成果/Result
- Stem cell differentiation mediated by biomaterials/surfaces被引量：269收藏
- 作者：He, Hongyan Liu, Changsheng
- 机构： School of Material Science and Engineering
- 来源：Polymeric Biomaterials for Tissue Regeneration: From Surface/Interface Design to 3D Constructs 2016
- 关键词：Cell proliferation - Bone
- Therapeutic strategies against bacterial biofilms被引量：139收藏
- 作者：Bi, Yufang Xia, Guixue Shi, Chao Wan, Jianglin Liu, Longqiang Chen, Yuan Wu, Yueming Zhang, Wenjing Zhou, Min He, Hongyan Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：FUNDAMENTAL RESEARCH 2021
- 关键词：Antimicrobial resistance Biofilm Persister cell Nanomaterials Drug delivery
- Smart Biomaterials for Articular Cartilage Repair and Regeneration被引量：88收藏
- 作者：Gu, Zhanghao Wang, Jiayi Fu, Yu Pan, Hao He, Hongyan Gan, Qi Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Tongji Univ;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED FUNCTIONAL MATERIALS 2023
- 关键词：articular cartilage repair and regeneration smart biomaterials smart drug release smart scaffolds
- Nano-needle strontium-substituted apatite coating enhances osteoporotic osseointegration through promoting osteogenesis and inhibiting osteoclastogenesis被引量：76收藏
- 作者：Geng, Zhen Ji, Luli Li, Zhaoyang Wang, Jing He, Hongyan Cui, Zhenduo Yang, Xianjin Liu, Changsheng
- 机构：East China Univ Sci & Technol;Tianjin Univ;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOACTIVE MATERIALS 2021
- 关键词：Calcium Strontium Mineralization Osteoclast activity Osseointegration
- Laser transparent multiplexed SERS microneedles for in situ and real-time detection of inflammation被引量：48收藏
- 作者：Peng, Cheng Jin, Lili Wang, Feng Yang, Haifeng He, Hongyan
- 机构：Shanghai Normal Univ;East China Univ Sci & Technol
- 来源：BIOSENSORS & BIOELECTRONICS 2023
- 关键词：Inflammation Microneedles pH Reactive oxygen species level Redox potential Surface-enhanced Raman scattering
- The synergistic effect of strontium-substituted hydroxyapatite and microRNA-21 on improving bone remodeling and osseointegration被引量：47收藏
- 作者：Geng, Zhen Wang, Xiaogang Zhao, Jin Li, Zhaoyang Ma, Lili Zhu, Shengli Liang, Yanqin Cui, Zhenduo He, Hongyan Yang, Xianjin
- 机构：Tianjin Univ;East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2018
- 关键词：Physicochemical properties - Nanocapsules - Mineralogy - Composite coatings - Hydroxyapatite
- Strontium attenuates rhBMP-2-induced osteogenic differentiation via formation of Sr-rhBMP-2 complex and suppression of Smad-dependent signaling pathway被引量：37收藏
- 作者：Zhang, Wenjing Tian, Yu He, Hongyan Chen, Rui Ma, Yifan Guo, Han Yuan, Yuan Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Chinese Acad Sci
- 来源：ACTA BIOMATERIALIA 2016
- 关键词：Sr ions rhBMP-2 Sr-rhBMP-2 complex Bone formation
- Calcium ion-induced formation of β-sheet/-turn structure leading to alteration of osteogenic activity of bone morphogenetic protein-2被引量：33收藏
- 作者：Zhang, Wenjing He, Hongyan Tian, Yu Gan, Qi Zhang, Jing Yuan, Yuan Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：SCIENTIFIC REPORTS 2015
- A triple-coated ligament graft to facilitate ligament-bone healing by inhibiting fibrogenesis and promoting osteogenesis被引量：30收藏
