刘润辉 收藏
( 任职于 材料科学与工程学院)
主要研究方向: 模拟天然蛋白功能的合成高分子生物材料，包括： 1. 功能化聚合物单体的合成；多功能高分子材料的制备及合成方法研究 2. 生物相容、生物可降解高分子材料的研究与开发 3. 抗细菌、抗真菌生物材料的研制与作用机理研究 4. 具有细胞黏附、细胞选择功能的生物材料研究及在组织修复中的应用 5. 抗非特异性蛋白吸附及微生物生物膜形成的防污材料研究及在生物医学工程领域的应用 6. 蛋白类及小分子药物的体内传输和可控释放研究 代表性学术论文: 15. Liu, R.; Chen, X.; Falk, S.; Masters, K. S.; Weisbl... 详细>>
- Dealing with the Foreign-Body Response to Implanted Biomaterials: Strategies and Applications of New Materials被引量：329收藏
- 作者：Zhang, Donghui Chen, Qi Shi, Chao Chen, Minzhang Ma, Kaiqian Wan, Jianglin Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED FUNCTIONAL MATERIALS 2021
- 关键词：anti‐ foreign‐ body response foreign‐ body response implants medical devices
- 质疑
- Addressing MRSA infection and antibacterial resistance with peptoid polymers被引量：236收藏
- 作者：Xie, Jiayang Zhou, Min Qian, Yuxin Cong, Zihao Chen, Sheng Zhang, Wenjing Jiang, Weinan Dai, Chengzhi Shao, Ning Ji, Zhemin Zou, Jingcheng Xiao, Ximian Liu, Longqiang Chen, Minzhang Li, Jin Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：NATURE COMMUNICATIONS 2021
- 质疑
- Poly(2-Oxazoline)-Based Functional Peptide Mimics: Eradicating MRSA Infections and Persisters while Alleviating Antimicrobial Resistance被引量：229收藏
- 作者：Zhou, Min Qian, Yuxin Xie, Jiayang Zhang, Wenjing Jiang, Weinan Xiao, Ximian Chen, Sheng Dai, Chengzhi Cong, Zihao Ji, Zhemin Shao, Ning Liu, Longqiang Wu, Yuequn Liu, Runhui
- 机构：East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：antibiotics antimicrobials drug design peptides polymers
- 质疑
- Host defense peptide-mimicking β-peptide polymer displaying strong antibacterial activity against cariogenic Streptococcus mutans被引量：224收藏
- 作者：Yang, Yi Qian, Yuxin Zhang, Mingxing Hao, Shuang Wang, Hui Fan, Yongqiang Liu, Runhui Xu, Dake Wang, Fuhui
- 机构：Northeastern Univ;Northeastern Univ;Northeastern Univ;East China Univ Sci & Technol;Liaoning Petrochem Univ
- 来源：JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 2023
- 关键词：beta-peptide polymers Host defense peptide S. mutans RT-qPCR Transcriptome
- 质疑
- Impact of Antifouling PEG Layer on the Performance of Functional Peptides in Regulating Cell Behaviors被引量：190收藏
- 作者：Chen, Qj Yu, Shan Zhang, Donghui Zhang, Wenjing Zhang, Haodong Zou, Jingcheng Mao, Zhengwei Yuan, Yuan Gao, Changyou Liu, Runhui
- 机构：East China Univ Sci & Technol;Zhejiang Univ
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2019
- 关键词：Peptides - Chain length - Adhesives - Cells - Scaffolds (biology) - Cell engineering
- 质疑
- Lithium hexamethyldisilazide initiated superfast ring opening polymerization of alpha-amino acid N-carboxyanhydrides被引量：163收藏
- 作者：Wu, Yueming Zhang, Danfeng Ma, Pengcheng Zhou, Ruiyi Hua, Lei Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：NATURE COMMUNICATIONS 2018
- 质疑
- Therapeutic strategies against bacterial biofilms被引量：139收藏
- 作者：Bi, Yufang Xia, Guixue Shi, Chao Wan, Jianglin Liu, Longqiang Chen, Yuan Wu, Yueming Zhang, Wenjing Zhou, Min He, Hongyan Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：FUNDAMENTAL RESEARCH 2021
- 关键词：Antimicrobial resistance Biofilm Persister cell Nanomaterials Drug delivery
- 质疑
- Secondary Amine Pendant β-Peptide Polymers Displaying Potent Antibacterial Activity and Promising Therapeutic Potential in Treating MRSA-Induced Wound Infections and Keratitis被引量：124收藏
