成果/Result
- Dealing with the ForEIgn-Body Response to Implanted Biomaterials: Strategies and Applications of New Materials被引量：329收藏
- 作者：Zhang, Donghui Chen, Qi Shi, Chao Chen, Minzhang Ma, Kaiqian Wan, Jianglin Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED FUNCTIONAL MATERIALS 2021
- 关键词：anti‐ forEIgn‐ body response forEIgn‐ body response implants medical devices
- Poly(2-Oxazoline)-Based Functional Peptide Mimics: Eradicating MRSA Infections and Persisters while Alleviating Antimicrobial Resistance被引量：229收藏
- 作者：Zhou, Min Qian, Yuxin Xie, Jiayang Zhang, Wenjing Jiang, Weinan Xiao, Ximian Chen, Sheng Dai, Chengzhi Cong, Zihao Ji, Zhemin Shao, Ning Liu, Longqiang Wu, Yuequn Liu, Runhui
- 机构：East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：antibiotics antimicrobials drug design peptides polymers
- Host defense peptide-mimicking β-peptide polymer displaying strong antibacterial activity against cariogenic Streptococcus mutans被引量：224收藏
- 作者：Yang, Yi Qian, Yuxin Zhang, Mingxing Hao, Shuang Wang, Hui Fan, Yongqiang Liu, Runhui Xu, Dake Wang, Fuhui
- 机构：Northeastern Univ;Northeastern Univ;Northeastern Univ;East China Univ Sci & Technol;Liaoning Petrochem Univ
- 来源：JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 2023
- 关键词：beta-peptide polymers Host defense peptide S. mutans RT-qPCR Transcriptome
- Impact of Antifouling PEG Layer on the Performance of Functional Peptides in Regulating Cell Behaviors被引量：190收藏
- 作者：Chen, Qj Yu, Shan Zhang, Donghui Zhang, Wenjing Zhang, Haodong Zou, Jingcheng Mao, Zhengwei Yuan, Yuan Gao, Changyou Liu, Runhui
- 机构：East China Univ Sci & Technol;Zhejiang Univ
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2019
- 关键词：Peptides - Chain length - Adhesives - Cells - Scaffolds (biology) - Cell engineering
- Secondary Amine Pendant β-Peptide Polymers Displaying Potent Antibacterial Activity and Promising Therapeutic Potential in Treating MRSA-Induced Wound Infections and Keratitis被引量：124收藏
- 作者：Qian, Yuxin Deng, Shuai Cong, Zihao Zhang, Haodong Lu, Ziyi Shao, Ning Bhatti, Sonia Abid Zhou, Cong Cheng, Jiagao Gellman, Samuel H. Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Wisconsin
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2022
- 关键词：Amines - Antibiotics - Cytotoxicity - Amino acids - Functional polymers
- Surface Modified with a Host Defense Peptide-Mimicking β-Peptide Polymer Kills Bacteria on Contact with High Efficacy被引量：118收藏
- 作者：Qian, Yuxin Qi, Fan Chen, Qi Zhang, Qiang Qiao, Zhongqian Zhang, Si Wei, Ting Yu, Qian Yu, Shan Mao, Zhengwei Gao, Changyou Ding, Yiru Cheng, Yanyong Jin, Chenyu Xie, Hexin Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2018
- 关键词：beta-peptide polymer graft to antimicrobial surface divalent ion membrane destabilization biocompatible surface antimicrobial resistance MRSA
- Switching from membrane disrupting to membrane crossing, an effective strategy in designing antibacterial polypeptide被引量：110收藏
- 作者：Zhang, Haodong Chen, Qi Xie, Jiayang Cong, Zihao Cao, Chuntao Zhang, Wenjing Zhang, Donghui Chen, Sheng Gu, Jiawei Deng, Shuai Qiao, Zhongqian Zhang, Xinyue Li, Maoquan Lu, Ziyi Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Tongji Univ
- 来源：SCIENCE ADVANCES 2023
- 关键词：Amino acids - Antimicrobial agents - Bacteria - Health risks - Membranes - Polypeptides