- 作者：Li, Yamin Guo, Ximeng Dong, Shikui Zhu, Tonghe Chen, Yunsu Zhao, Song Xie, Guoming Jiang, Jia He, Hongyan Liu, Changsheng Zhao, Jinzhong
- 机构：Shanghai Jiao Tong Univ;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：ACTA BIOMATERIALIA 2020
- 关键词：Nano-coating Macrophage polarization Anti-fibrogenesis Osteogenesis Ligament-bone healing
- Chondroitin sulfate-polydopamine modified polyethylene terephthalate with extracellular matrix-mimetic immunoregulatory functions for osseointegration被引量：21收藏
- 作者：Li, Ya-Min Wu, Jing-Yao Jiang, Jia Dong, Shi-Kui Chen, Yun-Su He, Hong-Yan Liu, Chang-Sheng Zhao, Jin-Zhong
- 机构：Shanghai Jiaotong Univ Affiliated Peoples Hops 6;East China Univ Sci & Technol;Shanghai Jiaotong Univ Affiliated Peoples Hosp 6
- 来源：JOURNAL OF MATERIALS CHEMISTRY B 2019
- 关键词：Biomimetics - Plastic bottles - Grafting (chemical) - Stem cells - Sulfur compounds - Cytology - Bone
- The membrane-targeting mechanism of host defense peptides inspiring the design of polypeptide-conjugated gold nanoparticles exhibiting effective antibacterial activity against methicillin-resistant Staphylococcus aureus被引量：20收藏
- 作者：Zhang, Weiwei Wu, Yueming Liu, Longqiang Xiao, Ximian Cong, Zihao Shao, Ning Qiao, Zhongqian Chen, Kang Liu, Shiqi Zhang, Haodong Ji, Zhemin Shao, Xiaoyan Dai, Yidong He, Hongyan Xia, Jiang Fei, Jian Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Ruijin Rehabil Hosp;Chinese Univ Hong Kong;Shanghai Jiao Tong Univ
- 来源：JOURNAL OF MATERIALS CHEMISTRY B 2021
- 关键词：Ring opening polymerization - Synthesis (chemical) - Fiber optic sensors - Metal nanoparticles - Bacteria - Drug delivery
- Osteoinductive hybrid hydrogel membranes for in situ bone regeneration in hyperglycemia被引量：17收藏
- 作者：Liu, Yuanda Wang, Jing Jiang, Ming Li, Xueyan Zhang, Qinghao He, Hongyan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Eye & Ent Hosp Fudan Univ
- 来源：COLLOIDS AND SURFACES B-BIOINTERFACES 2022
- 关键词：Hyperglycemia Vascularization Bone regeneration Amorphous calcium phosphate Biomineralization
- Material-Mediated Immunotherapy to Regulate Bone Aging and Promote Bone Repair被引量：16收藏
- 作者：Xue, Pengfei Wang, Jiayi Fu, Yu He, Hongyan Gan, Qi Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Tongji Univ;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：SMALL 2025
- 关键词：biomaterials bone aging bone defects immunotherapy
- SERS-Based Microneedle Biosensor for In Situ and Sensitive Detection of Tyrosinase被引量：15收藏
- 作者：Gu, Zimeng Zhao, Di He, Hongyan Wang, Zhenhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOSENSORS-BASEL 2024
- 关键词：SERS tyrosinase microneedle in situ detection
- A Versatile Disorder-to-Order Technology to Upgrade Polymers into High-Performance Bioinspired Materials被引量：13收藏
- 作者：Liu, Shengyang He, Shicheng Chen, Can Li, Chunwang Luo, Wei Zheng, Kaikai Wang, Jing Li, Zhiyong He, Hongyan Chen, Qiang Li, Yulin
- 机构：East China Univ Sci & Technol;Southeast Univ;Shanghai Univ;Hubei Univ
- 来源：ADVANCED HEALTHCARE MATERIALS 2023
- 关键词：biodegradable polymers high strength self-reinforcement stereo-composites
- Simple, ultrasensitive detection of superoxide anion radical mutations in melanoma mice with SERS microneedles被引量：13收藏
- 作者：He, Miao Jin, Lili Wang, Feng Wang, Xin You, Yanli He, Hongyan
