成果/Result
- The organophosphate insecticide chlorpyrifos confers its genotoxic effects by inducing DNA damage and cell apoptosis被引量：95收藏
- 作者：Li, Diqiu Huang, Qingchun Lu, Miaoqing Zhang, Lei Yang, Zhichuan Zong, Mimi Tao, Liming
- 机构：E China Univ Sci & Technol
- 来源：CHEMOSPHERE 2015
- 关键词：Chlorpyrifos Genotoxicity DNA damage Cell apoptosis H2AX foci
- Carbamate insecticide methomyl confers cytotoxicity through DNA damage induction被引量：80收藏
- 作者：Xiang Guanggang Li Diqiu Yuan Jianzhong Guan Jingmin Zhai Huifeng Shi Mingan Tao Liming
- 机构：E China Univ Sci & Technol;Chinese Acad Sci;Yangzhou Univ
- 来源：FOOD AND CHEMICAL TOXICOLOGY 2013
- 关键词：Methomyl DNA damage Apoptosis Alkaline comet assay gamma H2AX foci DNA fragmentation
- Ivermectin induces cell cycle arrest and apoptosis of HeLa cells via mitochondrial pathway被引量：72收藏
- 作者：Zhang, Ping Zhang, Yang Liu, Kuikui Liu, Bin Xu, Wenping Gao, Jufang Ding, Lei Tao, Liming
- 机构：East China Univ Sci & Technol;Shandong Acad Pharmaceut Sci;Vegetable Tech Extens Stn Qingpu Dist Shanghai;Shanghai Normal Univ
- 来源：CELL PROLIFERATION 2019
- 关键词：antimigratory effects apoptosis cell cycle arrest cervical cancer ivermectin mitochondrial pathway
- Effects of Glyphosate on Zebrafish (Danio rerio) Developmental Toxicity被引量：63收藏
- 作者：Zhou, Ning Li, Ruirui Lu, Jin Cheng, Jiagao Xu, Wenping Tao, Liming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Frog Prince Baby & Child Care Product Co. Ltd.
- 来源：Environmental Toxicology 2025
- 关键词：Aquatic organisms - Herbicides - Weed control
- Characterization of hepatotoxic effects induced by pyraclostrobin in human HepG2 cells and zebrafish larvae被引量：60收藏
- 作者：Wu, Mengqi Bian, Jinhao Han, Shuang Zhang, Cheng Xu, Wenping Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology; State Key Laboratory of Bioreactor Engineering
- 来源：Chemosphere 2023
- 关键词：Activation analysis - Disease control - Mitochondria
- Developmental toxicity and estrogenicity of glyphosate in zebrafish in vivo and in silico studies被引量：58收藏
- 作者：Lu, Jian Zhang, Cheng Xu, Wenping Chen, Weidong Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：Chemosphere 2023
- 关键词：Animals - Deep learning - Endocrine disrupters - Herbicides
- Avermectin Confers Its Cytotoxic Effects by Inducing DNA Damage and Mitochondria-Associated Apoptosis被引量：56收藏
- 作者：Zhang, Yang Luo, Mingming Xu, Wenping Yang, Mingjun Wang, Bo Gao, Jufang Li, Yaxiao Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ;Univ Bath
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2016
- 关键词：avermectin cytotoxic effects DNA damage apoptosis mitochondrial pathway
- Characterization of glyphosate-induced cardiovascular toxicity and apoptosis in zebrafish被引量：55收藏
- 作者：Lu, Jian Wang, Weiguo Zhang, Cheng Xu, Wenping Chen, Weidong Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构：East China Univ Sci & Technol;UT southwestern Med Ctr
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词：Glyphosate Developmental toxicity Heart Vascular Apoptosis Zebra fish
- Cytotoxic effects of Avermectin on human HepG2 cells in vitro bioassays被引量：51收藏
- 作者：Zhang, Yang Wu, Jigang Xu, Wenping Gao, Jufang Cao, Haijing Yang, Mingjun Wang, Bo Hao, Youwu Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2017
- 关键词：Environmental toxicity Pesticide Avermectin HepG2 cells Cytotoxic effects Mitochondrial-mediated apoptosis
- Spinosad induces programmed cell death involves mitochondrial dysfunction and cytochrome C release in Spodoptera frugiperda Sf9 cells被引量：51收藏
- 作者：Yang, Mingjun Wang, Bo Gao, Jufang Zhang, Yang Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：CHEMOSPHERE 2017
- 关键词：Spinosad Programmed cell death Mitochondrial dysfunction Cytochrome C release
- Characterization of Glyphosate-Induced Cardiovascular Toxicity and Apoptosis in Zebrafish Embryos被引量：49收藏
