- Production of Succinate from Acetate by Metabolically Engineered Escherichia coli被引量：90收藏
- 作者：Li, Yunjie Huang, Bing Wu, Hui Li, Zhimin Ye, Qin Zhang, Y-H Percival
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;Virginia Tech;Chinese Acad Sci
- 来源：ACS SYNTHETIC BIOLOGY 2016
- 关键词：acetate succinate metabolic engineering Escherichia coli malic enzyme citrate synthase
- 质疑
- Improved succinic acid production in the anaerobic culture of an Escherichia coli PflB ldhA double mutant as a result of enhanced anaplerotic activities in the preceding aerobic culture被引量：89收藏
- 作者：Wu, Hui Li, Zhi-Min Zhou, Li Ye, Qin
- 机构：E China Univ Chem Technol
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2007
- 质疑
- Systematic manipulation of glutathione metabolism in Escherichia coli for improved glutathione production被引量：85收藏
- 作者：Zhang, Jing Quan, Cong Wang, Cheng Wu, Hui Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：MICROBIAL CELL FACTORIES 2016
- 关键词：Escherichia coli Glutathione Systematic manipulation Bifunctional glutathione synthetase Fed-batch fermentation
- 质疑
- Simultaneous production of 3-hydroxypropionic acid and 1,3-propanediol from glycerol by a recombinant strain of Klebsiella pneumoniae被引量：84收藏
- 作者：Huang, Yanna Li, Zhimin Shimizu, Kazuyuki Ye, Qin
- 机构：E China Univ Sci & Technol;Kyushu Inst Technol
- 来源：BIORESOURCE TECHNOLOGY 2012
- 关键词：3-Hydroxypropionic acid 1,3-Propanediol Klebsiella pneumoniae Aldehyde dehydrogenase
- 质疑
- Co-production of 3-hydroxypropionic acid and 1,3-propanediol by Klebseilla pneumoniae expressing aldH under microaerobic conditions被引量：67收藏
- 作者：Huang, Yanna Li, Zhimin Shimizu, Kazuyuki Ye, Qin
- 机构：E China Univ Sci & Technol;Kyushu Inst Technol
- 来源：BIORESOURCE TECHNOLOGY 2013
- 关键词：3-Hydroxypropionic acid 1,3-Propanediol Klebsiella pneumoniae Aldehyde dehydrogenase Aeration
- 质疑
- Central pathway engineering for enhanced succinate biosynthesis from acetate in Escherichia coli被引量：62收藏
- 作者：Huang, Bing Yang, Hao Fang, Guochen Zhang, Xing Wu, Hui Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2018
- 关键词：acetate cofactor engineering Escherichia coli metabolic engineering succinate
- 质疑
- Bioethanol production from starchy biomass by direct fermentation using Saccharomyces diastaticus in batch free and immobilized cell systems被引量：57收藏
- 作者：Kilonzo, Peter M. Margaritis, Argyrios Yu, Juntang Ye, Qin
- 机构： Department of Chemical and Biochemical Engineering; Biochemical Engineering Research Institute
- 来源：International Journal of Green Energy 2007
- 关键词：Biomass - Bioreactors - Cell immobilization - Conversion efficiency - Fermentation - Starch - Yeast
- 质疑
- Development of succinic acid production from corncob hydrolysate by Actinobacillus succinogenes被引量：54收藏
- 作者：Yu, Jie Li, Zhimin Ye, Qin Yang, Yong Chen, Shulin
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2010
- 关键词：Actinobacillus succinogenes Succinic acid Corncob hydrolysate Xylose Optimization
- 质疑
- Catabolic regulation analysis of Escherichia coli and its crp, mlc, mgsA, pgi and ptsG mutants被引量：52收藏
- 作者：Yao, Ruilian Hirose, Yuki Sarkar, Dayanidhi Nakahigashi, Kenji Ye, Qin Shimizu, Kazuyuki
- 机构：Kyushu Inst Technol;E China Univ Sci & Technol;Keio Univ
- 来源：MICROBIAL CELL FACTORIES 2011
- 质疑
- Enhanced succinate production from glycerol by engineered Escherichia coli strains被引量：47收藏
- 作者：Li, Qing Wu, Hui Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCE TECHNOLOGY 2016
- 关键词：Succinate Escherichia coli Glycerol Phosphoenolpyruvate carboxykinase Two-stage fermentation
- 质疑
- Simultaneous saccharification and fermentation of cassava to succinic acid by Escherichia coli NZN111被引量：46收藏
- 作者：Chen, Cuixia Ding, Shaopeng Wang, Dezheng Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2014