- 机构：East China Univ Sci & Technol;Shanghai Normal Univ;Second Mil Med Univ
- 来源：SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 2024
- 关键词：SERS O2 & sdot -detection Melanoma Microneedle
- Nano-needle strontium-substituted apatite coating enhances osteoporotic osseointegration through promoting osteogenesis and inhibiting osteoclastogenesis被引量：10收藏
- 作者：Zhen Geng Luli Ji Zhaoyang Li Jing Wang Hongyan He Zhenduo Cui Xianjin Yang Changsheng Liu
- 机构：Key Laboratory for Ultrafine Materials of Ministry of Education;Tianjin Key Laboratory of Composite and Functional Materials;Engineering Research Center for Biomedical Materials of the Ministry of Education;The State Key Laboratory of Bioreactor Engineering
- 来源：生物活性材料（英文） 2021
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- Wearable, antibacterial, and self-healable modular sensors for monitoring joints movement ultra-sensitively被引量：8收藏
- 作者：Sha, Dongyong Tang, Shuaimin Dong, Zeyu Chen, Kai Wang, Nan Liu, Changsheng Ling, Xiaofeng He, Hongyan Yuan, Yuan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：EUROPEAN POLYMER JOURNAL 2022
- 关键词：Multi-function hydrogel Modular design Flexible digital arthritis sensor system Remote real-time monitoring
- Robust hierarchical porous MBG scaffolds with promoted biomineralization ability被引量：8收藏
- 作者：Xie, Peng Du, Jiahui Li, Yulin Wu, Jingyao He, Hongyan Jiang, Xinquan Liu, Changsheng
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shanghai Res Inst Stomatol
- 来源：COLLOIDS AND SURFACES B-BIOINTERFACES 2019
- 关键词：Nanofiber-enhanced scaffolds Macro/micro/nano architecture Biomimetic interface Biomineralized acceleration Bone regeneration
- Therapeutic strategies against bacterial biofilms被引量：7收藏
- 作者：Yufang Bi Guixue Xia Chao Shi Jianglin Wan Longqiang Liu Yuan Chen Yueming Wu Wenjing Zhang Min Zhou Hongyan He Runhui Liu
- 机构：State Key Laboratory of Bioreactor Engineering;Frontiers Science Center for Materiobiology and Dynamic Chemistry
- 来源：自然科学基础研究（英文版） 2021
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- Fabrication of PLCL Block Polymer with Tunable Structure and Properties for Biomedical Application被引量：7收藏
- 作者：Luo, Chenmin Liu, Shengyang Luo, Wei Wang, Jing He, Hongyan Chen, Can Xiao, Lan Liu, Changsheng Li, Yulin
- 机构：East China Univ Sci & Technol;Shanghai Univ;Queensland Univ Technol QUT;Queensland Univ Technol QUT
- 来源：MACROMOLECULAR BIOSCIENCE 2023
- 关键词：biodegradable block copolymers definite compositions poly( L-lactide-b-epsilon-caprolactone) pre-polymerization
- Microneedle Assisted Melittin-Chondroitin Sulfate Administration for the Transdermal Therapy of Rheumatoid Arthritis被引量：6收藏
- 作者：Jin, Lili Wang, Zhenhui Peng, Cheng He, Miao Wang, Feng He, Hongyan Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Normal Univ
- 来源：ADVANCED HEALTHCARE MATERIALS 2025
- 关键词：chondroitin sulphate melittin microneedles rheumatoid arthritis surface-enhanced Raman scattering
- 钛基体表面多级孔洞结构的制备和生物活性研究被引量：5收藏
- 作者：朱洪强 何宏燕 袁媛 刘昌胜
- 机构：华东理工大学超细材料制备与应用教育部重点实验室
- 来源：《表面技术》 2015
- 关键词：钛基体 多级孔洞结构 碱热处理 羟基磷灰石 生物活性
- 摘要：目的通过调控钛基体表面的结构和特性，提高惰性钛基体表面的生物活性，改善其医用植入效果。方法采用碱热处理方法在钛基体表面构建多级孔洞结构，对改性后钛片的表面形貌、成分、结构、亲疏水性进行表征，评价钛片表面对类骨磷灰石的诱导...