- Host defense peptide mimicking poly--peptides with fast, potent and broad spectrum antibacterial activities被引量：94收藏
- 作者：Zhang, Qiang Ma, Pengcheng Xie, Jiayang Zhang, Si Xiao, Ximian Qiao, Zhongqian Shao, Ning Zhou, Min Zhang, Wenjing Dai, Chengzhi Qian, Yuxin Qi, Fan Liu, Runhui
- 机构：East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2019
- 关键词：Antibiotics - Bacteria - Mammals - Antimicrobial agents - Network security
- Manganese dioxide nanozyme for reactive oxygen therapy of bacterial infection and wound healing被引量：94收藏
- 作者：Liu, Li Wang, Cheng Li, Yuting Qiu, Lin Zhou, Shuwen Cui, Pengfei Jiang, Pengju Ni, Xinye Liu, Runhui Du, Xuancheng Wang, Jianhao Xia, Jiang
- 机构：Changzhou Univ;Nanjing Med Univ;East China Univ Sci & Technol;Shandong Univ;Chinese Univ Hong Kong
- 来源：BIOMATERIALS SCIENCE 2021
- 关键词：Mammals - Oxygen - Escherichia coli - Manganese oxide - Tissue regeneration - Biocompatibility
- Short Guanidinium-Functionalized Poly(2-oxazoline)s Displaying Potent Therapeutic Efficacy on Drug-Resistant Fungal Infections被引量：84收藏
- 作者：Jiang, Weinan Zhou, Min Cong, Zihao Xie, Jiayang Zhang, Wenjing Chen, Sheng Zou, Jingcheng Ji, Zhemin Shao, Ning Chen, Xin Li, Maoquan Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Tongji Univ
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2022
- 关键词：Antifungal Polymers Drug-Resistant Fungi Guanidinium-Pendent Peptidomimetics Poly(2-oxazoline)s
- Practical Preparation of Infection-Resistant Biomedical Surfaces from Antimicrobial β-Peptide Polymers被引量：83收藏
- 作者：Qi, Fan Qian, Yuxin Shao, Ning Zhou, Ruiyi Zhang, Si Lu, Ziyi Zhou, Min Xie, Jiayang Wei, Ting Yu, Qian Liu, Runhui
- 机构：East China Univ Sci & Technol;Soochow Univ
- 来源：ACS APPLIED MATERIALS & INTERFACES 2019
- 关键词：beta-peptide polymer host defense peptide antimicrobial surface MRSA subcutaneous infection
- Silk-Inspired β-Peptide Materials Resist Fouling and the ForEIgn-Body Response被引量：82收藏
- 作者：Zhang, Donghui Chen, Qi Zhang, Wenjing Liu, Hengjiang Wan, Jianglin Qian, Yuxin Li, Bing Tang, Songchao Liu, Yu Chen, Shengfu Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Zhejiang Univ
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：materials science peptides polymers self-assembly surface chemistry
- Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications被引量：79收藏
- 作者：Wu, Yueming Chen, Kang Wang, Jiangzhou Chen, Minzhang Chen, Yuan She, Yunrui Yan, Zi Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：PROGRESS IN POLYMER SCIENCE 2023
- 关键词：Host defense peptides Antimicrobial amino acid polymers Antibiotic -resistant Polymerization methodology Antimicrobial drug candidates
- Advances in the antimicrobial treatment of osteomyelitis被引量：74收藏
- 作者：Zhong, Chao Wu, Yueming Lin, Haodong Liu, Runhui
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shanghai Gen Hosp;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：COMPOSITES PART B-ENGINEERING 2023
- 关键词：Osteomyelitis Antimicrobial agent therapy Physical therapy Immunotherapy
- Superfast and Water-Insensitive Polymerization on α-Amino Acid N-Carboxyanhydrides to Prepare Polypeptides Using Tetraalkylammonium Carboxylate as the Initiator被引量：73收藏
- 作者：Wu, Yueming Chen, Kang Wu, Xue Liu, Longqiang Zhang, Weiwei Ding, Yun Liu, Shiqi Zhou, Min Shao, Ning Ji, Zhemin Chen, Jiacheng Zhu, Minghui Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2021
