袁媛 收藏
( 任职于 材料科学与工程学院)
主要经历与简历： 2005年6月获华东理工大学生物材料专业博士学位。2007年3月~2008年9月在美国The Ohio State University从事博士后研究。1998年毕业留校，2005年起任副教授，2012年晋升教授。2011年入选教育部新世纪优秀人才计划。 主要研究方向： （1）生物材料的活性化 （2）纳米生物材料 主要社会兼职： 中国生物材料协会会员，中国复合材料学会会员 主要学术成果 发表论文、专著、专利、获奖情况 （1）Gan Q, Lu XY, Dong WJ, Yua... 详细>>
被引量：8,805H指数：54SCI-EXPANDED： 193 EI： 175 北大核心： 33 CSSCI： 1 CSCD： 37
- Size-mediated cytotoxicity and apoptosis of hydroxyapatite nanoparticles in human hepatoma HepG2 cells被引量：221收藏
- 作者：Yuan, Yuan Liu, Changsheng Qjan, Jiangchao Wang, Jing Zhang, Yuan
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIOMATERIALS 2010
- 关键词：Hydroxyapatite nanoparticles Cytotoxicity Apoptosis-induction Human hepatoma HepG2 cells Size-mediated Mitochondrial-dependent pathway
- 质疑
- Bioinspired trimodal macro/micro/nano-porous scaffolds loading rhBMP-2 for complete regeneration of critical size bone defect被引量：207收藏
- 作者：Tang, Wei Lin, Dan Yu, Yuanman Niu, Haoyi Guo, Han Yuan, Yuan Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Chinese Acad Sci
- 来源：ACTA BIOMATERIALIA 2016
- 关键词：Trimodal macro/micro/nano-porous architecture Recombinant human bone morphogenetic protein-2 Critical size bone defect Mesoporous bioactive glass
- 质疑
- Long-circulating polymeric nanoparticles bearing a combinatorial coating of PEG and water-soluble chitosan被引量：191收藏
- 作者：Sheng, Yan Liu, Changsheng Yuan, Yuan Tao, Xinyi Yang, Fan Shan, Xiaoqian Zhou, Huanjun Xu, Feng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIOMATERIALS 2009
- 关键词：Polymeric nanoparticles Polyethylene glycol Water-soluble chitosan Long-circulating Biodistribution
- 质疑
- Magnesium modification of a calcium phosphate cement alters bone marrow stromal cell behavior via an integrin-mediated mechanism被引量：191收藏
- 作者：Zhang, Jing Ma, Xiaoyu Lin, Dan Shi, Hengsong Yuan, Yuan Tang, Wei Zhou, Huanjun Guo, Han Qian, Jiangchao Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIOMATERIALS 2015
- 关键词：Magnesium/calcium phosphate cements Cell adhesion Osteogenic differentiation Fibronectin Integrin
- 质疑
- Impact of Antifouling PEG Layer on the Performance of Functional Peptides in Regulating Cell Behaviors被引量：190收藏
- 作者：Chen, Qj Yu, Shan Zhang, Donghui Zhang, Wenjing Zhang, Haodong Zou, Jingcheng Mao, Zhengwei Yuan, Yuan Gao, Changyou Liu, Runhui
- 机构：East China Univ Sci & Technol;Zhejiang Univ
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2019
- 关键词：Peptides - Chain length - Adhesives - Cells - Scaffolds (biology) - Cell engineering
- 质疑
- Degradable, antibacterial silver exchanged mesoporous silica spheres for hemorrhage control被引量：182收藏
- 作者：Dai, Chenglong Yuan, Yuan Liu, Changsheng Wei, Jie Hong, Hua Li, Xiaosheng Pan, Xiaohua
- 机构：E China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：BIOMATERIALS 2009
- 关键词：Mesoporous silica sphere Hemostatic efficiency Degradation Antibacterial
- 质疑
- A magnetic, reversible pH-responsive nanogated ensemble based on Fe3O4 nanoparticles-capped mesoporous silica被引量：171收藏
- 作者：Gan, Qi Lu, Xunyu Yuan, Yuan Qian, Jiangchao Zhou, Huanjun Lu, Xun Shi, Jianlin Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIOMATERIALS 2011
- 关键词：pH-responsive Mesoporous silica Magnetic Gate-like Biocompatibility
- 质疑
- Injectable Double-Crosslinked Adhesive Hydrogels with High Mechanical Resilience and Effective Energy Dissipation for Joint Wound Treatment被引量：169收藏
- 作者：Chen, Kai Wu, Zihan Liu, Yutong Yuan, Yuan Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED FUNCTIONAL MATERIALS 2022
- 关键词：adhesive hydrogels dynamic environment energy dissipation joint wound treatment mechanical resilience
- 质疑
- N2-Polarized Neutrophils Guide Bone Mesenchymal Stem Cell Recruitment and Initiate Bone Regeneration: A Missing Piece of the Bone Regeneration Puzzle被引量：165收藏
- 作者：Cai, Bolei Lin, Dan Li, Yan Wang, Le Xie, Jirong Dai, Taiqiang Liu, Fuwei Tang, Mingyue Tian, Lei Yuan, Yuan Kong, Liang Shen, Steve G. F.