- 作者：Lu, Jian Wang, Weiguo Zhang, Cheng Xu, Wenping Tao, Liming Li, Zhong Cheng, Jiagao Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：SSRN 2022
- 关键词：Cell death - Health hazards - Herbicides
- Natural pyrethrins induces apoptosis in human hepatocyte cells via Bax- and Bcl-2-mediated mitochondrial pathway被引量：48收藏
- 作者：Yang, Yun Zong, Mimi Xu, Wenping Zhang, Yang Wang, Bo Yang, Mingjun Tao, Liming
- 机构：East China Univ Sci & Technol
- 来源：CHEMICO-BIOLOGICAL INTERACTIONS 2017
- 关键词：Natural pyrethrins Cytotoxic effects Human hepatocyte cells Apoptosis The mitochondrial pathway
- Induction of developmental toxicity and cardiotoxicity in zebrafish embryos by Emamectin benzoate through oxidative stress被引量：46收藏
- 作者：Lu, Jian Wang, Weiguo Xu, Wenping Zhang, Chenggong Zhang, Cheng Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;Shanghai Municipal Bur Publ Secur;UT Southwestern Med Ctr
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2022
- 关键词：Emamectin benzoate Developmental toxicity Oxidative stress Cardiotoxicity Zebrafish
- Cardiotoxicity risk induced by sanitary insecticide Dimefluthrin被引量：45收藏
- 作者：Li, Ruirui Zhou, Ning Zhang, Cheng Wu, Mengqi Xu, Wenping Cheng, Jiagao Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology
- 来源：Chemosphere 2024
- 关键词：Cell death - Health risks - Heart - Insecticides - Polymerase chain reaction - Risk management
- Effects of sublethal concentrations of the chitin synthesis inhibitor, hexaflumuron, on the development and hemolymph physiology of the cutworm, Spodoptera litura被引量：44收藏
- 作者：Zhu, Qiqi He, Yuan Yao, Jing Liu, Yinzhao Tao, Liming Huang, Qingchun
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF INSECT SCIENCE 2012
- 关键词：sublethal effects hexaflumuron Spodoptera litura
- Difenoconazole induces oxidative DNA damage and mitochondria mediated apoptosis in SH-SY5Y cells被引量：42收藏
- 作者：Wang, Xin Ni, Hongfei Xu, Wenping Wu, Bing Xie, Te Zhang, Cheng Cheng, Jiagao Li, Zhong Tao, Liming Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：CHEMOSPHERE 2021
- 关键词：Difenoconazole Cytotoxicity DNA damage Apoptosis Human neuroblastoma SH-SY5Y cells
- Effects of Glyphosate on Zebrafish(Danio Rerio)Neural Development被引量：41收藏
- 作者：Zhou, Ning Li, Ruirui Wu, Mengqi Xu, Wenping Tao, Liming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology
- 来源：SSRN 2024
- 关键词：Animals - Gene expression - Herbicides - Pathology
- Dimefluthrin induces female-specific reproductive toxicity in zebrafish (Danio rerio) after long-term exposure to low concentrations被引量：39收藏
- 作者：Wang, Wei-Guo Li, Rui-Rui Yang, Ming-Jun Hu, Jing-Ying Xu, Wen-Ping Tao, Li-Ming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; State Key Laboratory of Bioreactor Engineering; NHC Key Lab of Reproduction Regulation
- 来源：SSRN 2026
- 关键词：Endocrine disrupters - Endocrinology - Insecticides - Physiology - Public health - Toxicity
- Natural pyrethrins induce autophagy of HepG2 cells through the activation of AMPK/mTOR pathway被引量：38收藏
- 作者：Yang, Yun Gao, Jufang Zhang, Yang Xu, Wenping Hao, Youwu Xu, Zhiping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2018
- 关键词：Natural pyrethrins Autophagy HepG2 cells Oxidative stress AMPK/mTOR pathway
- Evaluation of the cytotoxic effects of glyphosate herbicides in human liver, lung, and nerve被引量：37收藏
- 作者：Hao, Youwu Zhang, Yang Ni, Hongfei Gao, Jufang Yang, Yun Xu, Wenping Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES 2019
- 关键词：Cytotoxicity ethoxylated formulant glyphosate herbicide human health pesticide
- The effects of Spinosad on zebrafish larvae and THP-1 cells: Associated with immune cell damage and NF-kappa B signaling pathway activation被引量：37收藏
- 作者：Wang, Wei-Guo Xiong, Shou-Qian Lu, Jin Zhu, Lian-Hua Zhang, Cheng Cheng, Jia-Gao Li, Zhong Xu, Wen-Ping Tao, Li-Ming Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Department of Pathology; Frog Prince Baby&Child Care Product Co.
