成果/Result
- Recent progress on molecularly near-infrared fluorescent probes for chemotherapy and phototherapy被引量：165收藏
- 作者：Yan, Chenxu Zhang, Yutao Guo, Zhiqian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：COORDINATION CHEMISTRY REVIEWS 2021
- 关键词：Near-infrared Fluorescent probe Prodrug Photodynamic therapy Photothermal therapy
- A Sequential Dual-Lock Strategy for Photoactivatable Chemiluminescent Probes Enabling Bright Duplex Optical Imaging被引量：120收藏
- 作者：Zhang, Yutao Yan, Chenxu Wang, Chao Guo, Zhiqian Liu, Xiaogang Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Singapore Univ Technol & Design
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2020
- 关键词：aggregation-induced emission chemiluminescent probes dual-mode bioimaging fluorescence probes sequential dual-lock
- Enzyme-activatable fluorescent probes for β-galactosidase: from design to biological applications被引量：113收藏
- 作者：Yao, Yongkang Zhang, Yutao Yan, Chenxu Zhu, Wei-Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2021
- 关键词：Enzymes - Probes - Diseases
- Rational design of a fast and selective near-infrared fluorescent probe for targeted monitoring of endogenous nitric oxide被引量：70收藏
- 作者：Tang, Junma Guo, Zhiqian Zhang, Yutao Bai, Bing Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2017
- Harnessing Hypoxia-Dependent Cyanine Photocages for In Vivo Precision Drug Release被引量：49收藏
- 作者：Zhang, Yutao Yan, Chenxu Zheng, Qiaoqiao Jia, Qian Wang, Zhongliang Shi, Ping Guo, Zhiqian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Xidian Univ
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2021
- 关键词：cyanine fluorescence imaging hypoxia-dependent photolysis near-infrared photocages photoacoustic imaging
- Bent-to-planar Si-rhodamines: a distinct rehybridization lights up NIR-II fluorescence for tracking nitric oxide in the Alzheimer's disease brain被引量：44收藏
- 作者：Xu, Qingshuang Zhang, Yutao Zhu, Mingming Yan, Chenxu Mao, Wenle Zhu, Wei-Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：CHEMICAL SCIENCE 2023
- 关键词：Clinical research - Fluorescence - Infrared devices - Mammals - Neurodegenerative diseases - Nitric oxide - Silicon - Silicon compounds
- Near-Infrared Aggregation-Induced Emission-Active Probe Enables in situ and Long-Term Tracking of Endogenous β-Galactosidase Activity被引量：43收藏
- 作者：Fu, Wei Yan, Chenxu Zhang, Yutao Ma, Yiyu Guo, Zhiqian Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol
- 来源：FRONTIERS IN CHEMISTRY 2019
- 关键词：fluorescent probe near-infrared aggregation-induced emission beta-galactosidase in situ long-term tracking
- Engineering high-performance dicyanomethylene-4H-pyran fluorophores for biosensing and phototherapy被引量：39收藏
- 作者：Liu, Qiang Sun, Chuyang Dai, Ruilong Yan, Chenxu Zhang, Yutao Zhu, Wei -Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：COORDINATION CHEMISTRY REVIEWS 2024
- 关键词：Dicyanomethylene-4H-pyran Near-infrared Fluorescent probe Photodynamic therapy Photothermal therapy
- Nickel-Catalyzed Carbonylative Negishi Cross-Coupling of Unactivated Secondary Alkyl Electrophiles with 1 atm CO Gas被引量：36收藏
- 作者：Zhang, Yetong Cao, Qihang Xi, Yang Wu, Xianqing Qu, Jingping Chen, Yifeng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2024
- 关键词：Carbonylation - Ketones - Nickel compounds - Organometallics - Sulfur compounds
- Dual- channel near- infrared fluorescent probe for real- time tracking of endogenous c- glutamyl transpeptidase activity被引量：36收藏
- 作者：Bai, Bing Yan, Chenxu Zhang, Yutao Guo, Zhiqian Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2018
- A "crossbreeding" dyad strategy for bright and small-molecular weight near-infrared fluorogens: From the structural design to boost aggregation-induced emission被引量：35收藏
- 作者：Li, Juan Zhao, Meiling Huang, Jialiang Liu, Pengqi Luo, Xinyu Zhang, Yutao Yan, Chenxu Zhu, Wei -Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol
- 来源：COORDINATION CHEMISTRY REVIEWS 2022
- 关键词：Crossbreeding Near-infrared Fluorescent probe Aggregation-induced emission Bioimaging
- "Crossbreeding" Small-Molecular Weight NIR-II Flavchromenes Endows Activatable Multiplexed In Vivo Imaging被引量：22收藏
- 作者：Zhang, Liao Zhang, Yutao Chi, Weijie Yan, Chenxu Zhao, Zijun Liu, Xiaogang Zhu, Wei-Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Singapore Univ Technol & Design
- 来源：ACS MATERIALS LETTERS 2022
- 关键词：Biocompatibility - Bioimaging - Chemical stability - Fluorophores - Infrared devices
- A Mitochondrial-targeted curcumin-based fluorescent probe for real-time tracking endogenous hydrogen peroxide in living cells被引量：20收藏
- 作者：Zhu, Mingming Wang, Ting Zhang, Yutao Nong, Jiahuan Guo, Zhiqian
- 机构：Shanghai Jiao Tong Univ;East China Univ Sci & Technol
- 来源：SENSORS AND ACTUATORS B-CHEMICAL 2023
- 关键词：Fluorescent probe Dual -channel Near -infrared Hydrogen peroxide Mitochondrialtargeting
- Activatable BODIPY-chromene NIR-II probes with small spectral crosstalk enable high-contrast in vivo bioimaging被引量：19收藏
- 作者：Zhang, Liao Yan, Chenxu Zhang, Yutao Ma, Dun Huang, Jialiang Zhao, Zijun Tao, Yining Liu, Caiqi Li, Juan Zhu, Wei-Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2023
- 关键词：Bioimaging - Chromophores - Crosstalk - Infrared devices
- A de novo zwitterionic strategy of ultra-stable chemiluminescent probes: highly selective sensing of singlet oxygen in FDA-approved phototherapy被引量：18收藏
- 作者：Lu, Yao Zhang, Yutao Wu, Xia Pu, Ruihua Yan, Chenxu Liu, Weimin Liu, Xiaogang Guo, Zhiqian Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;Singapore Univ Technol & Design;ShanghaiTech Univ
- 来源：CHEMICAL SCIENCE 2024
- 关键词：Chemiluminescence - Excited states - Infrared devices - Ketones - Mammals - Medical applications - Oxygen - Photodynamic therapy - Signal to noise ratio
- Ultra-high signal-to-noise ratio near-infrared chemiluminescent probe for in vivo sensing singlet oxygen被引量：10收藏
- 作者：Zhao, Meiling Lu, Yao Zhang, Yutao Xue, Haoyun Guo, Zhiqian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHINESE CHEMICAL LETTERS 2025
- 关键词：Fluorescent probe Near-infrared Chemiluminescent Singlet oxygen Bioimaging
- Palladium(ii)-catalyzed enantioselective intermolecular oxidative diarylation of internal enamides被引量：9收藏
- 作者：Xia, Tingting Xi, Yang Ding, Haojie Zhang, Yetong Fang, Ke Wu, Xianqing Qu, Jingping Chen, Yifeng
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：CHEMICAL COMMUNICATIONS 2022
- 关键词：Enantioselectivity - Palladium compounds
- Sequence-activated chemiluminescence probes: programmable illumination for high-contrast in vivo sensing and imaging被引量：8收藏
- 作者：Zhang, Yutao Li, Juan Zhu, Wei-Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：SCIENCE CHINA-CHEMISTRY 2025
- 关键词：chemiluminescnece sequence-activation in-vivo bioimaging cyclic peroxide
- A two-dimensional fluorescence and chemiluminescence orthogonal probe for discriminating and quantifying similar proteins被引量：7收藏
- 作者：Li, Juan Zhao, Xiuyan Zhang, Yutao Lu, Yao Xue, Haoyun Li, Dan Liu, Qiang Yan, Chenxu Chi, Weijie Xiao, Xingqing Zhu, Wei-Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol;Hainan Univ
- 来源：CHEMICAL SCIENCE 2025
- 关键词：Cycloaddition - Transient absorption spectroscopy
- Bidirectional Single-Molecule Photoconductors Based on ESIPT被引量：4收藏
- 作者：Qiu, Jin Jiang, Shuyu Zhang, Yutian Qiao, Mengyuan Wang, Rui Chen, Xuanying Zhang, Zhiyun Zou, Qi Tian, He
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2025
- 关键词：Excited states - Molecules - Orbital calculations - Photoconducting materials - Quantum theory - Scaffolds - Scaffolds (biology)
- Mechanisms and characteristics of subcapsular sinus macrophages in tumor immunity: a narrative review被引量：3收藏