- 关键词：Succinic acid Simultaneous saccharification and fermentation Cassava Escherichia coli NZN111
- 质疑
- Enhanced production of 3-hydroxypropionic acid from glucose via malonyl-CoA pathway by engineered Escherichia coli被引量：45收藏
- 作者：Cheng, Zhuan Jiang, Jiaqi Wu, Hui Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIORESOURCE TECHNOLOGY 2016
- 关键词：3-Hydroxypropionate Acetyl-CoA carboxylase Malonyl-CoA reductase Corynebacterium glutamicum Escherichia coli
- 质疑
- L-Cysteine Production in Escherichia coli Based on Rational Metabolic Engineering and Modular Strategy被引量：43收藏
- 作者：Liu, Han Fang, Guochen Wu, Hui Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council
- 来源：BIOTECHNOLOGY JOURNAL 2018
- 关键词：Escherichia coli L-cysteine modular strategy rational metabolic engineering
- 质疑
- One-pot synthesis of glutathione by a two-enzyme cascade using a thermophilic ATP regeneration system被引量：43收藏
- 作者：Zhang, Xing Wu, Hui Huang, Bing Li, Zhimin Ye, Qin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2017
- 关键词：Glutathione Bifunctional glutathione synthetase ATP regeneration Polyphosphate Polyphosphate kinase
- 质疑
- Heterologous expression and characterization of a novel thermo-halotolerant endoglucanase Cel5H from Dictyoglomus thermophilum被引量：41收藏
- 作者：Shi, Runrun Li, Zhimin Ye, Qin Xu, Jianhe Liu, Yan
- 机构：E China Univ Sci & Technol;Michigan State Univ
- 来源：BIORESOURCE TECHNOLOGY 2013
- 关键词：Endoglucanase Thermostability Halo-tolerance Cellulose binding module Homology modeling
- 质疑
- Biosynthesis of trans-4-hydroxyproline by recombinant strains of Corynebacterium glutamicum and Escherichia coli被引量：40收藏
- 作者：Yi, Yulan Sheng, Huakai Li, Zhimin Ye, Qin
- 机构：E China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomanufacturing
- 来源：BMC BIOTECHNOLOGY 2014
- 关键词：Trans-4-hydroxy-L-proline Recombinant Corynebacterium glutamicum Recombinant Escherichia coli Proline 4-hydroxylases
- 质疑
- Characterization of a new lysine decarboxylase from Aliivibrio salmonicida for cadaverine production at alkaline pH被引量：40收藏
- 作者：Kou, Fengyu Zhao, Jing Liu, Jiao Shen, Jie Ye, Qin Zheng, Ping Li, Zhimin Sun, Jibin Ma, Yanhe
- 机构： State Key Laboratory of Bioreactor Engineering; Key Laboratory of Systems Microbial Biotechnology; Tianjin Institute of Industrial Biotechnology
- 来源：Journal of Molecular Catalysis B: Enzymatic 2016
- 关键词：Alkalinity - Amino acids
- 质疑
- Enhanced 1,3-propanediol production by supply of organic acids and repeated fed-batch culture被引量：39收藏
- 作者：Xue, Xuedong Li, Wei Li, Zhimin Xia, Yuelan Ye, Qin
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2010
- 关键词：1,3-Propanediol Organic acid mixture Repeated fed-batch culture Klebsiella pneumoniae
- 质疑
- Production of glutathione using a bifunctional enzyme encoded by gshF from Streptococcus thermophilus expressed in Escherichia coli被引量：37收藏
- 作者：Li, Wei Li, Zhimin Yang, Jianhua Ye, Qin
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2011
- 关键词：Glutathione Bifunctional glutathione synthetase Feedback inhibition ATP regeneration system
- 质疑
- Serum-Free Suspension Culture of MDCK Cells for Production of Influenza H1N1 Vaccines被引量：36收藏
- 作者：Huang, Ding Peng, Wen-Juan Ye, Qian Liu, Xu-Ping Zhao, Liang Fan, Li Xia-Hou, Kang Jia, Han-Jing Luo, Jian Zhou, Lin-Ting Li, Bei-Bei Wang, Shi-Lei Xu, Wen-Ting Chen, Ze Tan, Wen-Song
- 机构：E China Univ Sci & Technol;Shanghai Inst Biol Prod Co Ltd
- 来源：PLOS ONE 2015
- 质疑
- Crosslinking of enzyme coaggregate with polyethyleneimine: A simple and promising method for preparing stable biocatalyst of Serratia marcescens lipase被引量：35收藏
- 作者：Pan, Jiang Kong, Xu-Dong Li, Chun-Xiu Ye, Qin Xu, Jian-He Imanaka, Tadayuki
- 机构：E China Univ Sci & Technol;Ritsumeikan Univ
- 来源：JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 2011
