成果/Result
- Production of Succinate from Acetate by Metabolically Engineered Escherichia coli被引量：90收藏
- 作者：Li, Yunjie Huang, Bing Wu, Hui Li, Zhimin Ye, Qin Zhang, Y-H Percival
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Virginia Tech;Chinese Acad Sci
- 来源：ACS SYNTHETIC BIOLOGY 2016
- 关键词：acetate succinate metabolic engineering Escherichia coli malic enzyme citrate synthase
- Improved succinic acid production in the anaerobic culture of an Escherichia coli PflB ldhA double mutant as a result of enhanced anaplerotic activities in the preceding aerobic culture被引量：89收藏
- 作者：Wu, Hui Li, Zhi-Min Zhou, Li Ye, Qin
- 机构：E China Univ Chem Technol
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2007
- Systematic manipulation of glutathione metabolism in Escherichia coli for improved glutathione production被引量：85收藏
- 作者：Zhang, Jing Quan, Cong Wang, Cheng Wu, Hui Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：MICROBIAL CELL FACTORIES 2016
- 关键词：Escherichia coli Glutathione Systematic manipulation Bifunctional glutathione synthetase Fed-batch fermentation
- Modular Engineering Intracellular NADH Regeneration Boosts Extracellular Electron Transfer of Shewanella oneidensis MR-1被引量：84收藏
- 作者：Li, Feng Li, Yuanxiu Sun, Liming Chen, Xiaoli An, Xingjuan Yin, Changji Cao, Yingxiu Wu, Hui Song, Hao
- 机构：Tianjin Univ;PetroChina Co Ltd;East China Univ Sci & Technol
- 来源：ACS SYNTHETIC BIOLOGY 2018
- 关键词：Shewanella oneidensis extracellular electron transfer NADH regeneration reducing equivalents cofactor engineering microbial fuel cells
- Central pathway engineering for enhanced succinate biosynthesis from acetate in Escherichia coli被引量：62收藏
- 作者：Huang, Bing Yang, Hao Fang, Guochen Zhang, Xing Wu, Hui Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2018
- 关键词：acetate cofactor engineering Escherichia coli metabolic engineering succinate
- Enhanced succinate production from glycerol by engineered Escherichia coli strains被引量：47收藏
- 作者：Li, Qing Wu, Hui Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCE TECHNOLOGY 2016
- 关键词：Succinate Escherichia coli Glycerol Phosphoenolpyruvate carboxykinase Two-stage fermentation
- Efficient isopropanol biosynthesis by engineered Escherichia coli using biologically produced acetate from syngas fermentation被引量：45收藏
- 作者：Yang, Hao Zhang, Can Lai, Ningyu Huang, Bing Fei, Peng Ding, Dawei Hu, Peng Gu, Yang Wu, Hui
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Shanghai GTL Biotech Co Ltd;China Natl Light Ind Council;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCE TECHNOLOGY 2020
- 关键词：Acetate Isopropanol Metabolic engineering Cofactor engineering Escherichia coli
- Advances in microbial production of medium-chain dicarboxylic acids for nylon materials被引量：45收藏
- 作者：Li, Guohui Huang, Dixuan Sui, Xue Li, Shiyun Huang, Bing Zhang, Xiaojuan Wu, Hui Deng, Yu
- 机构：Jiangnan Univ;East China Univ Sci & Technol;Jiangnan Univ;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council
- 来源：REACTION CHEMISTRY & ENGINEERING 2020
- 关键词：Indicators (chemical) - Textile industry - Liquid crystals - Biochemistry - Polyamides - Synthetic biology - Chemical contamination - Plants (botany) - Rayon - Metabolic engineering
- Enhanced production of 3-hydroxypropionic acid from glucose via malonyl-CoA pathway by engineered Escherichia coli被引量：45收藏
- 作者：Cheng, Zhuan Jiang, Jiaqi Wu, Hui Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCE TECHNOLOGY 2016
- 关键词：3-Hydroxypropionate Acetyl-CoA carboxylase Malonyl-CoA reductase Corynebacterium glutamicum Escherichia coli
- L-Cysteine Production in Escherichia coli Based on Rational Metabolic Engineering and Modular Strategy被引量：43收藏
- 作者：Liu, Han Fang, Guochen Wu, Hui Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council
- 来源：BIOTECHNOLOGY JOURNAL 2018
- 关键词：Escherichia coli L-cysteine modular strategy rational metabolic engineering
- One-pot synthesis of glutathione by a two-enzyme cascade using a thermophilic ATP regeneration system被引量：43收藏
- 作者：Zhang, Xing Wu, Hui Huang, Bing Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2017
- 关键词：Glutathione Bifunctional glutathione synthetase ATP regeneration Polyphosphate Polyphosphate kinase
- Search for live attenuated vaccine candidate against edwardsiellosis by mutating virulence-related genes of fish pathogen Edwardsiella tarda被引量：41收藏
- 作者：Xiao, J. Chen, T. Wang, Q. Liu, Q. Wang, X. Lv, Y. Wu, H. Zhang, Y.
