徐晓勇 收藏
( 任职于 药学院)
1970年出生，2003年聘为硕士生导师，2002年被聘为副教授，2008年被聘为教授。2003年获华东理工大学应用化学专业工学博士学位，1997年获华东理工大学精细化工专业工学硕士学位，1992年获华东理工大学腐蚀与防护专业工学学士学位。 作为课题负责人承担了国家自然科学基金一项，科技部“十一五”科技支撑项目一项，上海市科委科技攻关项目2项，上海市重点实验室专项基金一项，作为项目组成员参加国家“973”计划项目一项，作为项目主要研究人员参加国家“863”高科技攻关项... 详细>>
- Divalent and Oxabridged Neonicotinoids Constructed by Dialdehydes and Nitromethylene Analogues of Imidacloprid: Design, Synthesis, Crystal Structure, and Insecticidal Activities被引量：116收藏
- 作者：Shao, Xusheng Fu, Hua Xu, Xiaoyong Xu, Xinglei Liu, Zewen Li, Zhong Qian, Xuhong
- 机构：E China Univ Sci & Technol;Nanjing Agr Univ;Qinghai Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2010
- 关键词：Neonicotinoids dialdehydes imidacloprid insecticide oxabridge
- 质疑
- Overall status of neonicotinoid insecticides in China: Production, application and innovation被引量：112收藏
- 作者：Shao, Xusheng Liu, Zewen Xu, Xiaoyong Li, Zhong Qian, Xuhong
- 机构：E China Univ Sci & Technol;Nanjing Agr Univ
- 来源：JOURNAL OF PESTICIDE SCIENCE 2013
- 关键词：China neonicotinoid production application innovation
- 质疑
- Design, Synthesis, and Insecticidal Activities of Novel Analogues of Neonicotinoids: Replacement of Nitromethylene with Nitroconjugated System被引量：75收藏
- 作者：Shao, Xusheng Li, Zhong Qian, Xuhong Xu, Xiaoyong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2009
- 关键词：Neonicotinoids nitromethylene imidacloprid insecticide
- 质疑
- cis-Configuration: A New Tactic/Rationale for Neonicotinoid Molecular Design被引量：70收藏
- 作者：Shao, Xusheng Lee, Philip W. Liu, Zewen Xu, Xiaoyong Li, Zhong Qian, Xuhong
- 机构：E China Univ Sci & Technol;Nanjing Agr Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2011
- 关键词：neonicotinoids cis-configuration insecticide selectivity
- 质疑
- Separation of carbohydrates using hydrophilic interaction liquid chromatography被引量：65收藏
- 作者：Fu, Qing Liang, Tu Li, Zhenyu Xu, Xiaoyong Ke, Yanxiong Jin, Yu Liang, Xinmiao
- 机构：E China Univ Sci & Technol
- 来源：CARBOHYDRATE RESEARCH 2013
- 关键词：Carbohydrates Hydrophilic interaction liquid chromatography Stationary phase Selectivity Chromatographic characterization
- 质疑
- Pyrrole- and Dihydropyrrole-Fused Neonicotinoids: Design, Synthesis, and Insecticidal Evaluation被引量：64收藏
- 作者：Ye, Zhenjun Shi, Lina Shao, Xusheng Xu, Xiaoyong Xu, Zhiping Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2013
- 关键词：Pyrrole dihydropyrrole neonicotinoid nAChR
- 质疑
- An Efficient One-Pot Synthesis of Substituted 2-Aminothiophenes via Three-Component Gewald Reaction Catalyzed by L-Proline被引量：62收藏
- 作者：Wang, Tao Huang, Xian-Gui Liu, Jia Li, Bo Wu, Jin-Jin Chen, Kai-Xian Zhu, Wei-Liang Xu, Xiao-Yong Zeng, Bu-Bing
- 机构：E China Univ Sci & Technol;Shanghai Key Lab Chem Biol;Shanghai Inst Mat Med;Shanghai Univ Tradit Chinese Med
- 来源：SYNLETT 2010
- 关键词：Gewald reaction 2-aminothiophene one-pot multi-component Knoevenagel reaction