- 作者：Qian, Yuxin Deng, Shuai Cong, Zihao Zhang, Haodong Lu, Ziyi Shao, Ning Bhatti, Sonia Abid Zhou, Cong Cheng, Jiagao Gellman, Samuel H. Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Wisconsin
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2022
- 关键词：Amines - Antibiotics - Cytotoxicity - Amino acids - Functional polymers
- 质疑
- Surface Modified with a Host Defense Peptide-Mimicking β-Peptide Polymer Kills Bacteria on Contact with High Efficacy被引量：118收藏
- 作者：Qian, Yuxin Qi, Fan Chen, Qi Zhang, Qiang Qiao, Zhongqian Zhang, Si Wei, Ting Yu, Qian Yu, Shan Mao, Zhengwei Gao, Changyou Ding, Yiru Cheng, Yanyong Jin, Chenyu Xie, Hexin Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2018
- 关键词：beta-peptide polymer graft to antimicrobial surface divalent ion membrane destabilization biocompatible surface antimicrobial resistance MRSA
- 质疑
- Switching from membrane disrupting to membrane crossing, an effective strategy in designing antibacterial polypeptide被引量：110收藏
- 作者：Zhang, Haodong Chen, Qi Xie, Jiayang Cong, Zihao Cao, Chuntao Zhang, Wenjing Zhang, Donghui Chen, Sheng Gu, Jiawei Deng, Shuai Qiao, Zhongqian Zhang, Xinyue Li, Maoquan Lu, Ziyi Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Tongji Univ
- 来源：SCIENCE ADVANCES 2023
- 关键词：Amino acids - Antimicrobial agents - Bacteria - Health risks - Membranes - Polypeptides
- 质疑
- Bio-inspired poly-DL-serine materials resist the foreign-body response被引量：101收藏
- 作者：Zhang, Donghui Chen, Qi Bi, Yufang Zhang, Haodong Chen, Minzhang Wan, Jianglin Shi, Chao Zhang, Wenjing Zhang, Junyu Qiao, Zhongqian Li, Jin Chen, Shengfu Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Zhejiang Univ
- 来源：NATURE COMMUNICATIONS 2021
- 质疑
- Host defense peptide mimicking poly--peptides with fast, potent and broad spectrum antibacterial activities被引量：94收藏
- 作者：Zhang, Qiang Ma, Pengcheng Xie, Jiayang Zhang, Si Xiao, Ximian Qiao, Zhongqian Shao, Ning Zhou, Min Zhang, Wenjing Dai, Chengzhi Qian, Yuxin Qi, Fan Liu, Runhui
- 机构：East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2019
- 关键词：Antibiotics - Bacteria - Mammals - Antimicrobial agents - Network security
- 质疑
- Manganese dioxide nanozyme for reactive oxygen therapy of bacterial infection and wound healing被引量：94收藏
- 作者：Liu, Li Wang, Cheng Li, Yuting Qiu, Lin Zhou, Shuwen Cui, Pengfei Jiang, Pengju Ni, Xinye Liu, Runhui Du, Xuancheng Wang, Jianhao Xia, Jiang
- 机构：Changzhou Univ;Nanjing Med Univ;East China Univ Sci & Technol;Shandong Univ;Chinese Univ Hong Kong
- 来源：BIOMATERIALS SCIENCE 2021
- 关键词：Mammals - Oxygen - Escherichia coli - Manganese oxide - Tissue regeneration - Biocompatibility
- 质疑
- Dual mechanism β-amino acid polymers promoting cell adhesion被引量：92收藏
- 作者：Chen, Qi Zhang, Donghui Zhang, Wenjing Zhang, Haodong Zou, Jingcheng Chen, Mingjiao Li, Jin Yuan, Yuan Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：NATURE COMMUNICATIONS 2021
- 质疑
- Short Guanidinium-Functionalized Poly(2-oxazoline)s Displaying Potent Therapeutic Efficacy on Drug-Resistant Fungal Infections被引量：84收藏
- 作者：Jiang, Weinan Zhou, Min Cong, Zihao Xie, Jiayang Zhang, Wenjing Chen, Sheng Zou, Jingcheng Ji, Zhemin Shao, Ning Chen, Xin Li, Maoquan Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Tongji Univ