- 机构：E China Univ Sci & Technol
- 来源：LETTERS IN APPLIED MICROBIOLOGY 2011
- 关键词：Edwardsiella tarda live attenuated vaccine virulence zebra fish
- Effect of NADPH availability on free fatty acid production in Escherichia coli被引量：41收藏
- 作者：Li, Wei Wu, Hui Li, Mai San, Ka-Yiu
- 机构：Rice Univ;East China Univ Sci & Technol;Rice Univ
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2018
- 关键词：E-coli Fatty acid production NADPH NAD(P)(+) transhydrogenase NAD(+) kinase
- Enhancing cordycepin production in liquid static cultivation of Cordyceps militaris by adding vegetable oils as the secondary carbon source被引量：39收藏
- 作者：Tang, Jiapeng Qian, Zhenqing Wu, Hui
- 机构：Nantong Univ;East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council
- 来源：BIORESOURCE TECHNOLOGY 2018
- 关键词：Cordyceps militaris Cordycepin production Peanut oil Liquid static cultivation Carbon metabolism
- Transcription Factor Engineering for High-Throughput Strain Evolution and Organic Acid Bioproduction: A Review被引量：37收藏
- 作者：Li, Jia-Wei Zhang, Xiao-Yan Wu, Hui Bai, Yun-Peng
- 机构：East China Univ Sci & Technol
- 来源：FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 2020
- 关键词：transcription factor biosensor metabolic engineering synthetic biology organic acid high-throughput screening
- Metabolic engineering of Escherichia coli carrying the hybrid acetone-biosynthesis pathway for efficient acetone biosynthesis from acetate被引量：32收藏
- 作者：Yang, Hao Huang, Bing Lai, Ningyu Gu, Yang Li, Zhimin Ye, Qin Wu, Hui
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council;Chinese Acad Sci
- 来源：MICROBIAL CELL FACTORIES 2019
- 关键词：Acetate Acetone Metabolic engineering Escherichia coli Gas-stripping Resting cell
- Production of succinate from simply purified crude glycerol by engineered Escherichia coli using two-stage fermentation被引量：31收藏
- 作者：Li, Qing Huang, Bing He, Qiaofei Lu, Jingxian Li, Xun Li, Zhimin Wu, Hui Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council;Nanjing Forestry Univ
- 来源：BIORESOURCES AND BIOPROCESSING 2018
- 关键词：Escherichia coli Succinate Crude glycerol Activated carbon Two-stage fermentation
- Ionic liquid form of donepezil: Preparation, characterization and formulation development被引量：31收藏
- 作者：Wu, Hao Fang, Fang Zheng, Lulu Ji, Weijie Qi, Minghui Hong, Minghuang Ren, Guobin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR LIQUIDS 2020
- 关键词：Ionic liquids Alzheimer's disease Donepezil Drug-in-adhesive patch Skin permeability
- One stone two birds: Biosynthesis of 3-hydroxypropionic acid from CO2 and syngas-derived acetic acid in Escherichia coli被引量：29收藏
- 作者：Lai, Ningyu Luo, Yuanchan Fei, Peng Hu, Peng Wu, Hui
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council;Shanghai GTL Biotech Co Ltd
- 来源：SYNTHETIC AND SYSTEMS BIOTECHNOLOGY 2021
- 关键词：Syngas-derived acetic acid 3-Hydroxypropionic acid Metabolic engineering Escherichia coli Dynamic regulation
- Succinic acid production and CO2 fixation using a metabolically engineered Escherichia coli in a bioreactor equipped with a self-inducing agitator被引量：28收藏
- 作者：Wu, Hui Li, Qing Li, Zhi-min Ye, Qin
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2012
- 关键词：Escherichia coli Succinic acid CO2 fixation Self-induction agitator Bioreactor
- Complete sequence of virulence plasmid pEIB1 from the marine fish pathogen Vibrio anguillarum strain MVM425 and location of its replication region被引量：28收藏
- 作者：Wu, H Ma, Y Zhang, Y Zhang, H
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF APPLIED MICROBIOLOGY 2004