- 来源：Chemosphere 2023
- 关键词：Antigen-antibody reactions - Cell signaling - Cytology - Macrophages - Signaling
- Induction of Developmental Toxicity and Cardiotoxicity in Zebrafish Embryos by Emamectin Be Nzoatethrough Oxidative Stress被引量：37收藏
- 作者：Lu, Jian Xu, Wenping Wang, Weiguo Zhang, Chenggong Zhang, Cheng Tao, Liming Li, Zhong Zhang, Yang
- 机构： Shanghai Key Laboratory of Chemical Biology; Institute of forensic science shanghai municipal public security bureau; Department of Pathology
- 来源：SSRN 2021
- 关键词：Blood - Cell death - Toxicity - Transcription
- Detection on emamectin benzoate-induced apoptosis and DNA damage in Spodoptera frugiperda Sf-9 cell line被引量：35收藏
- 作者：Wu, Xiwei Zhang, Lei Yang, Chao Zong, Mimi Huang, Qingchun Tao, Liming
- 机构：E China Univ Sci & Technol
- 来源：PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 2016
- 关键词：Emamectin benzoate Sf-9 cells Cytotoxicity DNA damage Apoptosis
- Synthesis, Crystal Structure, and Insecticidal Activities of Highly Congested Hexahydroimidazo[1,2-a]pyridine Derivatives: Effect of Conformation on Activities被引量：35收藏
- 作者：Shao, Xusheng Xu, Zhiping Zhao, Xianfeng Xu, Xiaoyong Tao, Limin Zhong Li Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2010
- 关键词：Diels-Alder reaction insecticide conformation activities
- Synergistic effect of non-ionic surfactants Tween 80 and PEG6000 on cytotoxicity of insecticides被引量：33收藏
- 作者：Li, Diqiu Wu, Xiwei Yu, Xiaoqin Huang, Qingchun Tao, Liming
- 机构：E China Univ Sci & Technol
- 来源：ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 2015
- 关键词：Tween 80 PEG6000 Insecticides Cytotoxicity Synergistic effect
- Roundup? confers cytotoxicity through DNA damage and Mitochondria-Associated apoptosis induction被引量：32收藏
- 作者：Hao, Youwu Chen, Hui Xu, Wenping Gao, Jufang Yang, Yun Zhang, Yang Tao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ENVIRONMENTAL POLLUTION 2019
- 关键词：Glyphosate-based herbicide Cytotoxicity DNA damage Mitochondria-associated apoptosis Human health risk
- Avermectin induced DNA damage to the apoptosis and autophagy in human lung epithelial A549 cells被引量：26收藏
- 作者：Diao, Lin Tang, Ning Zhang, Cheng Cheng, Jiagao Zhang, Zhenhai Wang, Siyu Wu, Can Zhang, Lutong Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2021
- 关键词：Avermectin Cytotoxicity DNA damage Programmed cell death Human A549 cells
- Exposure to environmental concentrations of natural pyrethrins induces hepatotoxicity: Assessment in HepG2 cell lines and zebrafish models被引量：25收藏
- 作者：Lu, Jian Yang, Yun Zhu, Lianhua Li, Meng Xu, Wenping Zhang, Cheng Cheng, Jiagao Tao, Liming Li, Zhong Zhang, Yang
- 机构：East China Univ Sci & Technol;UT Southwestern Med Ctr
- 来源：CHEMOSPHERE 2022
- 关键词：Natural pyrethrins Hepatotoxicity Oxidative stress DNA damage Repair HepG2 cells Zebrafish
- Two New Antifungal Cyclic Lipopeptides from Bacillus marinus B-9987被引量：23收藏
- 作者：Zhang, Dao-Jing Liu, Rong-Feng Li, Yuan-Guang Tao, Li-Ming Tian, Li
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;State Ocean Adm
- 来源：CHEMICAL & PHARMACEUTICAL BULLETIN 2010
- 关键词：Bacillus marinus cyclic lipopeptide antifungal activity maribasin A maribasin B
- Bafilomycin K, a new antifungal macrolide from Streptomyces flavotricini Y12-26被引量：21收藏
- 作者：Zhang, Dao-jing Wei, Gang Wang, Ying Si, Cong-cong Tian, Li Tao, Li-ming Li, Yuan-guang
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;State Ocean Adm
- 来源：JOURNAL OF ANTIBIOTICS 2011
- 关键词：antifungal activity bafilomycin K macrolide Streptomyces flavotricini
