邵旭升 收藏
( 任职于 药学院)
邵旭升：博士，教授，博士生导师。2009年7月毕业于华东理工大学应用化学专业，导师李忠教授。2012年至2013年在美国加州大学伯克利分校John E. Casida教授课题组进行农药的毒理、代谢和作用机制研究。主要研究方向为植物化学保护、杀虫剂作用的生物学机制、杀虫剂作用靶酶的调控、基于光化学的农药化学生物学、杀虫剂的创制和应用。在PNAS、J. Agric. Food Chem.、Insect Biochem. Mol. Biol.、J. Org. Chem.等杂志发表SCI论文80多篇，其中第一或通讯作者论文40多篇；申请国内外专利39项，获中国专利授权6项，国外专利授权21项；是新... 详细>>
- Divalent and Oxabridged Neonicotinoids Constructed by Dialdehydes and Nitromethylene Analogues of Imidacloprid: Design, Synthesis, Crystal Structure, and Insecticidal Activities被引量：116收藏
- 作者：Shao, Xusheng Fu, Hua Xu, Xiaoyong Xu, Xinglei Liu, Zewen Li, Zhong Qian, Xuhong
- 机构：E China Univ Sci & Technol;Nanjing Agr Univ;Qinghai Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2010
- 关键词：Neonicotinoids dialdehydes imidacloprid insecticide oxabridge
- 质疑
- Overall status of neonicotinoid insecticides in China: Production, application and innovation被引量：112收藏
- 作者：Shao, Xusheng Liu, Zewen Xu, Xiaoyong Li, Zhong Qian, Xuhong
- 机构：E China Univ Sci & Technol;Nanjing Agr Univ
- 来源：JOURNAL OF PESTICIDE SCIENCE 2013
- 关键词：China neonicotinoid production application innovation
- 质疑
- Synthesis, insecticidal activity, and QSAR of novel nitromethylene neonicotinoids with tetrahydropyridine fixed cis configuration and exo-ring ether modification被引量：107收藏
- 作者：Tian, Zhongzhen Shao, Xusheng Li, Zhong Qian, Xuhong Huang, Qingchun
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2007
- 关键词：nitromethylene tetrahydropyridine cis position QSAR
- 质疑
- Ecological toxicity reduction of dinotefuran to honeybee: New perspective from an enantiomeric level被引量：95收藏
- 作者：Chen, Zenglong Yao, Xiangmei Dong, Fengshou Duan, Hongxia Shao, Xusheng Chen, Xiu Yang, Ting Wang, Guirong Zheng, Yongquan
- 机构：Chinese Acad Agr Sci;Chinese Acad Sci;China Agr Univ;East China Univ Sci & Technol
- 来源：ENVIRONMENT INTERNATIONAL 2019
- 关键词：Chiral neonicotinoid Toxicity reduction Dinotefuran enantiomers Enantioselective toxicology Honeybee
- 质疑
- Design, Synthesis, and Insecticidal Activities of Novel Analogues of Neonicotinoids: Replacement of Nitromethylene with Nitroconjugated System被引量：75收藏
- 作者：Shao, Xusheng Li, Zhong Qian, Xuhong Xu, Xiaoyong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2009
- 关键词：Neonicotinoids nitromethylene imidacloprid insecticide
- 质疑
- cis-Nitromethylene neonicotinoids as new nicotinic family: Synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-α]pyridine被引量：75收藏
- 作者：Shao, Xusheng Zhang, Wenwen Peng, Yanqing Li, Zhong Tian, Zhongzhen Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2008
- 关键词：Neonicotinoid cis-Configuration Insecticide Resistance
- 质疑
- cis-Configuration: A New Tactic/Rationale for Neonicotinoid Molecular Design被引量：70收藏
- 作者：Shao, Xusheng Lee, Philip W. Liu, Zewen Xu, Xiaoyong Li, Zhong Qian, Xuhong
- 机构：E China Univ Sci & Technol;Nanjing Agr Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2011
- 关键词：neonicotinoids cis-configuration insecticide selectivity
- 质疑
- Pyrrole- and Dihydropyrrole-Fused Neonicotinoids: Design, Synthesis, and Insecticidal Evaluation被引量：64收藏
- 作者：Ye, Zhenjun Shi, Lina Shao, Xusheng Xu, Xiaoyong Xu, Zhiping Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2013
- 关键词：Pyrrole dihydropyrrole neonicotinoid nAChR
- 质疑
- Specific Synergist for Neonicotinoid Insecticides: IPPA08, a cis-Neonicotinoid Compound with a Unique Oxabridged Substructure被引量：53收藏
- 作者：Bao, Haibo Shao, Xusheng Zhang, Yixi Deng, Yayun Xu, Xiaoyong Liu, Zewen Li, Zhong
- 机构：Nanjing Agr Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2016
- 关键词：neonicotinoid insecticide synergist detoxification enzyme nicotinic acetylcholine receptors
- 质疑
- Cis-configuration: A new tactic/rationale for neonicotinoid molecular design被引量：52收藏