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2022
- 关键词：Antifungal Polymers Drug-Resistant Fungi Guanidinium-Pendent Peptidomimetics Poly(2-oxazoline)s
- 质疑
- Practical Preparation of Infection-Resistant Biomedical Surfaces from Antimicrobial β-Peptide Polymers被引量：83收藏
- 作者：Qi, Fan Qian, Yuxin Shao, Ning Zhou, Ruiyi Zhang, Si Lu, Ziyi Zhou, Min Xie, Jiayang Wei, Ting Yu, Qian Liu, Runhui
- 机构：East China Univ Sci & Technol;Soochow Univ
- 来源：ACS APPLIED MATERIALS & INTERFACES 2019
- 关键词：beta-peptide polymer host defense peptide antimicrobial surface MRSA subcutaneous infection
- 质疑
- Silk-Inspired β-Peptide Materials Resist Fouling and the Foreign-Body Response被引量：82收藏
- 作者：Zhang, Donghui Chen, Qi Zhang, Wenjing Liu, Hengjiang Wan, Jianglin Qian, Yuxin Li, Bing Tang, Songchao Liu, Yu Chen, Shengfu Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Zhejiang Univ
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：materials science peptides polymers self-assembly surface chemistry
- 质疑
- Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications被引量：79收藏
- 作者：Wu, Yueming Chen, Kang Wang, Jiangzhou Chen, Minzhang Chen, Yuan She, Yunrui Yan, Zi Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：PROGRESS IN POLYMER SCIENCE 2023
- 关键词：Host defense peptides Antimicrobial amino acid polymers Antibiotic -resistant Polymerization methodology Antimicrobial drug candidates
- 质疑
- Advances in the antimicrobial treatment of osteomyelitis被引量：74收藏
- 作者：Zhong, Chao Wu, Yueming Lin, Haodong Liu, Runhui
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shanghai Gen Hosp;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：COMPOSITES PART B-ENGINEERING 2023
- 关键词：Osteomyelitis Antimicrobial agent therapy Physical therapy Immunotherapy
- 质疑
- Superfast and Water-Insensitive Polymerization on α-Amino Acid N-Carboxyanhydrides to Prepare Polypeptides Using Tetraalkylammonium Carboxylate as the Initiator被引量：73收藏
- 作者：Wu, Yueming Chen, Kang Wu, Xue Liu, Longqiang Zhang, Weiwei Ding, Yun Liu, Shiqi Zhou, Min Shao, Ning Ji, Zhemin Chen, Jiacheng Zhu, Minghui Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2021
- 关键词：antimicrobial aqueous polymerization in situ self-assembly NCA polymerization tetraalkylammonium carboxylate
- 质疑
- Recent Advances and Future Developments in the Preparation of Polypeptides via N-Carboxyanhydride (NCA) Ring-Opening Polymerization被引量：68收藏
- 作者：Wu, Yueming Chen, Kang Wang, Jiangzhou Chen, Minzhang Dai, Wenhui Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2024
- 质疑
- Peptide Polymer-Doped Cement Acting as an Effective Treatment of MRSA-Infected Chronic Osteomyelitis被引量：68收藏
- 作者：Wu, Yueming Lin, Yaofa Cong, Zihao Chen, Kang Xiao, Ximian Wu, Xue Liu, Longqiang She, Yunrui Liu, Shiqi Zhou, Ruiyi Yin, Gang Shao, Xiaoyan Dai, Yidong Lin, Haodong Liu, Runhui
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shanghai Gen Hosp;East China Univ Sci & Technol;Shanghai Ruijin Rehabil Hosp
- 来源：ADVANCED FUNCTIONAL MATERIALS 2022
- 关键词：antibacterial chronic osteomyelitis host defense peptides MRSA peptide polymers
- 质疑
- Heterochiral β-Peptide Polymers Combating Multidrug-Resistant Cancers Effectively without Inducing Drug Resistance被引量：67收藏