- 质疑
- Synthesis and Nematicidal Activities of 1,2,3-Benzotriazin-4-one Derivatives against Meloidogyne incognita被引量：57收藏
- 作者：Wang, Gaolei Chen, Xiulei Deng, Yayun Li, Zhong Xu, Xiaoyong
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2015
- 关键词：1,2,3-benzotriazin-4-one 2-cyanoiminothiazolidin-4-one nematicide Meloidogyne incognita in vivo
- 质疑
- The thiazoylmethoxy modification on pyrazole oximes: Synthesis and insecticidal biological evaluation beyond acaricidal activity被引量：56收藏
- 作者：Dai, Hong Xiao, Yan-Shuang Li, Zhong Xu, Xiao-Yong Qian, Xu-Hong
- 机构：E China Univ Sci & Technol;Nantong Univ
- 来源：CHINESE CHEMICAL LETTERS 2014
- 关键词：Pyrazole oxime Substituted thiazole Acaricidal activity Insecticidal activity
- 质疑
- Specific Synergist for Neonicotinoid Insecticides: IPPA08, a cis-Neonicotinoid Compound with a Unique Oxabridged Substructure被引量：53收藏
- 作者：Bao, Haibo Shao, Xusheng Zhang, Yixi Deng, Yayun Xu, Xiaoyong Liu, Zewen Li, Zhong
- 机构：Nanjing Agr Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2016
- 关键词：neonicotinoid insecticide synergist detoxification enzyme nicotinic acetylcholine receptors
- 质疑
- Cis-configuration: A new tactic/rationale for neonicotinoid molecular design被引量：52收藏
- 作者：Shao, Xusheng Lee, Philip W. Liu, Zewen Xu, Xiaoyong Li, Zhong Qian, Xuhong
- 机构： Shanghai Key Laboratory of Chemical Biology; Key Laboratory of Monitoring and Management of Plant Disease and Insect
- 来源：Journal of Agricultural and Food Chemistry 2011
- 关键词：Organic compounds
- 质疑
- Fipronil induces apoptosis through caspase-dependent mitochondrial pathways in Drosophila S2 cells被引量：48收藏
- 作者：Zhang, Baoyan Xu, Zhiping Zhang, Yixi Shao, Xusheng Xu, Xiaoyong Cheng, Jiaogao Li, Zhong
- 机构：E China Univ Sci & Technol;Nanjing Agr Univ
- 来源：PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 2015
- 关键词：Fipronil Drosophila S2 cells Apoptosis Mitochondrion Caspase Cytochrome c
- 质疑
- Binding Difference of Fipronil with GABAARs in Fruitfly and Zebrafish: Insights from Homology Modeling, Docking, and Molecular Dynamics Simulation Studies被引量：44收藏
- 作者：Zheng, Nan Cheng, Jiagao Zhang, Wei Li, Weihua Shao, Xusheng Xu, Zhiping Xu, Xiaoyong Li, Zhong
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2014
- 关键词：fipronil GABA(A) receptors homology modeling docking molecular dynamics simulation
- 质疑
- Discovery of novel 1,5-benzodiazepine-2,4-dione derivatives as potential anticancer agents被引量：41收藏
- 作者：Chen, Yinbo Le, Vanminh Xu, Xiaoyong Shao, Xusheng Liu, Jianwen Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2014
- 关键词：1,5-Benzodiazepine-2,4-dione Anthranilic diamide Conformational restriction Synthesis Antitumor activity
- 质疑
- Degradation of chiral neonicotinoid insecticide cycloxaprid in flooded and anoxic soil被引量：40收藏