- 关键词：Crosslinked enzyme coaggregate Serratia marcescens lipase Polyethyleneimine Coaggregation of enzyme trans-3-(4 '-Methoxyphenyl)glycidic acid methyl ester (MPGM)
- 质疑
- Enhanced production of human epidermal growth factor under control of the phoA promoter by acetate-tolerant Escherichia coli DB15 in a chemically defined medium被引量：35收藏
- 作者：Zhang, Yanjun Li, Zhimin Ye, Qin
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Biotechnology and Bioprocess Engineering 2010
- 关键词：Chlorine compounds - Gene expression - Escherichia coli - Dissolved oxygen
- 质疑
- Improved succinic acid production in the anaerobic culture of an Escherichia coli pflB ldhA double mutant as a result of enhanced anaplerotic activities in the preceding aerobic culture被引量：35收藏
- 作者：Wu, Hui Li, Zhi-Min Zhou, Li Ye, Qin
- 机构： State Key Laboratory of Bioreactor Engineering; State Key Laboratory of Bioreactor Engineering
- 来源：Applied and Environmental Microbiology 2007
- 关键词：Cell culture - Enzyme activity - Genetic engineering - Glucose - Metabolism - Mutagenesis
- 质疑
- Succinic acid production and CO2 fixation using a metabolically engineered Escherichia coli in a bioreactor equipped with a self-inducing agitator被引量：35收藏
- 作者：Wu, Hui Li, Qing Li, Zhi-Min Ye, Qin
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Bioresource Technology 2012
- 关键词：Escherichia coli - Bioconversion - Bioreactors - Ethanol - Fermentation
- 质疑
- 人工神经网络在红霉素发酵过程状态预估中的应用被引量：34收藏
- 作者：黄明志 杭海峰 储炬 叶勤 张嗣良
- 机构：华东理工大学生物反应器工程国家重点实验室
- 来源：《华东理工大学学报（自然科学版）》 2000
- 关键词：神经网络 BP网络 RBF网络 红霉素 发酵 状态预估
- 摘要：探索了动态 BP网络和 RBF网络在红霉素发酵过程状态预估中的应用 ,比较了它们的收敛速度和学习能力。结果表明 ,BP网络和 RBF网络都具有相当好的学习能力 ,但 RBF网络的收敛速度更快。训练好的神经网络 ,在红霉素...
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- Simultaneous production of 3-hydroxypropionic acid and 1,3-propanediol from glycerol by a recombinant strain of Klebsiella pneumoniae被引量：34收藏
- 作者：Huang, Yanna Li, Zhimin Shimizu, Kazuyuki Ye, Qin
- 机构： State Key Laboratory of Bioreactor Engineering; Department of Bioscience and Bioinformatics
- 来源：Bioresource Technology 2012
- 关键词：Escherichia coli - Batch cell culture - Aldehydes - Cloning - Gene expression
- 质疑
- Enhanced anaerobic succinic acid production by Escherichia coli NZN111 aerobically grown on gluconeogenic carbon sources被引量：33收藏
- 作者：Wu, Hui Li, Zhi-min Zhou, Li Xie, Jingli Ye, Qin
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Enzyme and Microbial Technology 2009
- 关键词：Sodium bicarbonate - Enzymes - Molecular biology - Cells - Carbon - Glucose - Cytology
- 质疑
- Effects of geometrical design on hydrodynamic and mass transfer characteristics of a rectangular-column airlift bioreactor被引量：32收藏
- 作者：Kilonzo, Peter M. Margaritis, Argyrios Bergougnou, M.A. Yu, Juntang Ye, Qin
- 机构：Univ Western Ontario;E China Univ Sci & Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2007
- 关键词：airlift bioreactor clearance gas holdup liquid velocity pressure drop mass transfer
- 质疑
- Efficient production of l-menthol in a two-phase system with SDS using an immobilized bacillus subtilis esterase被引量：32收藏
- 作者：Pan, Jiang Dang, Ngoc-Duy Zheng, Gao-Wei Cheng, Bo Ye, Qin Xu, Jian-He
- 机构： Laboratory of Biocatalysis and Synthetic Biotechnology; Sunflower Pharmaceutical Group Company Limited
- 来源：Bioresources and Bioprocessing 2014
- 关键词：Cloning - Crosslinking - Enantioselectivity - Enzymatic hydrolysis - Enzyme activity - Enzyme inhibition - Esters - Sulfur compounds
- 质疑
- Metabolic engineering of Escherichia coli carrying the hybrid acetone-biosynthesis pathway for efficient acetone biosynthesis from acetate被引量：32收藏
- 作者：Yang, Hao Huang, Bing Lai, Ningyu Gu, Yang Li, Zhimin Ye, Qin Wu, Hui
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol;China Natl Light Ind Council;Chinese Acad Sci
- 来源：MICROBIAL CELL FACTORIES 2019
- 关键词：Acetate Acetone Metabolic engineering Escherichia coli Gas-stripping Resting cell
- 质疑