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- 基于微流控技术的海藻酸钠微球可控制备与性能被引量：4收藏
- 作者：魏天翔 翟龙玉 金莉莉 何宏燕
- 机构：华东理工大学材料科学与工程学院
- 来源：《功能高分子学报》 2023
- 关键词：微流控技术 水凝胶 微球 海藻酸钠 生物相容性
- 摘要：对海藻酸钠(SA)进行氧化,并利用碳二亚胺法使其接枝细胞黏附肽,制得改性海藻酸钠(ROSA)。以ROSA为原料,采用微流控技术可控制备单分散性良好的水凝胶微球。利用倒置光学显微镜、激光共聚焦显微镜等对微球表面形貌及生物相...
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- Reverse milling-sputtering technology to develop scalable microneedle patches for analgesia被引量：3收藏
- 作者：Jin, Lili He, Miao Chen, Ying Liu, Changsheng He, Hongyan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：MATERIALS TODAY COMMUNICATIONS 2023
- 关键词：Microneedle patches Reverse milling -sputtering Analgesia
- 等离子体辅助纳米涂层的构建及其成骨性能被引量：3收藏
- 作者：郭西萌 金莉莉 李春旺 何宏燕 刘昌胜
- 机构：华东理工大学材料科学与工程学院
- 来源：《功能高分子学报》 2022
- 关键词：聚对苯二甲酸乙二酯 骨形态发生蛋白 成骨分化 生物相容性 骨间充质干细胞
- 摘要：通过氧等离子体处理,在聚对苯二甲酸乙二酯(PET)表面引入羟基,提高了其表面的亲水性。利用静电吸附等方式在PET材料表面先后载入表没食子儿茶素没食子酸酯(EGCG)、纤维黏连蛋白(Fn)和骨形态发生蛋白-2 (rhBMP...
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- Convenient and Controllable Synthesis of Poly(2-oxazoline)-Conjugated Doxorubicin for Regulating Anti-Tumor Selectivity被引量：2收藏
- 作者：Zhou, Min Cui, Ruxin Luo, Zhengjie Cong, Zihao Shao, Ning Yuan, Ling Gu, Jiawei He, Hongyan Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF FUNCTIONAL BIOMATERIALS 2023
- 关键词：poly(2-oxazoline) poly(2-oxazoline)-doxorubicin conjugation facile synthesis anti-tumor selectivity
- 透明质酸微阵列结构的构建及其生物相容性研究被引量：2收藏
- 作者：常铃雪 何宏燕 金莉莉 刘昌胜
- 机构：华东理工大学材料科学与工程学院
- 来源：《功能高分子学报》 2020
- 关键词：微阵列结构 透明质酸薄膜 生物相容性 骨间充质干细胞
- 摘要：植入材料表面的微结构在骨修复和组织再生中至关重要,而微阵列结构的可控制备是影响细胞尤其是骨间充质干细胞(BMSCs)生物学行为的关键因素之一。制备微阵列结构的材料通常降解性较差、生物活性不足。本文选用可降解高分子透明质酸...
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- Effective incorporation of rhBMP-2 on implantable titanium disks with microstructures by using electrostatic spraying deposition被引量：2收藏
- 作者：Qin, Jiankang He, Hongyan Zhang, Wenjing Chen, Fangping Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：RSC ADVANCES 2016
- 关键词：Bone - Scanning electron microscopy - Cell adhesion - Coatings - Atomic force microscopy - Proteins - Electrostatics - Bioactivity - Deposits - Molecular biology
- 种植表面骨诱导型涂层的制备及生物学特性研究被引量：1收藏
- 作者：何宏燕 李春旺
- 机构：华东理工大学材料科学与工程学院
- 来源：《浙江工业大学学报》 2022
- 关键词：牙种植体 壳聚糖 静电喷涂 rhBMP-2
- 摘要：为了增强喷砂酸蚀(SLA)牙植体的生物活性,促进其骨整合能力,对SLA牙种植体表面进行氧等离子体亲水处理,将重组人骨形态发生蛋白-2(rhBMP-2)溶于壳聚糖(CS)溶液后静电喷涂(ES)在其表面,利用扫描电子显微镜、...
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