- 作者：Shao, Ning Yuan, Ling Ma, Pengcheng Zhou, Min Xiao, Ximian Cong, Zihao Wu, Yueming Xiao, Guohui Fei, Jian Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2022
- 关键词：Diseases - Biocompatibility - Cancer cells - Tumors
- 质疑
- Water-Insensitive Synthesis of Poly-β-Peptides with Defined Architecture被引量：66收藏
- 作者：Zhou, Min Xiao, Ximian Cong, Zihao Wu, Yueming Zhang, Wenjing Ma, Pengcheng Chen, Sheng Zhang, Haodong Zhang, Danfeng Zhang, Donghui Luan, Xiangfeng Mai, Yiyong Liu, Runhui
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：polymerization poly-beta-peptides secondary structure water-insensitive polymerization beta-NTA
- 质疑
- A dual-targeting antifungal is effective against multidrug-resistant human fungal pathogens被引量：61收藏
- 作者：Zhou, Min Liu, Longqiang Cong, Zihao Jiang, Weinan Xiao, Ximian Xie, Jiayang Luo, Zhengjie Chen, Sheng Wu, Yueming Xue, Xinying Shao, Ning Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Capital Med Univ;Shandong Second Med Univ
- 来源：NATURE MICROBIOLOGY 2024
- 质疑
- The impact of antifouling layers in fabricating bioactive surfaces被引量：61收藏
- 作者：Chen, Qi Zhang, Donghui Gu, Jiawei Zhang, Haodong Wu, Xue Cao, Chuntao Zhang, Xinyue Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACTA BIOMATERIALIA 2021
- 关键词：Fouling Antifouling PEG Bioactive surface Cell adhesion Functional peptides
- 质疑
- Effective and biocompatible antibacterial surfaces via facile synthesis and surface modification of peptide polymers被引量：61收藏
- 作者：Lu, Ziyi Wu, Yueming Cong, Zihao Qian, Yuxin Wu, Xue Shao, Ning Qiao, Zhongqian Zhang, Haodong She, Yunrui Chen, Kang Xiang, Hengxue Sun, Bin Yu, Qian Yuan, Yuan Lin, Haodong Zhu, Meifang Liu, Runhui
- 机构：East China Univ Sci & Technol;Donghua Univ;Soochow Univ;Shanghai Jiao Tong Univ;East China Univ Sci & Technol
- 来源：BIOACTIVE MATERIALS 2021
- 关键词：Peptide polymer Host defense peptide Antimicrobial surface MRSA Subcutaneous infection
- 质疑
- Single-Center Trifunctional Organocatalyst Enables Fast and Controlled Polymerization on N-Carboxyanhydride被引量：53收藏
- 作者：Chen, Kang Wu, Yueming Chen, Minzhang Wang, Jiangzhou Zhou, Min Chen, Xin Liu, Runhui
- 机构： State Key Laboratory of Bioreactor Engineering; Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism; Department of Biomaterials and Stem Cells; Key Laboratory for Ultrafine Materials
- 来源：ACS Central Science 2025
- 关键词：Carboxylation - Cationic polymerization - Organocatalyst - Reaction intermediates - Reaction rates - Ring opening polymerization
- 质疑
- Antimicrobial Properties and Application of Polysaccharides and Their Derivatives被引量：51收藏
- 作者：Xia, Gui-Xue Wu, Yue-Ming Bi, Yu-Fang Chen, Kang Zhang, Wei-Wei Liu, Shi-Qi Zhang, Wen-Jing Liu, Run-Hui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHINESE JOURNAL OF POLYMER SCIENCE 2021
- 关键词：Antimicrobial Drug resistance Polysaccharides Polysaccharide derivatives Chitosan
- 质疑
- Quaternized Polysaccharide-Based Cationic Micelles as a Macromolecular Approach to Eradicate Multidrug-Resistant Bacterial Infections while Mitigating Antimicrobial Resistance被引量：51收藏
- 作者：Xie, Fang Jiang, Lai Xiao, Ximian Lu, Yiwen Liu, Runhui Jiang, Wei Cai, Jie
- 机构：Wuhan Univ;Wuhan Univ;East China Univ Sci & Technol;Wuhan Univ
- 来源：SMALL 2022
- 关键词：multidrug-resistant infection polysaccharides quaternization wound healing
- 质疑