- 关键词：genetic organization pEIB1 plasmid replication region Vibrio anguillarum
- Transgenic eukaryotic microalgae as green factories: providing new ideas for the production of biologically active substances被引量：27收藏
- 作者：Shi, Qianwen Chen, Cheng Zhang, Wei Wu, Ping Sun, Meng Wu, Hui Wu, Haizhen Fu, Pengcheng Fan, Jianhua
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Hainan Univ
- 来源：JOURNAL OF APPLIED PHYCOLOGY 2021
- 关键词：Eukaryotic microalgae Genetic engineering Metabolism Biopharmaceuticals production Therapeutic proteins
- Glutathione production by recombinant Escherichia coli expressing bifunctional glutathione synthetase被引量：27收藏
- 作者：Wang, Dezheng Wang, Cheng Wu, Hui Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2016
- 关键词：Glutathione Escherichia coli Bifunctional glutathione synthetase One-strain system Energy regeneration
- Heterologous gshF gene expression in various vector systems in Escherichia coli for enhanced glutathione production被引量：25收藏
- 作者：Wang, Cheng Zhang, Jing Wu, Hui Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2015
- 关键词：Antioxidant Glutathione Escherichia coil Bifunctional glutathione synthetase Fed-batch fermentation
- A novel regulatory pathway consisting of a two-component system and an ABC-type transporter contributes to butanol tolerance in Clostridium acetobutylicum被引量：24收藏
- 作者：Yang, Yunpeng Lang, Nannan Zhang, Lu Wu, Hui Jiang, Weihong Gu, Yang
- 机构：Chinese Acad Sci;East China Univ Sci & Technol
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2020
- 关键词：Two-component system Transporter Butanol tolerance Clostridia
- Secreted glyceraldehyde-3-phosphate dehydrogenase as a broad spectrum vaccine candidate against microbial infection in aquaculture被引量：24收藏
- 作者：Li, X. Wu, H. Zhang, M. Liang, S. Xiao, J. Wang, Q. Liu, Q. Zhang, Y.
- 机构：E China Univ Sci & Technol
- 来源：LETTERS IN APPLIED MICROBIOLOGY 2012
- 关键词：aquaculture cross-immunity GAPDH localization pathogenic bacteria
- Metabolic transistor strategy for controlling electron transfer chain activity in Escherichia coli被引量：22收藏
- 作者：Wu, Hui Tuli, Leepika Bennett, George N. San, Ka-Yiu
- 机构：Rice Univ;E China Univ Sci & Technol;Rice Univ
- 来源：METABOLIC ENGINEERING 2015
- 关键词：Escherichia coli Metabolic transistor Electron transfer chain Quinone Lactate Oxygen
- Efficient poly(3-hydroxybutyrate-co-lactate) production from corn stover hydrolysate by metabolically engineered Escherichia coli被引量：21收藏
- 作者：Wu, Ju Wei, Xiangju Guo, Pengye He, Aiyong Xu, Jiaxing Jin, Mingjie Zhang, Yanjun Wu, Hui
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Zhejiang Normal Univ;Huaiyin Normal Univ;Nanjing Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2021
- 关键词：Poly(3-hydroxybutyrate-co-lactate) E coli Promoter of ldhA Corn stover hydrolysate Lactate fraction
- Biosynthesis of (R)-3-hydroxybutyric acid from syngas-derived acetate in engineered Escherichia coli被引量：20收藏
- 作者：Fei, Peng Luo, Yuanchan Lai, Ningyu Wu, Hui
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council
- 来源：BIORESOURCE TECHNOLOGY 2021
- 关键词：Syngas-derived acetate (R)-3-hydroxybutyric acid propionyl-CoA transferase Clostridium beijerinckii Escherichia coli
- Enhancing the solubility of natural compound xanthotoxin by modulating stability via cocrystallization engineering被引量：19收藏
- 作者：Chen, Jin-Yao Wu, Hao Guo, Chun-Yang Zhu, Bin Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Dali Univ
- 来源：INTERNATIONAL JOURNAL OF PHARMACEUTICS 2019
- 关键词：Xanthotoxin Cocrystals Crystal structure Solubility Stability