- 作者：Shao, Xusheng Lee, Philip W. Liu, Zewen Xu, Xiaoyong Li, Zhong Qian, Xuhong
- 机构： Shanghai Key Laboratory of Chemical Biology; Key Laboratory of Monitoring and Management of Plant Disease and Insect
- 来源：Journal of Agricultural and Food Chemistry 2011
- 关键词：Organic compounds
- 质疑
- Fipronil induces apoptosis through caspase-dependent mitochondrial pathways in Drosophila S2 cells被引量：48收藏
- 作者：Zhang, Baoyan Xu, Zhiping Zhang, Yixi Shao, Xusheng Xu, Xiaoyong Cheng, Jiaogao Li, Zhong
- 机构：E China Univ Sci & Technol;Nanjing Agr Univ
- 来源：PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 2015
- 关键词：Fipronil Drosophila S2 cells Apoptosis Mitochondrion Caspase Cytochrome c
- 质疑
- Binding Difference of Fipronil with GABAARs in Fruitfly and Zebrafish: Insights from Homology Modeling, Docking, and Molecular Dynamics Simulation Studies被引量：44收藏
- 作者：Zheng, Nan Cheng, Jiagao Zhang, Wei Li, Weihua Shao, Xusheng Xu, Zhiping Xu, Xiaoyong Li, Zhong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2014
- 关键词：fipronil GABA(A) receptors homology modeling docking molecular dynamics simulation
- 质疑
- Insect nicotinic receptor interactions in vivo with neonicotinoid, organophosphorus, and methylcarbamate insecticides and a synergist被引量：42收藏
- 作者：Shao, Xusheng Xia, Shanshan Durkin, Kathleen A. Casida, John E.
- 机构：Univ Calif Berkeley;Univ Calif Berkeley;E China Univ Sci & Technol
- 来源：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2013
- 质疑
- Discovery of novel 1,5-benzodiazepine-2,4-dione derivatives as potential anticancer agents被引量：41收藏
- 作者：Chen, Yinbo Le, Vanminh Xu, Xiaoyong Shao, Xusheng Liu, Jianwen Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2014
- 关键词：1,5-Benzodiazepine-2,4-dione Anthranilic diamide Conformational restriction Synthesis Antitumor activity
- 质疑
- Degradation of chiral neonicotinoid insecticide cycloxaprid in flooded and anoxic soil被引量：40收藏
- 作者：Liu, Xuanqi Xu, Xiaoyong Li, Chao Zhang, Hanxue Fu, Qiuguo Shao, Xusheng Ye, Qingfu Li, Zhong
- 机构：E China Univ Sci & Technol;Zhejiang Univ
- 来源：CHEMOSPHERE 2015
- 关键词：Cycloxaprid Chiral Isotope labeling Soil degradation Dynamic Pathway
- 质疑
- Design, Synthesis, Crystal Structures, and Insecticidal Activities of Eight-Membered Azabridge Neonicotinoid Analogues被引量：39收藏
- 作者：Xu, Renbo Xia, Rui Luo, Ming Xu, Xiaoyong Cheng, Jiagao Shao, Xusheng Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2014
- 关键词：oxabridge azabridge neonicotinoids insecticide
- 质疑
- Phytoalexin Phenalenone Derivatives Inactivate Mosquito Larvae and Root-knot Nematode as Type-II Photosensitizer被引量：38收藏
- 作者：Song, Runjiang Feng, Yian Wang, Donghui Xu, Zhiping Li, Zhong Shao, Xusheng
- 机构：East China Univ Sci & Technol;Peking Univ
- 来源：SCIENTIFIC REPORTS 2017
- 质疑
- Tetrahydroindeno[1′,2′:4,5]pyrrolo[1,2-a]imidazol-5(1H)-ones as Novel Neonicotinoid Insecticides: Reaction Selectivity and Substituent Effects on the Activity Level被引量：37收藏
- 作者：Chen, Nanyang Meng, Xiaoqing Zhu, Fengjuan Cheng, Jiagao Shao, Xusheng Li, Zhong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2015
- 关键词：tetrahydroindeno[1 ',2 ':4,5]pyrrolo[1,2-a]imidazol-S(1H)-one insecticide activity synthesis
- 质疑
- Application of photopharmacology in agrochemicals被引量：35收藏
- 作者：Fu, Wen Li, Zhong Shao, Xusheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED AGROCHEM 2023
- 关键词：Photopharmacology Agrochemicals Photochromic ligands Optical control Ligand-receptor interactions
- 质疑
- Synthesis, Crystal Structure, and Insecticidal Activities of Highly Congested Hexahydroimidazo[1,2-a]pyridine Derivatives: Effect of Conformation on Activities被引量：35收藏
- 作者：Shao, Xusheng Xu, Zhiping Zhao, Xianfeng Xu, Xiaoyong Tao, Limin Zhong Li Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2010