- 机构：Shanghai Jiao Tong Univ;Shanghai Res Inst Stomatol;Fourth Mil Med Univ;Fourth Mil Med Univ;Fourth Mil Med Univ
- 来源：ADVANCED SCIENCE 2021
- 关键词：bone regeneration interleukin-8 neutrophils stem cell recruitment stromal cell-derived factor-1 alpha
- 质疑
- Bioinspired, Injectable, Quaternized Hydroxyethyl Cellulose Composite Hydrogel Coordinated by Mesocellular Silica Foam for Rapid, Noncompressible Hemostasis and Wound Healing被引量：158收藏
- 作者：Wang, Chengwei Niu, Haoyi Ma, Xiaoyu Hong, Hua Yuan, Yuan Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Wego Biol Technol Co Ltd
- 来源：ACS APPLIED MATERIALS & INTERFACES 2019
- 关键词：hydroxyethyl cellulose mesocellular foam hemostasis antibacterial wound healing
- 质疑
- 溶胶-凝胶法制备纳米羟基磷灰石被引量：155收藏
- 作者：袁媛 刘昌胜
- 机构：华东理工大学生物材料研究所
- 来源：《中国医学科学院学报》 2002
- 关键词：纳米粉末 羟基磷灰石 溶胶-凝胶法
- 摘要：目的以四水硝酸钙和磷酸三甲酯为原料,水和无水乙醇为溶剂,采用溶胶-凝胶法合成纳米羟基磷灰石;并对影响溶胶-凝胶形成的工艺条件(溶剂的选择及加入量、溶液的pH值)以及干凝胶的低温燃烧特性进行研究。方法利用乌氏粘度计测定溶胶...
- 下载全文在线阅读质疑
- In vitro cytotoxicity and induction of apoptosis by silica nanoparticles in human HepG2 hepatoma cells被引量：138收藏
- 作者：Lu, Xun Qian, Jiangchao Zhou, Huanjun Gan, Qi Tang, Wei Lu, Jingxiong Yuan, Yuan Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF NANOMEDICINE 2011
- 关键词：silica nanoparticles cytotoxicity apoptosis HepG2 cells mitochondrial-dependent pathway oxidative stress
- 质疑
- Sulfated polysaccharide directs therapeutic angiogenesis via endogenous VEGF secretion of macrophages被引量：134收藏
- 作者：Yu, Yuanman Dai, Kai Gao, Zehua Tang, Wei Shen, Tong Yuan, Yuan Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：SCIENCE ADVANCES 2021
- 关键词：Diseases
- 质疑
- RhBMP-2-loaded calcium silicate/calcium phosphate cement scaffold with hierarchically porous structure for enhanced bone tissue regeneration被引量：133收藏
- 作者：Zhang, Jing Zhou, Huanjun Yang, Kai Yuan, Yuan Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIOMATERIALS 2013
- 关键词：Calcium silicate/calcium phosphate cement rhBMP-2 Bone regeneration Hierarchical porosity
- 质疑
- Rapid initiation of guided bone regeneration driven by spatiotemporal delivery of IL-8 and BMP-2 from hierarchical MBG-based scaffold被引量：126收藏
- 作者：Lin, Dan Chai, Yanjun Ma, Yifan Duan, Bing Yuan, Yuan Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS 2019
- 关键词：Rapid initiation BMP-2 IL-8 MBG In situ guided bone regeneration
- 质疑
- Tannic acid-loaded mesoporous silica for rapid hemostasis and antibacterial activity被引量：124收藏
- 作者：Wang, Chengwei Zhou, Huayi Niu, Haoyi Ma, Xiaoyu Yuan, Yuan Hong, Hua Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Wego Biol Technol Co Ltd
- 来源：BIOMATERIALS SCIENCE 2018
- 关键词：Flavonoids - Grafting (chemical) - Blood - Bacteria - Tannins
- 质疑
- Harnessing 4D Printing Bioscaffolds for Advanced Orthopedics被引量：124收藏
- 作者：Chen, Xi Han, Shuyan Wu, Weihui Wu, Zihan Yuan, Yuan Wu, Jun Liu, Changsheng