- 关键词：antimicrobial aqueous polymerization in situ self-assembly NCA polymerization tetraalkylammonium carboxylate
- Peptide Polymer-Doped Cement Acting as an Effective Treatment of MRSA-Infected Chronic Osteomyelitis被引量：68收藏
- 作者：Wu, Yueming Lin, Yaofa Cong, Zihao Chen, Kang Xiao, Ximian Wu, Xue Liu, Longqiang She, Yunrui Liu, Shiqi Zhou, Ruiyi Yin, Gang Shao, Xiaoyan Dai, Yidong Lin, Haodong Liu, Runhui
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shanghai Gen Hosp;East China Univ Sci & Technol;Shanghai Ruijin Rehabil Hosp
- 来源：ADVANCED FUNCTIONAL MATERIALS 2022
- 关键词：antibacterial chronic osteomyelitis host defense peptides MRSA peptide polymers
- Recent Advances and Future Developments in the Preparation of Polypeptides via N-Carboxyanhydride (NCA) Ring-Opening Polymerization被引量：68收藏
- 作者：Wu, Yueming Chen, Kang Wang, Jiangzhou Chen, Minzhang Dai, Wenhui Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2024
- Heterochiral β-Peptide Polymers Combating Multidrug-Resistant Cancers Effectively without Inducing Drug Resistance被引量：67收藏
- 作者：Shao, Ning Yuan, Ling Ma, Pengcheng Zhou, Min Xiao, Ximian Cong, Zihao Wu, Yueming Xiao, Guohui Fei, Jian Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2022
- 关键词：Diseases - Biocompatibility - Cancer cells - Tumors
- Water-Insensitive Synthesis of Poly-β-Peptides with Defined Architecture被引量：66收藏
- 作者：Zhou, Min Xiao, Ximian Cong, Zihao Wu, Yueming Zhang, Wenjing Ma, Pengcheng Chen, Sheng Zhang, Haodong Zhang, Danfeng Zhang, Donghui Luan, Xiangfeng Mai, Yiyong Liu, Runhui
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：polymerization poly-beta-peptides secondary structure water-insensitive polymerization beta-NTA
- The impact of antifouling layers in fabricating bioactive surfaces被引量：61收藏
- 作者：Chen, Qi Zhang, Donghui Gu, Jiawei Zhang, Haodong Wu, Xue Cao, Chuntao Zhang, Xinyue Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACTA BIOMATERIALIA 2021
- 关键词：Fouling Antifouling PEG Bioactive surface Cell adhesion Functional peptides
- Single-Center Trifunctional Organocatalyst Enables Fast and Controlled Polymerization on N-Carboxyanhydride被引量：53收藏
- 作者：Chen, Kang Wu, Yueming Chen, Minzhang Wang, Jiangzhou Zhou, Min Chen, Xin Liu, Runhui
- 机构： State Key Laboratory of Bioreactor Engineering; Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism; Department of Biomaterials and Stem Cells; Key Laboratory for Ultrafine Materials
- 来源：ACS Central Science 2025
- 关键词：Carboxylation - Cationic polymerization - Organocatalyst - Reaction intermediates - Reaction rates - Ring opening polymerization
- Antimicrobial Properties and Application of Polysaccharides and ThEIr Derivatives被引量：51收藏
- 作者：Xia, Gui-Xue Wu, Yue-Ming Bi, Yu-Fang Chen, Kang Zhang, Wei-Wei Liu, Shi-Qi Zhang, Wen-Jing Liu, Run-Hui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHINESE JOURNAL OF POLYMER SCIENCE 2021
- 关键词：Antimicrobial Drug resistance Polysaccharides Polysaccharide derivatives Chitosan
- Quaternized Polysaccharide-Based Cationic Micelles as a Macromolecular Approach to Eradicate Multidrug-Resistant Bacterial Infections while Mitigating Antimicrobial Resistance被引量：51收藏
- 作者：Xie, Fang Jiang, Lai Xiao, Ximian Lu, Yiwen Liu, Runhui Jiang, Wei Cai, Jie
- 机构：Wuhan Univ;Wuhan Univ;East China Univ Sci & Technol;Wuhan Univ
- 来源：SMALL 2022