- 作者：Su, Feng Zhang, Yutao Maimaiti, Subinuer Chen, Shanglin Shen, Yaxing Feng, Mingxiang Guo, Zhiqiang Tan, Lijie He, Jie
- 机构：Chinese Acad Med Sci & Peking Union Med Coll;Fudan Univ;East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ
- 来源：TRANSLATIONAL CANCER RESEARCH 2023
- 关键词：Macrophages subcapsular sinus tumor immunity
- Dual-Responsive Fluorescent Probes: advances in Biosensing, Diagnosis and Therapy被引量：2收藏
- 作者：Liu, Jihong Wu, Luling Zhu, Zhirong Yan, Chenxu Zhang, Yutao Yang, Ting Xu, Shiyun Yang, Haojian Liu, Shichang Tang, Wenjun Ma, Xiaoyu Lewis, Simon E. Wang, Qi James, Tony D. Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Bath;East China Univ Sci & Technol;Henan Normal Univ
- 来源：ADVANCED FUNCTIONAL MATERIALS 2026
- 关键词：biosensing diagnosis dual-responsive fluorescent probes therapy
- Nickel-catalyzed acylation of vinylpyridine with alkylzincs under 1 atm CO被引量：2收藏
- 作者：Huang, Wenyi Wang, Chenglong Zhang, Yetong Qu, Jingping Chen, Yifeng
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：ORGANIC & BIOMOLECULAR CHEMISTRY 2024
- 关键词：Atmospheric pressure - Catalysis - Nickel - Pyridine - Synthesis (chemical)
- Protein-Triggered Reassembly of Quinocyanine Nanosheets for Intraoperative NIR-II Cholangiography被引量：2收藏
- 作者：Zhang, Yutao Wu, Menglan Li, Wennan Liu, Zhiyong Liu, Caiqi Wu, Yue Yan, Chenxu Xu, Yisheng Zhu, Wei-Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ;East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2026
- 关键词：Activatable imaging Cholangiography Fluorescent probe NIR-II fluorescence Quinocyanine dye
- Oral ER-targeting near-infrared nanoprobes enable real-time intraoperative thoracic duct mapping in swine被引量：2收藏
- 作者：Zhang, Yutao Li, Wennan Yu, Qi Subinuer, Maimaiti Shen, Yaxing Feng, Mingxiang Guo, Zhiqian Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;Fudan Univ
- 来源：SCIENCE CHINA-CHEMISTRY 2026
- 关键词：near-infrared dye fluorescent probe oral administration cyanine surgical navigation thoracic duct formulation
- A sequence-activated near-infrared fluorescence probe for precisely tracking in vivo senescence被引量：1收藏
- 作者：Nong, Jiahuan Li, Pengcheng Zhu, Mingming Li, Yifeng Wang, Changsheng Zhang, Yutao Yan, Chenxu Guo, Zhiqian
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;East China Normal Univ;Shanghai Jiao Tong Univ;East China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2025
- 关键词：Cells - Cytology
- Controllable Structure and Fluorescence Enhancement of ACQ Dye Nanoparticles Based on the FNP Process被引量：1收藏
- 作者：Wu, Yue Zhang, Yutao Guo, Zhiqian Xu, Yisheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Tec hnol
- 来源：POLYMERS 2025
- 关键词：fluorescence nanoparticles ACQ effect flash nanoprecipitation fluorescence enhancement
- Fluorescence lifetime clocks quantify senescence and aging被引量：1收藏
- 作者：Yan, Chenxu Liu, Caiqi Liu, Bofang Zheng, Qiaoqiao Zhao, Xingyuan Lu, Sirui Fu, Xiaoqing Li, Wennan Li, Juan Li, Dan Yao, Yongkang Zhang, Yutao Zhu, Huanhu Shi, Ping Zhu, Wei-Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;ShanghaiTech Univ;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：NATURE AGING 2025
- Sequential H2S-Triggered Redox Relay Nanoprobes for Self-Sustained Chem-Illuminating Cascade Photodynamic Therapy被引量：0收藏
- 作者：Yang, Jing Lu, Yao Zhang, Yutao Zhao, Xiuyan Li, Xie Yan, Chenxu Zhao, Yuzheng Zhu, Wei-Hong Guo, Zhiqian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2026
- 关键词：activatable chemiluminescent probe hydrogen sulfide nanophotosensitizer photodynamic therapy
- Oxygen-Driven [2+2] Photocycloaddition for In Vivo Chemiluminescence被引量：0收藏
- 作者：Zhang, Yutao Li, Juan Pu, Ruihua Chi, Weijie Pan, Yufei Dong, Liwei Lu, Yao Zhao, Xiuyan Yang, Jing Yan, Chenxu Liu, Weimin Guo, Zhiqian Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;ShanghaiTech Univ;Hainan Univ;Naval Med Univ
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2026