- 关键词：Diels-Alder reaction insecticide conformation activities
- 质疑
- Novel Inhibitors of an Insect Pest Chitinase: Design and Optimization of 9-O-Aromatic and Heterocyclic Esters of Berberine被引量：34收藏
- 作者：Zhu, Ling Chen, Lei Shao, Xusheng Cheng, Jiagao Yang, Qing Qian, Xuhong
- 机构：East China Univ Sci & Technol;Chinese Acad Agr Sci;Chinese Acad Agr Sci;East China Univ Sci & Technol;East China Normal Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2021
- 关键词：Of Chi-h chitinase glycoside hydrolase inhibitor berberine pesticide
- 质疑
- Design and Synthesis of Novel Insecticides Based on the Serotonergic Ligand 1-[(4-Aminophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine (PAPP)被引量：34收藏
- 作者：Cai, Mingyi Zhong Li Feng Fan Huang, Qingchun Shao, Xusheng Song, Gonghua
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2010
- 关键词：PAPP 1-arylmethyl-4-[(trifluoromethyl)pyridin-2-yl]piperazine larvicidal activity growth inhibiting activity QSAR
- 质疑
- Green Pesticide R&D in China被引量：32收藏
- 作者：Li, Zhong Shao, Xusheng Lee, Philip W. Qian, Xuhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Normal Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2023
- 质疑
- Bioavailability and release of nonextractable (bound) residues of chiral cycloxaprid using geophagous earthworm Metaphire guillelmi in rice paddy soil被引量：31收藏
- 作者：Liu, Xuanqi Xu, Xiaoyong Zhang, Hanxue Li, Chao Shao, Xusheng Ye, Qingfu Li, Zhong
- 机构：E China Univ Sci & Technol;Zhejiang Univ
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2015
- 关键词：Cycloxaprid Enantiomers Bound residues Release Bioavailability Depuration
- 质疑
- Design, synthesis and insecticidal activity of spiro heterocycle containing neonicotinoid analogs被引量：31收藏
- 作者：Chen, Nan-Yang Ren, Li-Ping Zou, Min-Ming Xu, Zhi-Ping Shao, Xu-Sheng Xu, Xiao-Yong Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2014
- 关键词：Neonicotinoid Spiro heterocycle Activity Insecticide
- 质疑
- Advanced Research on cis-Neonicotinoids被引量：30收藏
- 作者：Shao, Xusheng Ye, Zhejun Bao, Haibo Li, Zewen Xu, Xiaoyong Li, Zhong Qian, Xuhong
- 机构：E China Univ Sci & Technol;Nanjing Agr Univ
- 来源：CHIMIA 2011
- 关键词：Activity Insecticide cis-Neonicotinoids
- 质疑
- One-pot synthesis of polyfunctionalized 4H-pyran derivatives bearing fluorochloro pyridyl moiety被引量：30收藏
- 作者：Ye, Zhenjun Xu, Renbo Shao, Xusheng Xu, Xiaoyong Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2010
- 关键词：4H-Pyran derivatives Fluorochloro pyridyl Multicomponent reactions (MCRs)
- 质疑
- Synthesis and Biological Activity of Novel Antifungal Leads: 3,5-Dichlorobenzyl Ester Derivatives被引量：29收藏
- 作者：Du, Shaoqing Yuan, Qinglong Hu, Xueping Fu, Wen Xu, Qi Wei, Ziyi Xu, Jiazheng Shao, Xusheng Qian, Xuhong
- 机构：East China Univ Sci & Technol;Zhejiang Univ;East China Normal Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2021
- 关键词：succinate dehydrogenase inhibitors fungicidal activity molecular dynamic simulations 3,5-dichlorobenzyl ester
- 质疑
- Design, Synthesis, and Particular Biological Behaviors of Chain-Opening Nitromethylene Neonicotinoids with Cis Configuration被引量：29收藏
- 作者：Lu, Siyuan Shao, Xusheng Li, Zhong Xu, Zhiping Zhao, Shishuai Wu, Yinli Xu, Xiaoyong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2012
- 关键词：chain-opening neonicotinoids repellent effects cis configuration tetrahydropyridine
- 质疑
- Reversible Regulation of Succinate Dehydrogenase by Tools of Photopharmacology被引量：28收藏
- 作者：Fu, Wen Shao, Zhongli Sun, Xujuan Zhou, Cong Xu, Zhiping Zhang, Yang Cheng, Jiagao Li, Zhong Shao, Xusheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2022
- 关键词：regulation SDH photochromic ligands azobenzene optical control
- 质疑