- 关键词：multidrug-resistant infection polysaccharides quaternization wound healing
- Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents被引量：48收藏
- 作者：Hovakeemian, Sara G. Liu, Runhui Gellman, Samuel H. Heerklotz, Heiko
- 机构：Univ Toronto;Univ Wisconsin;E China Univ Sci & Technol;E China Univ Sci & Technol;Univ Freiburg
- 来源：SOFT MATTER 2015
- 关键词：Yeast - Rayon - Polyamides - Lipid bilayers - Microorganisms - Soaps (detergents)
- Peptide-Mimicking Poly(2-oxazoline)s Possessing Potent Antifungal Activity and BBB Penetrating Property to Treat Invasive Infections and Meningitis被引量：47收藏
- 作者：Jiang, Weinan Zhou, Min Chen, Sheng Xie, Jiayang Chen, Minzhang Zhang, Haodong Wu, Yueming Chen, Xin Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2023
- 关键词：Antifungal agents - Drug interactions - Mammals - Peptides
- Peptide polymer displaying potent activity against clinically isolated multidrug resistant Pseudomonas aeruginosa in vitro and in vivo被引量：41收藏
- 作者：Jiang, Weinan Xiao, Ximian Wu, Yueming Zhang, Weiwei Cong, Zihao Liu, Jingjing Chen, Sheng Zhang, Haodong Xie, Jiayang Deng, Shuai Chen, Minzhang Wang, Yun Shao, Xiaoyan Dai, Yidong Sun, Yun Fei, Jian Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Ruijin Rehabil Hosp;Shanghai Jiao Tong Univ
- 来源：BIOMATERIALS SCIENCE 2020
- 关键词：Antimicrobial agents - Bacteria - Antibiotics - Lithium compounds - Network security
- Microbial Metabolite Inspired β-Peptide Polymers Displaying Potent and Selective Antifungal Activity被引量：41收藏
- 作者：Zhang, Donghui Shi, Chao Cong, Zihao Chen, Qi Bi, Yufang Zhang, Junyu Ma, Kaiqian Liu, Shiqi Gu, Jiawei Chen, Minzhang Lu, Ziyi Zhang, Haodong Xie, Jiayang Xiao, Ximian Liu, Longqiang Jiang, Weinan Shao, Ning Chen, Sheng Zhou, Min Shao, Xiaoyan Dai, Yidong Li, Maoquan Zhang, Lixin Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Ruijin Rehabil Hosp;Tongji Univ
- 来源：ADVANCED SCIENCE 2022
- 关键词：antifungal agents fungal keratitis host defense peptide mimicking poly(DL-diaminopropionic acid) beta-peptide polymers
- Structural design and antimicrobial properties of polypeptides and saccharide-polypeptide conjugates被引量：39收藏
- 作者：Wu, Yueming Xia, Guixue Zhang, Weiwei Chen, Kang Bi, Yufang Liu, Shiqi Zhang, Wenjing Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MATERIALS CHEMISTRY B 2020
- 关键词：Network security - Structural design - Biocompatibility - Losses - Microorganisms - Polypeptides
- Facile synthesis of N-phenoxycarbonyl amino acids by a two-phase reaction for direct polymerization被引量：37收藏
- 作者：Zhang, Donghui Liu, Shiqi Cai, Zhihao Luo, Weizhe Liu, Guojian Liu, Runhui
- 机构： State Key Laboratory of Bioreactor Engineering; School of Biotechnology; Key Laboratory for Ultrafine Materials of Ministry of Education
- 来源：Polymer Chemistry 2023
- 关键词：Column chromatography - Monomers - Polymerization
- Breaking or following the membrane-targeting mechanism: Exploring the antibacterial mechanism of host defense peptide mimicking poly(2-oxazoline)s被引量：36收藏
- 作者：Dai, Chengzhi Zhou, Min Jiang, Weinan Xiao, Ximian Zou, Jingcheng Qian, Yuxin Cong, Zihao Ji, Zhemin Liu, Longqiang Xie, Jiayang Qiao, Zhongqian Liu, Runhui
- 机构：East China Univ Sci & Technol;Fudan Univ
- 来源：JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 2020
- 关键词：Poly(2-oxazoline) Host defense peptide Antibacterial mechanism Membrane-targeting Antimicrobial resistance
