zhenyu Jia, Wei Loscalzo, Joseph Sun, Yu Fang, Wei Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;Chinese Acad Med Sci;Univ Chinese Acad Sci;Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ
- 来源：CELL METABOLISM 2025
- 质疑
- MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells被引量：20收藏
- 作者：Gu, Hao Chen, Chiqi Hao, Xiaoxin Su, Ni Huang, Dan Zou, Yejun Lin, Shu-Hai Chen, Xianjun Zheng, Denghao Liu, Ligen Yu, Zhuo Xie, Li Zhang, Yaping He, Xiaoxiao Lai, Xiaoyun Zhang, Xiaocui Chen, Guo-Qiang Zhao, Yuzheng Yang, Yi Loscalzo, Joseph Zheng, Junke
- 机构：Shanghai Jiao Tong Univ;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Chinese Acad Sci;Harvard Med Sch
- 来源：BLOOD 2020
- 质疑
- Structural basis of a small monomeric Clivia fluorogenic RNA with a large Stokes shift被引量：18收藏
- 作者：Huang, Kaiyi Song, Qianqian Fang, Mengyue Yao, Deqiang Shen, Xin Xu, Xiaochen Chen, Xianjun Zhu, Linyong Yang, Yi Ren, Aiming
- 机构：Zhejiang Univ;Zhejiang Univ;East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：NATURE CHEMICAL BIOLOGY 2024
- 质疑
- Imaging intracellular metabolite and protein changes in live mammalian cells with bright fluorescent RNA-based genetically encoded sensors被引量：17收藏
- 作者：Fang, Mengyue Li, Huiwen Xie, Xin Wang, Hui Jiang, Ying Li, Tianyu Zhang, Bibi Jiang, Xin Cao, Yueyang Zhang, Rui Zhang, Dasheng Zhao, Yuzheng Zhu, Linyong Chen, Xianjun Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：BIOSENSORS & BIOELECTRONICS 2023
- 关键词：Genetically encoded sensor Fluorogenic RNA aptamer Pepper Metabolite and protein dynamics
- 质疑
- Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy被引量：16收藏
- 作者：Cheng, Yi Zou, Jiafeng He, Muye Hou, Xinyu Wang, Hongtao Xu, Jiajun Yuan, Zeting Lan, Minbo Yang, Yi Chen, Xianjun Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF CONTROLLED RELEASE 2024
- 关键词：Spatiotemporally controlled gene expression cancer -associated fibroblasts Multifunctional nanoparticles Pseudomonas exotoxin A Antimetastasis therapy Breast cancer
- 质疑
- A Single-Component Optogenetic Gal4-UAS System Allows Stringent Control of Gene Expression in Zebrafish and Drosophila被引量：15收藏
- 作者：Qian, Yajie Li, Ting Zhou, Siyu Chen, Xianjun Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS SYNTHETIC BIOLOGY 2023
- 关键词：optogenetics single-component gene expression Gal4-UAS
- 质疑
- A light-switchable bidirectional expression module allowing simultaneous regulation of multiple genes被引量：10收藏
- 作者：Chen, Xianjun Li, Ting Wang, Xue Yang, Yi
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2015
- 关键词：Bidirectional Gene expression Light Simultaneous regulation
- 质疑
- Structure-function analysis of human protein Ero1-Lα被引量：9收藏
- 作者：Chu, Yanyan Yang, Charles Chen, Xianjun Zheng, Wenyun Yang, Yi Tang, Yun
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2009
- 关键词：Disulfide bond Ero1-L alpha Thioredoxin Homology modeling Structure-function analysis
- 质疑
- Light-switchable diphtherin transgene system combined with losartan for triple negtative breast cancer therapy based on nano drug delivery system被引量：8收藏
- 作者：Cheng, Yi Sun, Rui He, Muye Zhang, Miao Hou, Xinyu Sun, Yuji Wang, Jie Xu, Jiajun He, Hai Wang, Hongtao Lan, Minbo Zhao, Yuzheng Yang, Yi Chen, Xianjun Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Med Sci
- 来源：INTERNATIONAL JOURNAL OF PHARMACEUTICS 2022
- 关键词：Light-switchable diphtherin transgene system Losartan Tumor microenvironment Breast cancer Nanoparticle drug delivery system
- 质疑