- 机构：East China Univ Sci & Technol;Sun Yat Sen Univ
- 来源：SMALL 2022
- 关键词：bioprinting bone regeneration scaffolds shape-memory materials tissue engineering
- 质疑
- A dual-delivery system of pH-responsive chitosan-functionalized mesoporous silica nanoparticles bearing BMP-2 and dexamethasone for enhanced bone regeneration被引量：122收藏
- 作者：Gan, Qi Zhu, Jiaoyang Yuan, Yuan Liu, Honglai Qian, Jiangchao Li, Yongsheng Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MATERIALS CHEMISTRY B 2015
- 关键词：Bone - Targeted drug delivery - Sol-gels - Sol-gel process - Silica nanoparticles - Mesoporous materials - Proteins - Controlled drug delivery
- 质疑
- Charge-Reversal APTES-Modified Mesoporous Silica Nanoparticles with High Drug Loading and Release Controllability被引量：121收藏
- 作者：Wang, Yifeng Sun, Yi Wang, Jine Yang, Yang Li, Yulin Yuan, Yuan Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2016
- 关键词：mesoporous silica nanocarriers charge reversal doxorubicin drug delivery pH responsive
- 质疑
- Nanotechnology platforms for cancer immunotherapy被引量：113收藏
- 作者：Yang, Zhaogang Ma, Yifan Zhao, Hai Yuan, Yuan Kim, Betty Y. S.
- 机构：Univ Texas Southwestern Med Ctr Dallas;Ohio State Univ;Univ Texas MD Anderson Canc Ctr;East China Univ Sci & Technol
- 来源：WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY 2020
- 关键词：cancer immunotherapy immunomodulatory agents nanoplatforms
- 质疑
- Mitochondria-Targeted Hydroxyapatite Nanoparticles for Selective Growth Inhibition of Lung Cancer in Vitro and in Vivo被引量：106收藏
- 作者：Sun, Yi Chen, Yaying Ma, Xiaoyu Yuan, Yuan Liu, Changsheng Kohn, Joachim Qian, Jiangchao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Rutgers State Univ
- 来源：ACS APPLIED MATERIALS & INTERFACES 2016
- 关键词：hydroxyapatite nanoparticles lung cancer mitochondrion-targeted cytotoxicity uptake
- 质疑
- Injectable Hydrogel with NIR Light-Responsive, Dual-Mode PTH Release for Osteoregeneration in Osteoporosis被引量：100收藏
- 作者：Kuang, Lijun Huang, Jinghuan Liu, Yutong Li, Xiaolin Yuan, Yuan Liu, Changsheng
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ Affiliated Peoples Hosp 6
- 来源：ADVANCED FUNCTIONAL MATERIALS 2021
- 关键词：dual-mode release injectable hydrogels near-infrared light osteoporotic bone repair parathyroid hormone pores formation
- 质疑
- Self-Assembled Injectable Nanocomposite Hydrogels Coordinated by in Situ Generated CaP Nanoparticles for Bone Regeneration被引量：96收藏
- 作者：Kuang, Lijun Ma, Xiaoyu Ma, Yifan Yao, Yuan Tariq, Muhammad Yuan, Yuan Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2019
- 关键词：in situ generated CaP nanoparticles injectable nanocomposite hydrogels self-assembly Apt-functionalized bone regeneration
- 质疑
- Rejuvenating Aged Bone Repair through Multihierarchy Reactive Oxygen Species-Regulated Hydrogel被引量：93收藏