- 作者：Liu, Xuanqi Xu, Xiaoyong Li, Chao Zhang, Hanxue Fu, Qiuguo Shao, Xusheng Ye, Qingfu Li, Zhong
- 机构：E China Univ Sci & Technol;Zhejiang Univ
- 来源：CHEMOSPHERE 2015
- 关键词：Cycloxaprid Chiral Isotope labeling Soil degradation Dynamic Pathway
- 质疑
- Design, Synthesis, Crystal Structures, and Insecticidal Activities of Eight-Membered Azabridge Neonicotinoid Analogues被引量：39收藏
- 作者：Xu, Renbo Xia, Rui Luo, Ming Xu, Xiaoyong Cheng, Jiagao Shao, Xusheng Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2014
- 关键词：oxabridge azabridge neonicotinoids insecticide
- 质疑
- Novel perfluoroalkyl phthalocyanine metal derivatives: Synthesis and photodynamic activities被引量：38收藏
- 作者：Qiu, Tao Xu, Xiaoyong Liu, Jianwen Qian, Xuhong
- 机构：E China Univ Sci & Technol;Jiangsu Polytech Univ
- 来源：DYES AND PIGMENTS 2009
- 关键词：Perfluoroalkyl phthalocyanines Synthesis Photosensitizer Photodynamic therapy HL-60 leukemic cell A375 melanotic cancer cell
- 质疑
- Synthesis, nematicidal activity and docking study of novel chromone derivatives containing substituted pyrazole被引量：36收藏
- 作者：Li, Wei Li, Jiuhui Shen, Hongfeng Cheng, Jiagao Li, Zhong Xu, Xiaoyong
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：CHINESE CHEMICAL LETTERS 2018
- 关键词：Chromone Substituted pyrazole Meloidogyne incognita Nematicidal activity Molecular docking
- 质疑
- Stereoisomeric Isolation and Stereoselective Fate of Insecticide Paichongding in Flooded Paddy Soils被引量：36收藏
- 作者：Li, Juying Zhang, Jianbo Li, Chao Wang, Wei Yang, Zhen Wang, Haiyan Gan, Jay Ye, Qingfu Xu, Xiaoyong Li, Zhong
- 机构：Zhejiang Univ;E China Univ Sci & Technol;Univ Calif Riverside
- 来源：ENVIRONMENTAL SCIENCE & TECHNOLOGY 2013
- 关键词：Mineralogy - Insecticides - Floods - Stereoselectivity - Soils
- 质疑
- Synthesis, Crystal Structure, and Insecticidal Activities of Highly Congested Hexahydroimidazo[1,2-a]pyridine Derivatives: Effect of Conformation on Activities被引量：35收藏
- 作者：Shao, Xusheng Xu, Zhiping Zhao, Xianfeng Xu, Xiaoyong Tao, Limin Zhong Li Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2010
- 关键词：Diels-Alder reaction insecticide conformation activities
- 质疑
- Bioisosterism and Scaffold Hopping in Modern Nematicide Research被引量：35收藏
- 作者：Cao, Xiaofeng Yang, Haiping Liu, Cheng Zhang, Ruifeng Maienfisch, Peter Xu, Xiaoyong
- 机构：East China Univ Sci & Technol;CreInSol Consulting Biocontrols
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2022
- 关键词：bioisosterism molecular design nematicidal activity fluensulfone sulfone amide replacement chain extension reversal of amide group
- 质疑
- 二十一世纪新农药研发趋势被引量：33收藏
- 作者：钱旭红 徐晓勇 宋恭华 李忠
- 机构：大连理工大学精细化工国家重点实验室;华东理工大学药物化工研究所
- 来源：《贵州大学学报（自然科学版）》 2003
- 关键词：二十一世纪 农药研发 研究方法 开发方式 生物合理设计原理 靶标 杂环化合物
- 摘要：综述了二十一世纪新农药开发的主要方式和特点 ,采用高效率的研究方法和手段 ,利用生物合理设计原理 ,针对酶及其它更多新的作用靶标 ,设计开发杂环化合物是新农药的研究和开发趋势。
- 下载全文在线阅读质疑
- Diastereoselective Metabolism of a Novel Cis-Nitromethylene Neonicotinoid Paichongding in Aerobic Soils被引量：32收藏