- 作者：He, Zirui Sun, Chuanhao Ma, Yifan Chen, Xi Wang, Ying Chen, Kai Xie, Fangru Zhang, Yan Yuan, Yuan Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Ohio State Univ
- 来源：ADVANCED MATERIALS 2024
- 关键词：aged bone regeneration poly(diselenide-carbonate) nanomicelles ROS-scavenging hydrogel senescent microenvironment
- 质疑
- Amphiphilic Polymer-Mediated Formation of Laponite-Based Nanohybrids with Robust Stability and pH Sensitivity for Anticancer Drug Delivery被引量：93收藏
- 作者：Wang, Guoying Maciel, Dina Wu, Yilun Rodrigues, Joao Shi, Xiangyang Yuan, Yuan Liu, Changsheng Tomas, Helena Li, Yulin
- 机构：Univ Madeira;E China Univ Sci & Technol;E China Univ Sci & Technol;Donghua Univ
- 来源：ACS APPLIED MATERIALS & INTERFACES 2014
- 关键词：amphiphilic polymer Laponite doxorubicin pH sensitive anticancer
- 质疑
- Dual mechanism β-amino acid polymers promoting cell adhesion被引量：92收藏
- 作者：Chen, Qi Zhang, Donghui Zhang, Wenjing Zhang, Haodong Zou, Jingcheng Chen, Mingjiao Li, Jin Yuan, Yuan Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：NATURE COMMUNICATIONS 2021
- 质疑
- Preparation of hemoglobin-loaded nano-sized particles with porous structure as oxygen carriers被引量：89收藏
- 作者：Zhao, Jian Liu, Chang-Sheng Yuan, Yuan Tao, Xin-Yi Shan, Xiao-Qian Sheng, Yan Wu, Fan
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：BIOMATERIALS 2007
- 关键词：nanoparticles hemoglobin encapsulation efficiency pore-connecting efficiency oxygen-carrying capacity circulation time
- 质疑
- Multifunctional Carbon Dots for Biomedical Applications: Diagnosis, Therapy, and Theranostic被引量：86收藏
- 作者：Wang, Jiayi Fu, Yu Gu, Zhanghao Pan, Hao Zhou, Panyu Gan, Qi Yuan, Yuan Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Tongji Univ;Naval Med Univ;East China Univ Sci & Technol
- 来源：SMALL 2024
- 关键词：carbon dots diagnosis therapy theranostic
- 质疑
- Differential cytotoxicity and particle action of hydroxyapatite nanoparticles in human cancer cells被引量：86收藏
- 作者：Tang, Wei Yuan, Yuan Liu, Changsheng Wu, Yuequn Lu, Xun Qian, Jiangchao
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：NANOMEDICINE 2014
- 关键词：apoptosis induction cell type-dependent cytotoxicity cellular uptake and distribution hydroxyapatite nanoparticles intracellular calcium concentration reactive oxygen species
- 质疑
- A viscoelastic PEGylated poly(glycerol sebacate)-based bilayer scaffold for cartilage regeneration in full-thickness osteochondral defect被引量：86收藏
- 作者：Lin, Dan Cai, Bolei Wang, Le Cai, Lisha Wang, Zihao Xie, Jirong Lv, Qian-xin Yuan, Yuan Liu, Changsheng Shen, Steve G. F.
- 机构：Shanghai Jiao Tong Univ;Shanghai Res Inst Stomatol;East China Univ Sci & Technol;Fourth Mil Med Univ;Jiamusi Univ
- 来源：BIOMATERIALS 2020
- 关键词：Viscoelastic PEGylated poly(glycerol sebacate) Cartilage regeneration Osteochondral regeneration Full-thickness articular defects Bilayer scaffold
- 质疑