- 作者：Fu, Qiuguo Zhang, Jianbo Xu, Xiaoyong Wang, Haiyan Wang, Wei Ye, Qingfu Li, Zhong
- 机构：Zhejiang Univ;E China Univ Sci & Technol
- 来源：ENVIRONMENTAL SCIENCE & TECHNOLOGY 2013
- 关键词：Nitrogen removal - Stereoselectivity
- 质疑
- Bioavailability and release of nonextractable (bound) residues of chiral cycloxaprid using geophagous earthworm Metaphire guillelmi in rice paddy soil被引量：31收藏
- 作者：Liu, Xuanqi Xu, Xiaoyong Zhang, Hanxue Li, Chao Shao, Xusheng Ye, Qingfu Li, Zhong
- 机构：E China Univ Sci & Technol;Zhejiang Univ
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2015
- 关键词：Cycloxaprid Enantiomers Bound residues Release Bioavailability Depuration
- 质疑
- Design, synthesis and insecticidal activity of spiro heterocycle containing neonicotinoid analogs被引量：31收藏
- 作者：Chen, Nan-Yang Ren, Li-Ping Zou, Min-Ming Xu, Zhi-Ping Shao, Xu-Sheng Xu, Xiao-Yong Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2014
- 关键词：Neonicotinoid Spiro heterocycle Activity Insecticide
- 质疑
- Advanced Research on cis-Neonicotinoids被引量：30收藏
- 作者：Shao, Xusheng Ye, Zhejun Bao, Haibo Li, Zewen Xu, Xiaoyong Li, Zhong Qian, Xuhong
- 机构：E China Univ Sci & Technol;Nanjing Agr Univ
- 来源：CHIMIA 2011
- 关键词：Activity Insecticide cis-Neonicotinoids
- 质疑
- One-pot synthesis of polyfunctionalized 4H-pyran derivatives bearing fluorochloro pyridyl moiety被引量：30收藏
- 作者：Ye, Zhenjun Xu, Renbo Shao, Xusheng Xu, Xiaoyong Li, Zhong
- 机构：E China Univ Sci & Technol
- 来源：TETRAHEDRON LETTERS 2010
- 关键词：4H-Pyran derivatives Fluorochloro pyridyl Multicomponent reactions (MCRs)
- 质疑
- Versatile and mild synthesis of Di- and trisaccharidic 2-enopyranosyl cyanides by cyanation of per-O-acetylglycals with trimethylsilyl cyanide catalyzed by palladium(II) acetate被引量：30收藏
- 作者：Xu, Xiaoyong Tan, Qitao Hayashi, Masahiko
- 机构： Department of Frontier Research and Technology; Department of Chemistry; Shanghai Key Lab. of Chemical Biology
- 来源：Synthesis 2008
- 关键词：Catalyst activity - Oligosaccharides - Palladium - Stereoselectivity - Synthesis (chemical)
- 质疑
- Design, Synthesis, and Particular Biological Behaviors of Chain-Opening Nitromethylene Neonicotinoids with Cis Configuration被引量：29收藏
- 作者：Lu, Siyuan Shao, Xusheng Li, Zhong Xu, Zhiping Zhao, Shishuai Wu, Yinli Xu, Xiaoyong
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2012
- 关键词：chain-opening neonicotinoids repellent effects cis configuration tetrahydropyridine
- 质疑
- Design, Multicomponent Synthesis, and Bioactivities of Novel Neonicotinoid Analogues with 1,4-Dihydropyridine Scaffold被引量：28收藏
- 作者：Zhang, Wenwen Yang, Xiaobao Chen, Weidong Xu, Xiaoyong Li, Lu Zhai, Hongbin Li, Zhong
- 机构：Chinese Acad Sci;E China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2010
- 关键词：1,4-Dihydropridine MCRs biological activity
- 质疑
